5CNH
 
 | | X-ray structure of perdeuterated wild-type TTR at 1.42A resolution | | 分子名称: | Transthyretin | | 著者 | Yee, A.W, Moulin, M, Mossou, E, Haertlein, M, Mitchell, E.P, Cooper, J.B, Forsyth, V.T. | | 登録日 | 2015-07-17 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Impact of Deuteration on the Assembly Kinetics of Transthyretin Monitored by Native Mass Spectrometry and Implications for Amyloidoses.
Angew.Chem.Int.Ed.Engl., 55, 2016
|
|
5DPZ
 | | Endothiapepsin in complex with fragment 31 | | 分子名称: | 2-methylaniline, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Radeva, N, Uehlein, M, Weiss, M, Heine, A, Klebe, G. | | 登録日 | 2015-09-14 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.328 Å) | | 主引用文献 | Crystallographic Fragment Screening of an Entire Library
To Be Published
|
|
1BFD
 | | BENZOYLFORMATE DECARBOXYLASE FROM PSEUDOMONAS PUTIDA | | 分子名称: | BENZOYLFORMATE DECARBOXYLASE, CALCIUM ION, MAGNESIUM ION, ... | | 著者 | Hasson, M.S, Muscate, A, Mcleish, M.J, Polovnikova, L.S, Gerlt, J.A, Kenyon, G.L, Petsko, G.A, Ringe, D. | | 登録日 | 1998-04-30 | | 公開日 | 1998-06-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The crystal structure of benzoylformate decarboxylase at 1.6 A resolution: diversity of catalytic residues in thiamin diphosphate-dependent enzymes.
Biochemistry, 37, 1998
|
|
2NYT
 | | The APOBEC2 Crystal Structure and Functional Implications for AID | | 分子名称: | Probable C->U-editing enzyme APOBEC-2, ZINC ION | | 著者 | Prochnow, C, Bransteitter, R, Klein, M, Goodman, M, Chen, X. | | 登録日 | 2006-11-21 | | 公開日 | 2007-01-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The APOBEC-2 crystal structure and functional implications for the deaminase AID.
Nature, 445, 2007
|
|
4MQ5
 | |
5AFW
 | | Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1, ... | | 著者 | Metzger, E, Willmann, D, McMillan, J, Petroll, K, Metzger, P, Gerhardt, S, vonMaessenhausen, A, Schott, A.K, Espejo, A, Eberlin, A, Wohlwend, D, Schuele, K.M, Schleicher, M, Perner, S, Bedford, M.T, Dengjel, J, Flaig, R, Einsle, O, Schuele, R. | | 登録日 | 2015-01-26 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Assembly of Methylated Kdm1A and Chd1 Drives Androgen Receptor-Dependent Transcription and Translocation.
Nat.Struct.Mol.Biol., 23, 2016
|
|
8ORJ
 | | Cryo-EM structure of human tRNA ligase RTCB in complex with human PYROXD1. | | 分子名称: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Loeff, L, Kroupova, A, Asanovic, I, Boneberg, F, Pfleiderer, M.M, Ferdigg, A, Ackle, F, Martinez, J, Jinek, M. | | 登録日 | 2023-04-14 | | 公開日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Mechanistic basis for oxidative stress protection of the human tRNA ligase complex by the oxidoreductase PYROXD1
BioRxiv, 2023
|
|
4OD9
 | | Structure of Cathepsin D with inhibitor N-(3,4-dimethoxybenzyl)-Nalpha-{N-[(3,4-dimethoxyphenyl)acetyl]carbamimidoyl}-D-phenylalaninamide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | 著者 | Graedler, U, Czodrowski, P, Tsaklakidis, C, Klein, M, Maskos, K, Leuthner, B. | | 登録日 | 2014-01-10 | | 公開日 | 2014-08-13 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-based optimization of non-peptidic Cathepsin D inhibitors.
Bioorg.Med.Chem.Lett., 24, 2014
|
|
5DQ2
 | | Endothiapepsin in complex with fragment 48 | | 分子名称: | 1,2-ETHANEDIOL, Endothiapepsin, GLYCEROL, ... | | 著者 | Radeva, N, Uehlein, M, Weiss, M, Heine, A, Klebe, G. | | 登録日 | 2015-09-14 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.514 Å) | | 主引用文献 | Crystallographic Fragment Screening of an Entire Library
To Be Published
|
|
5A3H
 | | 2-DEOXY-2-FLURO-B-D-CELLOBIOSYL/ENZYME INTERMEDIATE COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.8 ANGSTROMS RESOLUTION | | 分子名称: | ENDOGLUCANASE, beta-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-glucopyranose | | 著者 | Davies, G.J, Varrot, A, Dauter, M, Brzozowski, A.M, Schulein, M, Mackenzie, L, Withers, S.G. | | 登録日 | 1998-07-23 | | 公開日 | 1999-07-24 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Snapshots along an enzymatic reaction coordinate: analysis of a retaining beta-glycoside hydrolase.
Biochemistry, 37, 1998
|
|
4QEL
 | | Crystal Structure of Benzoylformate Decarboxylase Mutant H70A | | 分子名称: | 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Benzoylformate decarboxylase, CALCIUM ION, ... | | 著者 | Andrews, F.H, Rogers, M.P, Brodkin, H.R, McLeish, M.J. | | 登録日 | 2014-05-16 | | 公開日 | 2015-05-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.432 Å) | | 主引用文献 | Structural investigation of benzoylformate decarboxylase active site variants
To be Published
|
|
5GAD
 | | RNC-SRP-SR complex early state | | 分子名称: | 1A9L SS, 23S rRNA, 50S ribosomal protein L10, ... | | 著者 | Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. | | 登録日 | 2015-11-24 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon.
Nat Commun, 7, 2016
|
|
5DQ1
 | | Endothiapepsin in complex with fragment 34 | | 分子名称: | 1,2-ETHANEDIOL, 3-[(cyclopropylamino)methyl]-8-ethylquinolin-2(1H)-one, Endothiapepsin, ... | | 著者 | Radeva, N, Uehlein, M, Weiss, M, Heine, A, Klebe, G. | | 登録日 | 2015-09-14 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.489 Å) | | 主引用文献 | Crystallographic Fragment Screening of an Entire Library
To Be Published
|
|
4MZX
 | | Crystal Structure of Benzoylformate Decarboxylase Mutant T377L/A460Y | | 分子名称: | 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Benzoylformate decarboxlyase, CALCIUM ION, ... | | 著者 | Andrews, F.H, McLeish, M.J. | | 登録日 | 2013-09-30 | | 公開日 | 2015-04-01 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.558 Å) | | 主引用文献 | Mechanistic and structural insight to an evolved benzoylformate decarboxylase with enhanced
activity towards pyruvate
To be Published
|
|
5GAG
 | | RNC in complex with SRP-SR in the closed state | | 分子名称: | 1A9L SS, 23S rRNA, 50S ribosomal protein L10, ... | | 著者 | Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. | | 登録日 | 2015-11-26 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon.
Nat Commun, 7, 2016
|
|
2OVW
 | | ENDOGLUCANASE I COMPLEXED WITH CELLOBIOSE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOGLUCANASE I, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Sulzenbacher, G, Davies, G.J, Schulein, M. | | 登録日 | 1997-04-04 | | 公開日 | 1998-04-08 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the endoglucanase I from Fusarium oxysporum: native, cellobiose, and 3,4-epoxybutyl beta-D-cellobioside-inhibited forms, at 2.3 A resolution.
Biochemistry, 36, 1997
|
|
5GAH
 | | RNC in complex with SRP with detached NG domain | | 分子名称: | 1A9L SS, 23S rRNA, 50S ribosomal protein L10, ... | | 著者 | Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. | | 登録日 | 2015-11-26 | | 公開日 | 2016-01-27 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon.
Nat Commun, 7, 2016
|
|
1A3H
 | |
2OWI
 | | Solution structure of the RGS domain from human RGS18 | | 分子名称: | Regulator of G-protein signaling 18 | | 著者 | Higman, V.A, Leidert, M, Bray, J, Elkins, J, Soundararajan, M, Doyle, D.A, Gileadi, C, Phillips, C, Schoch, G, Yang, X, Brockmann, C, Schmieder, P, Diehl, A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC) | | 登録日 | 2007-02-16 | | 公開日 | 2007-02-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
2LRE
 | | The solution structure of the dimeric Acanthaporin | | 分子名称: | Acanthaporin | | 著者 | Michalek, M, Soennichsen, F.D, Wechselberger, R, Dingley, A.J, Wienk, H, Simanski, M, Herbst, R, Lorenzen, I, Marciano-Cabral, F, Gelhaus, C, Groetzinger, J, Leippe, M. | | 登録日 | 2012-03-28 | | 公開日 | 2012-05-02 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and function of a unique pore-forming protein from a pathogenic acanthamoeba.
Nat.Chem.Biol., 9, 2013
|
|
2A3H
 | | CELLOBIOSE COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHERANS AT 2.0 A RESOLUTION | | 分子名称: | ENDOGLUCANASE, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Davies, G.J, Brzozowski, A.M, Andersen, K, Schulein, M. | | 登録日 | 1998-01-22 | | 公開日 | 1999-03-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the Bacillus agaradherans family 5 endoglucanase at 1.6 A and its cellobiose complex at 2.0 A resolution
Biochemistry, 37, 1998
|
|
2PLL
 | | Crystal structure of perdeuterated human arginase I | | 分子名称: | 2(S)-AMINO-6-BORONOHEXANOIC ACID, MANGANESE (II) ION, arginase-1 | | 著者 | Di Costanzo, L, Moulin, M, Haertlein, M, Meilleur, F, Christianson, D.W. | | 登録日 | 2007-04-19 | | 公開日 | 2007-08-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Expression, purification, assay, and crystal structure of perdeuterated human arginase I
Arch.Biochem.Biophys., 465, 2007
|
|
1WLH
 | | Molecular structure of the rod domain of Dictyostelium filamin | | 分子名称: | Gelation factor | | 著者 | Popowicz, G.M, Mueller, R, Noegel, A.A, Schleicher, M, Huber, R, Holak, T.A. | | 登録日 | 2004-06-27 | | 公開日 | 2004-10-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular structure of the rod domain of dictyostelium filamin
J.Mol.Biol., 342, 2004
|
|
4Y3P
 | | Endothiapepsin in complex with fragment 17 | | 分子名称: | 1-(6-methylpyrimidin-4-yl)azepane, Endothiapepsin, GLYCEROL | | 著者 | Radeva, N, Uehlein, M, Weiss, M.S, Heine, A, Klebe, G. | | 登録日 | 2015-02-10 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystallographic Fragment Screening of an Entire Library
To Be Published
|
|
4Y3E
 | | Endothiapepsin in complex with fragment 5 | | 分子名称: | 1H-isoindol-3-amine, ACETATE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Radeva, N, Uehlein, M, Weiss, M.S, Heine, A, Klebe, G. | | 登録日 | 2015-02-10 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Crystallographic Fragment Screening of an Entire Library
To Be Published
|
|
