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PDB: 80 results

1CIA
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BU of 1cia by Molmil
REPLACEMENT OF CATALYTIC HISTIDINE-195 OF CHLORAMPHENICOL ACETYLTRANSFERASE: EVIDENCE FOR A GENERAL BASE ROLE FOR GLUTAMATE
Descriptor: BETA-MERCAPTOETHANOL, CHLORAMPHENICOL ACETYLTRANSFERASE, COBALT (II) ION
Authors:Leslie, A.G.W, Gibbs, M.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Replacement of catalytic histidine-195 of chloramphenicol acetyltransferase: evidence for a general base role for glutamate.
Biochemistry, 33, 1994
5F8U
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BU of 5f8u by Molmil
Ligand occupancy in crystal structure of beta1-adrenergic receptor previously submitted by Huang et al
Descriptor: 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, Beta-1 adrenergic receptor
Authors:Leslie, A.G.W, Warne, A, Tate, C.G.
Deposit date:2015-12-09
Release date:2015-12-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Ligand occupancy in crystal structure of Beta1 adrenergic G protein coupled receptor
Nat.Struct.Mol.Biol., 22, 2015
1QCA
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BU of 1qca by Molmil
QUADRUPLE MUTANT Q92C, N146F, Y168F, I172V TYPE III CAT COMPLEXED WITH FUSIDIC ACID. CRYSTALS GROWN AT PH 6.3. X-RAY DATA COLLECTED AT ROOM TEMPERATURE
Descriptor: COBALT (II) ION, FUSIDIC ACID, TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE
Authors:Leslie, A.G.W.
Deposit date:1995-08-03
Release date:1995-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Steroid recognition by chloramphenicol acetyltransferase: engineering and structural analysis of a high affinity fusidic acid binding site.
J.Mol.Biol., 254, 1995
3CLA
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BU of 3cla by Molmil
REFINED CRYSTAL STRUCTURE OF TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE AT 1.75 ANGSTROMS RESOLUTION
Descriptor: CHLORAMPHENICOL, COBALT (II) ION, TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE
Authors:Leslie, A.G.W.
Deposit date:1990-07-09
Release date:1990-10-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Refined crystal structure of type III chloramphenicol acetyltransferase at 1.75 A resolution.
J.Mol.Biol., 213, 1990
4CLA
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BU of 4cla by Molmil
ALTERNATIVE BINDING MODES FOR CHLORAMPHENICOL AND 1-SUBSTITUTED CHLORAMPHENICOL ANALOGUES REVEALED BY SITE-DIRECTED MUTAGENESIS AND X-RAY CRYSTALLOGRAPHY OF CHLORAMPHENICOL ACETYLTRANSFERASE
Descriptor: CHLORAMPHENICOL, COBALT (II) ION, TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE
Authors:Leslie, A.G.W.
Deposit date:1990-10-23
Release date:1992-01-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Alternative binding modes for chloramphenicol and 1-substituted chloramphenicol analogues revealed by site-directed mutagenesis and X-ray crystallography of chloramphenicol acetyltransferase.
Biochemistry, 30, 1991
1QGT
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BU of 1qgt by Molmil
HUMAN HEPATITIS B VIRAL CAPSID (HBCAG)
Descriptor: PROTEIN (HBV CAPSID PROTEIN)
Authors:Leslie, A.G.W, Wynne, S.A, Crowther, R.A.
Deposit date:1999-05-05
Release date:1999-06-25
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The crystal structure of the human hepatitis B virus capsid.
Mol.Cell, 3, 1999
1EFR
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BU of 1efr by Molmil
BOVINE MITOCHONDRIAL F1-ATPASE COMPLEXED WITH THE PEPTIDE ANTIBIOTIC EFRAPEPTIN
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BOVINE MITOCHONDRIAL F1-ATPASE SUBUNIT ALPHA, BOVINE MITOCHONDRIAL F1-ATPASE SUBUNIT BETA, ...
Authors:Abrahams, J.P, Buchanan, S.K, Van Raaij, M.J, Fearnley, I.M, Leslie, A.G.W, Walker, J.E.
Deposit date:1996-05-24
Release date:1997-02-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Structure of Bovine F1-ATPase Complexed with the Peptide Antibiotic Efrapeptin.
Proc.Natl.Acad.Sci.USA, 93, 1996
1W0K
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BU of 1w0k by Molmil
ADP inhibited bovine F1-ATPase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP SYNTHASE ALPHA CHAIN HEART ISOFORM, MITOCHONDRIAL PRECURSOR, ...
Authors:Kagawa, R, Montgomery, M.G, Braig, K, Walker, J.E, Leslie, A.G.W.
Deposit date:2004-06-08
Release date:2004-07-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The Structure of Bovine F1-ATPase Inhibited by Adp and Beryllium Fluoride
Embo J., 23, 2004
1W0J
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BU of 1w0j by Molmil
Beryllium fluoride inhibited bovine F1-ATPase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP SYNTHASE ALPHA CHAIN HEART ISOFORM, MITOCHONDRIAL PRECURSOR, ...
Authors:Kagawa, R, Montgomery, M.G, Braig, K, Walker, J.E, Leslie, A.G.W.
Deposit date:2004-06-08
Release date:2004-07-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Structure of Bovine F1-ATPase Inhibited by Adp and Beryllium Fluoride
Embo J., 23, 2004
5IK2
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BU of 5ik2 by Molmil
Caldalaklibacillus thermarum F1-ATPase (epsilon mutant)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP synthase epsilon chain, ATP synthase gamma chain, ...
Authors:Ferguson, S.A, Cook, G.M, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
Deposit date:2016-03-03
Release date:2016-09-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Regulation of the thermoalkaliphilic F1-ATPase from Caldalkalibacillus thermarum.
Proc.Natl.Acad.Sci.USA, 113, 2016
2CK3
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BU of 2ck3 by Molmil
Azide inhibited bovine F1-ATPase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL, ...
Authors:Bowler, M.W, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
Deposit date:2006-04-10
Release date:2006-05-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:How Azide Inhibits ATP Hydrolysis by the F-Atpases.
Proc.Natl.Acad.Sci.USA, 103, 2006
5A8E
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BU of 5a8e by Molmil
thermostabilised beta1-adrenoceptor with rationally designed inverse agonist 7-methylcyanopindolol bound
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 4-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-7-methyl-1H-indole-2-carbonitrile, ...
Authors:Sato, T, Baker, J.G, Warne, T, Brown, G.A, Congreve, M, Leslie, A.G.W, Tate, C.G.
Deposit date:2015-07-15
Release date:2015-09-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Pharmacological Analysis and Structure Determination of 7-Methylcyanopindolol-Bound Beta1-Adrenergic Receptor.
Mol.Pharmacol., 88, 2015
1SKY
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BU of 1sky by Molmil
CRYSTAL STRUCTURE OF THE NUCLEOTIDE FREE ALPHA3BETA3 SUB-COMPLEX OF F1-ATPASE FROM THE THERMOPHILIC BACILLUS PS3
Descriptor: F1-ATPASE, SULFATE ION
Authors:Shirakihara, Y, Leslie, A.G.W, Abrahams, J.P, Walker, J.E, Ueda, T, Sekimoto, Y, Kambara, M, Saika, K, Kagawa, Y, Yoshida, M.
Deposit date:1997-02-26
Release date:1998-03-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The crystal structure of the nucleotide-free alpha 3 beta 3 subcomplex of F1-ATPase from the thermophilic Bacillus PS3 is a symmetric trimer.
Structure, 5, 1997
2CLA
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BU of 2cla by Molmil
CRYSTAL STRUCTURE OF THE ASP-199-ASN MUTANT OF CHLORAMPHENICOL ACETYLTRANSFERASE TO 2.35 ANGSTROMS RESOLUTION. STRUCTURAL CONSEQUENCES OF DISRUPTION OF A BURIED SALT-BRIDGE
Descriptor: CHLORAMPHENICOL ACETYLTRANSFERASE, COBALT (II) ION
Authors:Gibbs, M.R, Moody, P.C.E, Leslie, A.G.W.
Deposit date:1990-04-05
Release date:1990-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of the aspartic acid-199----asparagine mutant of chloramphenicol acetyltransferase to 2.35-A resolution: structural consequences of disruption of a buried salt bridge.
Biochemistry, 29, 1990
4YXW
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BU of 4yxw by Molmil
Bovine heart mitochondrial F1-ATPase inhibited by AMP-PNP and ADP in the presence of thiophosphate.
Descriptor: ATP synthase subunit alpha, mitochondrial, ATP synthase subunit beta, ...
Authors:Bason, J.V, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
Deposit date:2015-03-23
Release date:2015-05-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How release of phosphate from mammalian F1-ATPase generates a rotary substep.
Proc.Natl.Acad.Sci.USA, 112, 2015
4Z1M
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BU of 4z1m by Molmil
Bovine F1-ATPase inhibited by three copies of the inhibitor protein IF1 crystallised in the presence of thiophosphate.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ...
Authors:Bason, J.V, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
Deposit date:2015-03-27
Release date:2015-05-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:How release of phosphate from mammalian F1-ATPase generates a rotary substep.
Proc.Natl.Acad.Sci.USA, 112, 2015
4UHR
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BU of 4uhr by Molmil
Thermostabilised HUMAN A2a Receptor with CGS21680 bound
Descriptor: 2-[P-(2-CARBOXYETHYL)PHENYLETHYL-AMINO]-5'-N-ETHYLCARBOXAMIDO ADENOSINE, THERMOSTABILISED HUMAN A2A RECEPTOR
Authors:Lebon, G, Edwards, P.C, Leslie, A.G.W, Tate, C.G.
Deposit date:2015-03-25
Release date:2015-04-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Determinants of Cgs21680 Binding to the Human Adenosine A2A Receptor.
Mol.Pharmacol., 87, 2015
4UG2
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BU of 4ug2 by Molmil
Thermostabilised HUMAN A2a Receptor with CGS21680 bound
Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-[P-(2-CARBOXYETHYL)PHENYLETHYL-AMINO]-5'-N-ETHYLCARBOXAMIDO ADENOSINE, THERMOSTABILISED HUMAN A2A RECEPTOR
Authors:Lebon, G, Edwards, P.C, Leslie, A.G.W, Tate, C.G.
Deposit date:2015-03-21
Release date:2015-04-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Determinants of Cgs21680 Binding to the Human Adenosine A2A Receptor.
Mol.Pharmacol., 87, 2015
5A3E
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BU of 5a3e by Molmil
2.5A structure of lysozyme determined by MicroED with data from a single crystal
Descriptor: LYSOZYME C
Authors:Nannenga, B.L, Shi, D, Leslie, A.G.W, Gonen, T.
Deposit date:2015-05-28
Release date:2015-06-17
Last modified:2024-01-10
Method:ELECTRON CRYSTALLOGRAPHY (2.501 Å)
Cite:High-Resolution Structure Determination by Continuous-Rotation Data Collection in Microed.
Nat.Methods, 11, 2014
1H8E
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BU of 1h8e by Molmil
(ADP.AlF4)2(ADP.SO4) bovine F1-ATPase (all three catalytic sites occupied)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BOVINE MITOCHONDRIAL F1-ATPASE, GLYCEROL, ...
Authors:Menz, R.I, Walker, J.E, Leslie, A.G.W.
Deposit date:2001-02-02
Release date:2001-08-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Bovine Mitochondrial F1-ATPase with Nucleotide Bound to All Three Catalytic Sites: Implications for the Mechanism of Rotary Catalysis
Cell(Cambridge,Mass.), 106, 2001
5CDF
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BU of 5cdf by Molmil
Structure at 2.3 A of the alpha/beta monomer of the F-ATPase from Paracoccus denitrificans
Descriptor: ATP synthase subunit alpha, ATP synthase subunit beta, GLYCEROL, ...
Authors:Morales-Rios, E, Montgomery, M.G, Leslie, A.G.W, Garcia-Trejo, J.J, Walker, J.E.
Deposit date:2015-07-03
Release date:2015-10-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a catalytic dimer of the alpha- and beta-subunits of the F-ATPase from Paracoccus denitrificans at 2.3 angstrom resolution.
Acta Crystallogr.,Sect.F, 71, 2015
5COD
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BU of 5cod by Molmil
Bovine heart complex I membrane domain
Descriptor: NADH-ubiquinone oxidoreductase chain 4, NADH-ubiquinone oxidoreductase chain 5, SDAP, ...
Authors:Zhu, J, Hirst, J, King, M.S, Yu, M, Leslie, A.G.W, Klipcan, L.
Deposit date:2015-07-20
Release date:2015-09-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (6.74 Å)
Cite:Structure of subcomplex I beta of mammalian respiratory complex I leads to new supernumerary subunit assignments.
Proc.Natl.Acad.Sci.USA, 112, 2015
5DN6
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BU of 5dn6 by Molmil
ATP synthase from Paracoccus denitrificans
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F0 subcomplex C subunit, ...
Authors:Morales-Rios, E, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
Deposit date:2015-09-09
Release date:2015-10-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.98 Å)
Cite:Structure of ATP synthase from Paracoccus denitrificans determined by X-ray crystallography at 4.0 angstrom resolution.
Proc.Natl.Acad.Sci.USA, 112, 2015
1E79
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BU of 1e79 by Molmil
Bovine F1-ATPase inhibited by DCCD (dicyclohexylcarbodiimide)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP SYNTHASE ALPHA CHAIN HEART ISOFORM, ...
Authors:Gibbons, C, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
Deposit date:2000-08-25
Release date:2000-11-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of the Central Stalk in Bovine F(1)-ATPase at 2.4 A Resolution.
Nat.Struct.Biol., 7, 2000
1H8H
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BU of 1h8h by Molmil
Bovine mitochondrial F1-ATPase crystallised in the presence of 5mm AMPPNP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, BOVINE MITOCHONDRIAL F1-ATPASE, ...
Authors:Braig, K, Menz, R.I, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
Deposit date:2001-02-06
Release date:2001-04-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Structure and Nucleotide Occupancy of Bovine Mitochondrial F(1)-ATPase are not Influenced by Crystallisation at High Concentrations of Nucleotide
FEBS Lett., 494, 2001

 

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