Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 11 件
2G2H
DownloadVisualize
BU of 2g2h by Molmil
A Src-like Inactive Conformation in the Abl Tyrosine Kinase Domain
分子名称: 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, Abl Tyrosine
著者Levinson, N.M, Kuchment, O.
登録日2006-02-16
公開日2006-05-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A SRC-like inactive conformation in the abl tyrosine kinase domain.
Plos Biol., 4, 2006
2G2F
DownloadVisualize
BU of 2g2f by Molmil
A Src-like Inactive Conformation in the Abl Tyrosine Kinase Domain
分子名称: ATP-Peptide Conjugate, Abl Kinase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Levinson, N.M, Kuchment, O.
登録日2006-02-15
公開日2006-05-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A SRC-like inactive conformation in the abl tyrosine kinase domain.
Plos Biol., 4, 2006
2G1T
DownloadVisualize
BU of 2g1t by Molmil
A Src-like Inactive Conformation in the Abl Tyrosine Kinase Domain
分子名称: ATP-Peptide Conjugate, MAGNESIUM ION, Proto-oncogene tyrosine-protein kinase ABL1, ...
著者Levinson, N.M, Kuchment, O.
登録日2006-02-14
公開日2006-05-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A SRC-like inactive conformation in the abl tyrosine kinase domain.
Plos Biol., 4, 2006
2G2I
DownloadVisualize
BU of 2g2i by Molmil
A Src-like Inactive Conformation in the Abl Tyrosine Kinase Domain
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-Peptide Conjugate, Abl Tyrosine Kinase
著者Levinson, N.M, Kuchment, O.
登録日2006-02-16
公開日2006-05-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献A SRC-like inactive conformation in the abl tyrosine kinase domain.
Plos Biol., 4, 2006
3D7U
DownloadVisualize
BU of 3d7u by Molmil
Structural basis for the recognition of c-Src by its inactivator Csk
分子名称: Proto-oncogene tyrosine-protein kinase Src, Tyrosine-protein kinase CSK
著者Levinson, N.M, Seeliger, M.A, Cole, P.A, Kuriyan, J.
登録日2008-05-21
公開日2008-08-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (4.111 Å)
主引用文献Structural basis for the recognition of c-Src by its inactivator Csk.
Cell(Cambridge,Mass.), 134, 2008
3D7T
DownloadVisualize
BU of 3d7t by Molmil
Structural basis for the recognition of c-Src by its inactivator Csk
分子名称: Proto-oncogene tyrosine-protein kinase Src, STAUROSPORINE, Tyrosine-protein kinase CSK
著者Levinson, N.M, Seeliger, M.A, Cole, P.A, Kuriyan, J.
登録日2008-05-21
公開日2008-08-05
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.899 Å)
主引用文献Structural basis for the recognition of c-Src by its inactivator Csk.
Cell(Cambridge,Mass.), 134, 2008
4MXO
DownloadVisualize
BU of 4mxo by Molmil
human Src kinase bound to kinase inhibitor bosutinib
分子名称: 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile, Proto-oncogene tyrosine-protein kinase Src
著者Levinson, N.M, Boxer, S.G.
登録日2013-09-26
公開日2013-12-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.105 Å)
主引用文献A conserved water-mediated hydrogen bond network defines bosutinib's kinase selectivity.
Nat.Chem.Biol., 10, 2014
4MXY
DownloadVisualize
BU of 4mxy by Molmil
Src M314L T338M double mutant bound to kinase inhibitor bosutinib
分子名称: 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile, Proto-oncogene tyrosine-protein kinase Src
著者Levinson, N.M, Boxer, S.G.
登録日2013-09-26
公開日2013-12-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.582 Å)
主引用文献A conserved water-mediated hydrogen bond network defines bosutinib's kinase selectivity.
Nat.Chem.Biol., 10, 2014
4MXX
DownloadVisualize
BU of 4mxx by Molmil
Human Src A403T mutant bound to kinase inhibitor bosutinib
分子名称: 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile, Proto-oncogene tyrosine-protein kinase Src
著者Levinson, N.M, Boxer, S.G.
登録日2013-09-26
公開日2013-12-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A conserved water-mediated hydrogen bond network defines bosutinib's kinase selectivity.
Nat.Chem.Biol., 10, 2014
4MXZ
DownloadVisualize
BU of 4mxz by Molmil
Src M314L T338M double mutant bound to kinase inhibitor bosutinib
分子名称: 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile, Proto-oncogene tyrosine-protein kinase Src
著者Levinson, N.M, Boxer, S.G.
登録日2013-09-26
公開日2013-12-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.582 Å)
主引用文献A conserved water-mediated hydrogen bond network defines bosutinib's kinase selectivity.
Nat.Chem.Biol., 10, 2014
3UE4
DownloadVisualize
BU of 3ue4 by Molmil
Structural and spectroscopic analysis of the kinase inhibitor bosutinib binding to the Abl tyrosine kinase domain
分子名称: 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile, Tyrosine-protein kinase ABL1
著者Boxer, S.G, Levinson, N.M.
登録日2011-10-28
公開日2012-04-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.424 Å)
主引用文献Structural and spectroscopic analysis of the kinase inhibitor bosutinib and an isomer of bosutinib binding to the abl tyrosine kinase domain.
Plos One, 7, 2012

222624

件を2024-07-17に公開中

PDB statisticsPDBj update infoContact PDBjnumon