1QCA

QUADRUPLE MUTANT Q92C, N146F, Y168F, I172V TYPE III CAT COMPLEXED WITH FUSIDIC ACID. CRYSTALS GROWN AT PH 6.3. X-RAY DATA COLLECTED AT ROOM TEMPERATURE

Summary for 1QCA

• Entry DOI: 10.2210/pdb1qca/pdb
• Descriptor: TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE, COBALT (II) ION, FUSIDIC ACID, ... (4 entities in total)
• Functional Keywords: chloramphenicol, fusidate, steroid, transferase (acyltransferase)
• Biological source: Shigella flexneri
• Total number of polymer chains: 1
• Total formula weight: 25634.13

Authors

Leslie, A.G.W. (deposition date: 1995-08-03, release date: 1995-10-15, Last modification date: 2024-02-14)

• Primary citation: Murray, I.A.,Cann, P.A.,Day, P.J.,Derrick, J.P.,Sutcliffe, M.J.,Shaw, W.V.,Leslie, A.G.; Steroid recognition by chloramphenicol acetyltransferase: engineering and structural analysis of a high affinity fusidic acid binding site.; J.Mol.Biol., 254:993-1005, 1995; PubMed: 7500366; DOI: 10.1006/jmbi.1995.0671

Experimental method

X-RAY DIFFRACTION (2.2 Å)