3CXV
Crystal structure of the Cytochrome P450 CYP121 A233G mutant from Mycobacterium tuberculosis
Summary for 3CXV
Entry DOI | 10.2210/pdb3cxv/pdb |
Related | 1N40 2IJ7 3CXX 3CXY 3CXZ 3CY0 3CY1 |
Descriptor | Cytochrome P450 121, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total) |
Functional Keywords | cytochrome p450, cyp121, mycobacterium tuberculosis, cytoplasm, heme, iron, metal-binding, monooxygenase, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Cellular location | Cytoplasm (By similarity): P0A514 |
Total number of polymer chains | 1 |
Total formula weight | 44196.51 |
Authors | Leys, D. (deposition date: 2008-04-25, release date: 2008-09-23, Last modification date: 2023-08-30) |
Primary citation | McLean, K.J.,Carroll, P.,Lewis, D.G.,Dunford, A.J.,Seward, H.E.,Neeli, R.,Cheesman, M.R.,Marsollier, L.,Douglas, P.,Smith, W.E.,Rosenkrands, I.,Cole, S.T.,Leys, D.,Parish, T.,Munro, A.W. Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv. J.Biol.Chem., 283:33406-33416, 2008 Cited by PubMed: 18818197DOI: 10.1074/jbc.M802115200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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