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PDB: 793 件

5H3A
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Structural analysis of KSHV thymidylate synthase
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ORF70, TOMUDEX
著者Choi, Y.M, Yeo, H.K, Park, Y.W, Lee, J.Y.
登録日2016-10-21
公開日2017-01-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Analysis of Thymidylate Synthase from Kaposi's Sarcoma-Associated Herpesvirus with the Anticancer Drug Raltitrexed.
PLoS ONE, 11, 2016
5H39
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Structural analysis of KSHV thymidylate synthase
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ORF70
著者Choi, Y.M, Yeo, H.K, Park, Y.W, Lee, J.Y.
登録日2016-10-21
公開日2017-01-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis of Thymidylate Synthase from Kaposi's Sarcoma-Associated Herpesvirus with the Anticancer Drug Raltitrexed.
PLoS ONE, 11, 2016
2IS4
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Crystal structure of UvrD-DNA-ADPNP ternary complex
分子名称: 25-MER, DNA helicase II, MAGNESIUM ION, ...
著者Yang, W, Lee, J.Y.
登録日2006-10-16
公開日2007-01-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke.
Cell(Cambridge,Mass.), 127, 2006
2IS1
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Crystal structure of UvrD-DNA-SO4 complex
分子名称: 5'-D(*CP*GP*AP*GP*CP*AP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*TP*GP*CP*TP*CP*GP*TP*TP*TP*TP*TP*TP*T)-3', DNA helicase II, ...
著者Yang, W, Lee, J.Y.
登録日2006-10-16
公開日2007-01-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke.
Cell(Cambridge,Mass.), 127, 2006
2I5S
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Crystal structure of onconase with bound nucleic acid
分子名称: 5'-D(*A*(DU)P*GP*A)-3', P-30 protein
著者Bae, E, Lee, J.E, Raines, R.T, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
登録日2006-08-25
公開日2006-09-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for catalysis by onconase.
J.Mol.Biol., 375, 2008
5HA6
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Crystal structure of human syncytin-1 fusion subunit
分子名称: CHLORIDE ION, Syncytin-1
著者Aydin, H, Lee, J.E.
登録日2015-12-30
公開日2017-08-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.0006 Å)
主引用文献Structural and functional characterization of the human Syncytin 1 fusion protein
To Be Published
3SNV
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Crystal structure of Symfoil-4T Permutation #1: de novo designed beta-trefoil architecture with symmetric primary structure
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, Symfoil-4T/Permutation #1 synthetic protein
著者Blaber, M, Longo, L, Lee, J.
登録日2011-06-29
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Folding pathway redundancy in symmetric protein architecture
To be Published
3SI8
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Human DNA polymerase eta - DNA ternary complex with the 5'T of a CPD in the active site (TT2)
分子名称: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, ...
著者Biertumpfel, C, Zhao, Y, Kondo, Y, Ramon-Maiques, S, Gregory, M, Lee, J.Y, Masutani, C, Lehmann, A.R, Hanaoka, F, Yang, W.
登録日2011-06-17
公開日2011-08-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure and mechanism of human DNA polymerase eta.
Nature, 465, 2010
2GEF
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Crystal structure of a Novel viral protease with a serine/lysine catalytic dyad mechanism
分子名称: Protease VP4
著者Paetzel, M, Feldman, A.R, Lee, J, Delmas, B.
登録日2006-03-20
公開日2006-05-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a novel viral protease with a serine/lysine catalytic dyad mechanism
J.Mol.Biol., 358, 2006
5H38
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Structural analysis of KSHV thymidylate synthase
分子名称: ORF70, PHOSPHATE ION
著者Choi, Y.M, Yeo, H.K, Park, Y.W, Lee, J.Y.
登録日2016-10-21
公開日2017-01-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Analysis of Thymidylate Synthase from Kaposi's Sarcoma-Associated Herpesvirus with the Anticancer Drug Raltitrexed.
PLoS ONE, 11, 2016
2GMK
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Crystal structure of onconase double mutant with spontaneously-assembled (AMP) 4 stack
分子名称: ADENOSINE MONOPHOSPHATE, P-30 protein
著者Bae, E, Lee, J.E, Raines, R.T, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
登録日2006-04-06
公開日2006-04-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis for catalysis by onconase.
J.Mol.Biol., 375, 2008
5F4T
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Crystal structure of the human sperm Izumo1 residues 22-254
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Izumo sperm-egg fusion protein 1
著者Aydin, H, Sultana, A, Lee, J.E.
登録日2015-12-03
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.083 Å)
主引用文献Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex.
Nature, 534, 2016
2HZ9
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Crystal structure of Lys12Val/Asn95Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.70 angstrom resolution.
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-08
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus beta-Strand Interactions
J.Mol.Biol., 371, 2007
5W8N
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Lipid A Disaccharide Synthase (LpxB)-6 solubilizing mutations
分子名称: Lipid-A-disaccharide synthase
著者Bohl, T.E, Aihara, H, Shi, K, Lee, J.K.
登録日2017-06-22
公開日2018-01-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Crystal structure of lipid A disaccharide synthase LpxB from Escherichia coli.
Nat Commun, 9, 2018
7DLS
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Cytochrome P450 (CYP105D18) complex with papaverine
分子名称: 1-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXYISOQUINOLINE, Cytochrome P450 hydroxylase, PROTOPORPHYRIN IX CONTAINING FE
著者Do, H, Lee, J.H.
登録日2020-11-30
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Characterization of high-H 2 O 2 -tolerant bacterial cytochrome P450 CYP105D18: insights into papaverine N-oxidation.
Iucrj, 8, 2021
7DI3
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Cytochrome P450 (CYP105D18) W.T.
分子名称: Cytochrome P450 hydroxylase, PROTOPORPHYRIN IX CONTAINING FE
著者Do, H, Lee, J.H.
登録日2020-11-18
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Characterization of high-H 2 O 2 -tolerant bacterial cytochrome P450 CYP105D18: insights into papaverine N-oxidation.
Iucrj, 8, 2021
2HWA
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Crystal structure of Lys12Thr/Cys117Val mutant of human acidic fibroblast growth factor at 1.65 angstrom resolution.
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-01
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
2HW9
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Crystal structure of Lys12Cys/Cys117Val mutant of human acidic fibroblast Growth factor at 1.60 angstrom resolution.
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-01
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
2HWM
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Crystal structure of Lys12Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.60 angstrom resolution
分子名称: FORMIC ACID, Heparin-binding growth factor 1
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-01
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
3S2P
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Crystal structure of CDK2 with a 2-aminopyrimidine compound
分子名称: (3S,4S)-1-{3-[2-amino-6-(propan-2-yl)pyrimidin-4-yl]-4-hydroxyphenyl}pyrrolidine-3,4-diol, Cyclin-dependent kinase 2
著者Kim, K.-H, Lee, J, Jeong, S.
登録日2011-05-17
公開日2011-07-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of a novel class of 2-aminopyrimidines as CDK1 and CDK2 inhibitors
Bioorg.Med.Chem.Lett., 21, 2011
6K84
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Structure of anti-prion RNA aptamer
分子名称: RNA (25-MER)
著者Mashima, T, Lee, J.H, Hayashi, T, Nagata, T, Kinoshita, M, Katahira, M.
登録日2019-06-11
公開日2020-04-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Development and structural determination of an anti-PrPCaptamer that blocks pathological conformational conversion of prion protein.
Sci Rep, 10, 2020
2JO8
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Solution structure of C-terminal domain of human mammalian sterile 20-like kinase 1 (MST1)
分子名称: Serine/threonine-protein kinase 4
著者Hwang, E, Ryu, K.-S, Paakkonen, K, Guntert, P, Cheong, H.-K, Lim, D.-S, Lee, J.O, Jeon, Y.H, Cheong, C.
登録日2007-02-26
公開日2007-05-15
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway
Proc.Natl.Acad.Sci.Usa, 104, 2007
6KRT
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monodehydroascorbate reductase, MDHAR, from Antarctic hairgrass Deschampsia antarctica
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, monodehydroascorbate reductase
著者Park, A.K, Do, H, Lee, J.H, Kim, H, Choi, W, Kim, I.S, Kim, H.W.
登録日2019-08-22
公開日2020-08-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献monodehydroascorbate reductase, MDHAR, from Antarctic hairgrass Deschampsia antarctica
To Be Published
4J4J
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Crystal structure of the APOBEC3F Vif binding domain
分子名称: DNA dC->dU-editing enzyme APOBEC-3F, ZINC ION
著者Siu, K.K, Sultana, A, Lee, J.E.
登録日2013-02-06
公開日2013-11-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural determinants of HIV-1 Vif susceptibility and DNA binding in APOBEC3F.
Nat Commun, 4, 2013
3FS5
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Crystal structure of Saccharomyces cerevisiae Ygr203w, a homolog of single-domain rhodanese and Cdc25 phosphatase catalytic domain
分子名称: Uncharacterized protein YGR203W
著者Yeo, H.K, Lee, J.Y.
登録日2009-01-09
公開日2009-06-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of Saccharomyces cerevisiae Ygr203w, a homolog of single-domain rhodanese and Cdc25 phosphatase catalytic domain
Proteins, 76, 2009

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件を2024-07-03に公開中

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