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PDB: 333 results

6ZXU
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BU of 6zxu by Molmil
Catabolic reductive dehalogenase NpRdhA, N-terminally tagged.
Descriptor: CHLORIDE ION, COBALAMIN, IRON/SULFUR CLUSTER, ...
Authors:Leys, D, Halliwell, T.
Deposit date:2020-07-30
Release date:2020-09-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Catabolic Reductive Dehalogenase Substrate Complex Structures Underpin Rational Repurposing of Substrate Scope.
Microorganisms, 8, 2020
6TIH
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BU of 6tih by Molmil
Structure of A. niger Fdc WT in complex with benzothiophene 2 carboxylic acid
Descriptor: Ferulic acid decarboxylase 1, MANGANESE (II) ION, POTASSIUM ION, ...
Authors:Leys, D.
Deposit date:2019-11-22
Release date:2020-06-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.021 Å)
Cite:Enzymatic C-H activation of aromatic compounds through CO 2 fixation.
Nat.Chem.Biol., 16, 2020
6TIE
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BU of 6tie by Molmil
Structure of A. niger Fdc I327S variant in complex with indol-2-carboxylic acid
Descriptor: 1H-indole-2-carboxylic acid, Ferulic acid decarboxylase 1, MANGANESE (II) ION, ...
Authors:Leys, D.
Deposit date:2019-11-22
Release date:2020-06-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.06 Å)
Cite:Enzymatic C-H activation of aromatic compounds through CO 2 fixation.
Nat.Chem.Biol., 16, 2020
6TIB
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BU of 6tib by Molmil
Structure of A. niger Fdc I327S variant in complex with 2 naphthoic acid
Descriptor: DI(HYDROXYETHYL)ETHER, Ferulic acid decarboxylase 1, MANGANESE (II) ION, ...
Authors:Leys, D.
Deposit date:2019-11-22
Release date:2020-06-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Enzymatic C-H activation of aromatic compounds through CO 2 fixation.
Nat.Chem.Biol., 16, 2020
6TIJ
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BU of 6tij by Molmil
Structure of A. niger Fdc WT in complex with indol-2-carboxylic acid
Descriptor: 1H-indole-2-carboxylic acid, Ferulic acid decarboxylase 1, MANGANESE (II) ION, ...
Authors:Leys, D.
Deposit date:2019-11-22
Release date:2020-06-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Enzymatic C-H activation of aromatic compounds through CO 2 fixation.
Nat.Chem.Biol., 16, 2020
3CXV
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BU of 3cxv by Molmil
Crystal structure of the Cytochrome P450 CYP121 A233G mutant from Mycobacterium tuberculosis
Descriptor: Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Leys, D.
Deposit date:2008-04-25
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv.
J.Biol.Chem., 283, 2008
3CXX
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BU of 3cxx by Molmil
Crystal structure of cytochrome P450 CYP121 F338H from M. tuberculosis
Descriptor: Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Leys, D.
Deposit date:2008-04-25
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterization of the active site structure of CY121
TO BE PUBLISHED
3CY0
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BU of 3cy0 by Molmil
Crystal structure of cytochrome P450 CYP121 S237A mutant from Mycobacterium tuberculosis
Descriptor: Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Leys, D.
Deposit date:2008-04-25
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterisation of active site structure of cytochrome CYP121
TO BE PUBLISHED
3CY1
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BU of 3cy1 by Molmil
Crystal structure of the cytochrome P450 CYP121 S279A mutant from M. tuberculosis
Descriptor: Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Leys, D.
Deposit date:2008-04-25
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Characterisation of active site of cytochrome P450 CYP121
TO BE PUBLISHED
5LW6
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BU of 5lw6 by Molmil
Crystal structure of a Se-Met substituted Dictyostelium discoideum ADP-ribose binding macrodomain (residues 342-563) of DDB_G0293866
Descriptor: DDB_G0293866
Authors:Leys, D, Barkauskaite, E, Pinero, B.B, Ahel, I.
Deposit date:2016-09-15
Release date:2016-09-28
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The role of ADP-ribosylation in regulating DNA interstrand crosslink repair.
J.Cell.Sci., 129, 2016
7ABO
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BU of 7abo by Molmil
Structure of the N318H variant of the reversible pyrrole-2-carboxylic acid decarboxylase PA0254/HudA in complex with FMN
Descriptor: FLAVIN MONONUCLEOTIDE, MANGANESE (II) ION, SODIUM ION, ...
Authors:Leys, D, Marshall, S.A.
Deposit date:2020-09-08
Release date:2021-04-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure and Mechanism of Pseudomonas aeruginosa PA0254/HudA, a prFMN-Dependent Pyrrole-2-carboxylic Acid Decarboxylase Linked to Virulence.
Acs Catalysis, 11, 2021
7ABN
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BU of 7abn by Molmil
Structure of the reversible pyrrole-2-carboxylic acid decarboxylase PA0254/HudA
Descriptor: 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, IMIDAZOLE, MANGANESE (II) ION, ...
Authors:Leys, D.
Deposit date:2020-09-08
Release date:2021-04-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and Mechanism of Pseudomonas aeruginosa PA0254/HudA, a prFMN-Dependent Pyrrole-2-carboxylic Acid Decarboxylase Linked to Virulence.
Acs Catalysis, 11, 2021
3CXZ
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BU of 3cxz by Molmil
Crystal structure of cytochrome P450 CYP121 R386L mutant from M. tuberculosis
Descriptor: Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Leys, D.
Deposit date:2008-04-25
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Characterization of active site structure of cytochrome P450 CYP121
TO BE PUBLISHED
3CXY
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BU of 3cxy by Molmil
Crystal structure of the cytochrome P450 CYP121 P346L mutant from M. tuberculosis
Descriptor: Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Leys, D.
Deposit date:2008-04-25
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Characterization of active site structure in CYP121
TO BE PUBLISHED
6ZY0
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BU of 6zy0 by Molmil
Catabolic reductive dehalogenase NpRdhA, N-terminally tagged, K488Q variant
Descriptor: CHLORIDE ION, COBALAMIN, IRON/SULFUR CLUSTER, ...
Authors:Leys, D, Halliwell, T.
Deposit date:2020-07-30
Release date:2020-09-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Catabolic Reductive Dehalogenase Substrate Complex Structures Underpin Rational Repurposing of Substrate Scope.
Microorganisms, 8, 2020
6ZXX
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BU of 6zxx by Molmil
Catabolic reductive dehalogenase NpRdhA, N-terminally tagged.
Descriptor: 3 bromo 4 hydroxybenzoic acid, 3,5-bis(bromanyl)-4-oxidanyl-benzoic acid, BROMIDE ION, ...
Authors:Leys, D, Halliwell, T.
Deposit date:2020-07-30
Release date:2020-09-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Catabolic Reductive Dehalogenase Substrate Complex Structures Underpin Rational Repurposing of Substrate Scope.
Microorganisms, 8, 2020
6ZY1
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BU of 6zy1 by Molmil
Catabolic reductive dehalogenase NpRdhA, N-terminally tagged in complex with 3-bromo-4-hydroxybenzoic acid
Descriptor: 3 bromo 4 hydroxybenzoic acid, COBALAMIN, IRON/SULFUR CLUSTER, ...
Authors:Leys, D, Halliwell, T.
Deposit date:2020-07-30
Release date:2020-09-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Catabolic Reductive Dehalogenase Substrate Complex Structures Underpin Rational Repurposing of Substrate Scope.
Microorganisms, 8, 2020
1D4C
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BU of 1d4c by Molmil
CRYSTAL STRUCTURE OF THE UNCOMPLEXED FORM OF THE FLAVOCYTOCHROME C FUMARATE REDUCTASE OF SHEWANELLA PUTREFACIENS STRAIN MR-1
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C FUMARATE REDUCTASE, HEME C, ...
Authors:Leys, D, Tsapin, A.S, Meyer, T.E, Cusanovich, M.A, Van Beeumen, J.J.
Deposit date:1999-10-03
Release date:1999-12-01
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and mechanism of the flavocytochrome c fumarate reductase of Shewanella putrefaciens MR-1.
Nat.Struct.Biol., 6, 1999
4L40
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BU of 4l40 by Molmil
Structure of the P450 OleT with a C20 fatty acid substrate bound
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, Terminal olefin-forming fatty acid decarboxylase, icosanoic acid
Authors:Leys, D.
Deposit date:2013-06-07
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and Biochemical Properties of the Alkene Producing Cytochrome P450 OleTJE (CYP152L1) from the Jeotgalicoccus sp. 8456 Bacterium.
J.Biol.Chem., 289, 2014
1D4D
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BU of 1d4d by Molmil
CRYSTAL STRUCTURE OF THE SUCCINATE COMPLEXED FORM OF THE FLAVOCYTOCHROME C FUMARATE REDUCTASE OF SHEWANELLA PUTREFACIENS STRAIN MR-1
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C FUMARATE REDUCTASE, HEME C, ...
Authors:Leys, D, Tsapin, A.S, Meyer, T.E, Cusanovich, M.A, Van Beeumen, J.J.
Deposit date:1999-10-03
Release date:1999-12-01
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and mechanism of the flavocytochrome c fumarate reductase of Shewanella putrefaciens MR-1.
Nat.Struct.Biol., 6, 1999
1D4E
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BU of 1d4e by Molmil
CRYSTAL STRUCTURE OF THE FLAVOCYTOCHROME C FUMARATE REDUCTASE OF SHEWANELLA PUTREFACIENS STRAIN MR-1 COMPLEXED WITH FUMARATE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C FUMARATE REDUCTASE, FUMARIC ACID, ...
Authors:Leys, D, Tsapin, A.S, Meyer, T.E, Cusanovich, M.A, Van Beeumen, J.J.
Deposit date:1999-10-03
Release date:1999-12-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and mechanism of the flavocytochrome c fumarate reductase of Shewanella putrefaciens MR-1.
Nat.Struct.Biol., 6, 1999
3SIG
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BU of 3sig by Molmil
The X-ray crystal structure of poly(ADP-ribose) glycohydrolase (PARG) bound to ADP-ribose from Thermomonospora curvata
Descriptor: [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, poly(ADP-ribose) glycohydrolase
Authors:Leys, D, Dunstan, M.S.
Deposit date:2011-06-18
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.
Nature, 477, 2011
1DW1
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BU of 1dw1 by Molmil
STRUCTURE OF THE CYANIDE COMPLEX OF SHP, AN OXYGEN BINDING CYTOCHROME C
Descriptor: CYANIDE ION, CYTOCHROME C, HEME C
Authors:Leys, D, Backers, K, Meyer, T.E, Hagen, W.R, Cusanovich, M.A, Van Beeumen, J.J.
Deposit date:2000-01-24
Release date:2000-06-28
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of an oxygen-binding cytochrome c from Rhodobacter sphaeroides.
J.Biol.Chem., 275, 2000
1DW3
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BU of 1dw3 by Molmil
STRUCTURE OF A REDUCED OXYGEN BINDING CYTOCHROME C
Descriptor: CYTOCHROME C, HEME C
Authors:Leys, D, Backers, K, Meyer, T.E, Hagen, W.R, Cusanovich, M.A, Van Beeumen, J.J.
Deposit date:2000-01-24
Release date:2000-06-28
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of an oxygen-binding cytochrome c from Rhodobacter sphaeroides.
J.Biol.Chem., 275, 2000
1DW2
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BU of 1dw2 by Molmil
STRUCTURE OF THE NITRIC OXIDE COMPLEX OF REDUCED SHP, AN OXYGEN BINDING CYTOCHROME C
Descriptor: CYTOCHROME C, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Leys, D, Backers, K, Meyer, T.E, Hagen, W.R, Cusanovich, M.A, Van Beeumen, J.J.
Deposit date:2000-01-24
Release date:2000-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of an oxygen-binding cytochrome c from Rhodobacter sphaeroides.
J.Biol.Chem., 275, 2000

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