3CXV

Crystal structure of the Cytochrome P450 CYP121 A233G mutant from Mycobacterium tuberculosis

Summary for 3CXV

Entry DOI	10.2210/pdb3cxv/pdb
Related	1N40 2IJ7 3CXX 3CXY 3CXZ 3CY0 3CY1
Descriptor	Cytochrome P450 121, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total)
Functional Keywords	cytochrome p450, cyp121, mycobacterium tuberculosis, cytoplasm, heme, iron, metal-binding, monooxygenase, oxidoreductase
Biological source	Mycobacterium tuberculosis
Cellular location	Cytoplasm (By similarity): P0A514
Total number of polymer chains	1
Total formula weight	44196.51
Authors	Leys, D. (deposition date: 2008-04-25, release date: 2008-09-23, Last modification date: 2023-08-30)
Primary citation	McLean, K.J.,Carroll, P.,Lewis, D.G.,Dunford, A.J.,Seward, H.E.,Neeli, R.,Cheesman, M.R.,Marsollier, L.,Douglas, P.,Smith, W.E.,Rosenkrands, I.,Cole, S.T.,Leys, D.,Parish, T.,Munro, A.W. Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv. J.Biol.Chem., 283:33406-33416, 2008 Cited by PubMed: 18818197 DOI: 10.1074/jbc.M802115200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation