7WG3
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![BU of 7wg3 by Molmil](/molmil-images/mine/7wg3) | Structural basis of interleukin-17B receptor in complex with a neutralizing antibody D9 for guiding humanization and affinity maturation for cancer therapy | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of D9 Fab, IL17RB protein, ... | 著者 | Lee, W.H, Chen, X.R, Liu, I.J, Lee, J.H, Hu, C.M, Wu, H.C, Wang, S.K, Lee, W.H, Ma, C. | 登録日 | 2021-12-28 | 公開日 | 2022-11-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation. Cell Rep, 41, 2022
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1L9W
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![BU of 1l9w by Molmil](/molmil-images/mine/1l9w) | CRYSTAL STRUCTURE OF 3-DEHYDROQUINASE FROM SALMONELLA TYPHI COMPLEXED WITH REACTION PRODUCT | 分子名称: | 3-AMINO-4,5-DIHYDROXY-CYCLOHEX-1-ENECARBOXYLATE, 3-dehydroquinate dehydratase aroD | 著者 | Lee, W.H, Perles, L.A, Nagem, R.A.P, Shrive, A.K, Hawkins, A, Sawyer, L, Polikarpov, I. | 登録日 | 2002-03-26 | 公開日 | 2003-03-26 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Comparison of different crystal forms of 3-dehydroquinase from Salmonella typhi and its implication for the enzyme activity. Acta Crystallogr.,Sect.D, 58, 2002
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8U53
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![BU of 8u53 by Molmil](/molmil-images/mine/8u53) | Mechanically activated ion channel OSCA3.1 in nanodiscs | 分子名称: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CSC1-like protein ERD4, PALMITIC ACID, ... | 著者 | Jojoa-Cruz, S, Lee, W.H, Ward, A.B. | 登録日 | 2023-09-12 | 公開日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structure-guided mutagenesis of OSCAs reveals differential activation to mechanical stimuli. Elife, 12, 2024
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6NF4
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![BU of 6nf4 by Molmil](/molmil-images/mine/6nf4) | Structure of zebrafish Otop1 in nanodiscs | 分子名称: | CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, Otopetrin1 | 著者 | Saotome, K, Lee, W.H, Liman, E.R, Ward, A.B. | 登録日 | 2018-12-18 | 公開日 | 2019-06-05 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Structures of the otopetrin proton channels Otop1 and Otop3. Nat.Struct.Mol.Biol., 26, 2019
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6NF6
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![BU of 6nf6 by Molmil](/molmil-images/mine/6nf6) | Structure of chicken Otop3 in nanodiscs | 分子名称: | CHOLESTEROL HEMISUCCINATE, Otopetrin3 | 著者 | Saotome, K, Lee, W.H, Liman, E.R, Ward, A.B. | 登録日 | 2018-12-18 | 公開日 | 2019-06-05 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | Structures of the otopetrin proton channels Otop1 and Otop3. Nat.Struct.Mol.Biol., 26, 2019
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2OHC
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![BU of 2ohc by Molmil](/molmil-images/mine/2ohc) | structural and mutational analysis of tRNA-intron splicing endonuclease from Thermoplasma acidophilum DSM1728 | 分子名称: | tRNA-splicing endonuclease | 著者 | Kim, Y.K, Mizutani, K, Rhee, K.H, Lee, W.H, Park, S.Y, Hwang, K.Y. | 登録日 | 2007-01-10 | 公開日 | 2007-11-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and Mutational Analysis of tRNA Intron-Splicing Endonuclease from Thermoplasma acidophilum DSM 1728: Catalytic Mechanism of tRNA Intron-Splicing Endonucleases J.Bacteriol., 189, 2007
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1MIU
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![BU of 1miu by Molmil](/molmil-images/mine/1miu) | Structure of a BRCA2-DSS1 complex | 分子名称: | Breast Cancer type 2 susceptibility protein, Deleted in split hand/split foot protein 1, MERCURY (II) ION | 著者 | Yang, H, Jeffrey, P.D, Miller, J, Kinnucan, E, Sun, Y, Thoma, N.H, Zheng, N, Chen, P.L, Lee, W.H, Pavletich, N.P. | 登録日 | 2002-08-23 | 公開日 | 2002-09-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA
structure Science, 297, 2002
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1MJE
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![BU of 1mje by Molmil](/molmil-images/mine/1mje) | STRUCTURE OF A BRCA2-DSS1-SSDNA COMPLEX | 分子名称: | 5'-D(P*TP*TP*TP*TP*TP*T)-3', Deleted in split hand/split foot protein 1, breast cancer 2 | 著者 | Yang, H, Jeffrey, P.D, Miller, J, Kinnucan, E, Sun, Y, Thoma, N.H, Zheng, N, Chen, P.L, Lee, W.H, Pavletich, N.P. | 登録日 | 2002-08-27 | 公開日 | 2002-09-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure. Science, 297, 2002
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2OHE
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![BU of 2ohe by Molmil](/molmil-images/mine/2ohe) | Structural and mutational analysis of tRNA-Intron splicing endonuclease from Thermoplasma acidophilum DSM 1728 | 分子名称: | tRNA-splicing endonuclease | 著者 | Kim, Y.K, Mizutani, K, Rhee, K.H, Lee, W.H, Park, S.Y, Hwang, K.Y. | 登録日 | 2007-01-10 | 公開日 | 2007-11-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and Mutational Analysis of tRNA Intron-Splicing Endonuclease from Thermoplasma acidophilum DSM 1728: Catalytic Mechanism of tRNA Intron-Splicing Endonucleases J.Bacteriol., 189, 2007
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8T57
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![BU of 8t57 by Molmil](/molmil-images/mine/8t57) | Structure of mechanically activated ion channel OSCA2.3 in peptidiscs | 分子名称: | CHOLESTEROL, CSC1-like protein HYP1, PALMITIC ACID | 著者 | Jojoa-Cruz, S, Burendei, B, Lee, W.H, Ward, A.B. | 登録日 | 2023-06-12 | 公開日 | 2023-12-27 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structure of mechanically activated ion channel OSCA2.3 reveals mobile elements in the transmembrane domain. Structure, 32, 2024
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8T56
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![BU of 8t56 by Molmil](/molmil-images/mine/8t56) | Structure of mechanically activated ion channel OSCA1.2 in peptidiscs | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Burendei, B, Jojoa-Cruz, S, Lee, W.H, Ward, A.B. | 登録日 | 2023-06-12 | 公開日 | 2023-12-27 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structure of mechanically activated ion channel OSCA2.3 reveals mobile elements in the transmembrane domain. Structure, 32, 2024
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3KKL
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7N5F
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![BU of 7n5f by Molmil](/molmil-images/mine/7n5f) | Structure of Mechanosensitive Ion Channel Flycatcher1 Protomer in 'Down' conformation in GDN | 分子名称: | Mechanosensitive ion channel Flycatcher1, PALMITIC ACID | 著者 | Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B. | 登録日 | 2021-06-05 | 公開日 | 2022-02-16 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1. Nat Commun, 13, 2022
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7N5D
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![BU of 7n5d by Molmil](/molmil-images/mine/7n5d) | Composite Structure of Mechanosensitive Ion Channel Flycatcher1 in GDN | 分子名称: | Mechanosensitive ion channel Flycatcher1, PALMITIC ACID | 著者 | Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B. | 登録日 | 2021-06-05 | 公開日 | 2022-02-16 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1. Nat Commun, 13, 2022
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7N5G
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![BU of 7n5g by Molmil](/molmil-images/mine/7n5g) | Structure of Mechanosensitive Ion Channel Flycatcher1 Protomer in 'Up' conformation in GDN | 分子名称: | Mechanosensitive ion channel Flycatcher1, PALMITIC ACID | 著者 | Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B. | 登録日 | 2021-06-05 | 公開日 | 2022-02-16 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1. Nat Commun, 13, 2022
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7N5E
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![BU of 7n5e by Molmil](/molmil-images/mine/7n5e) | Structure of Mechanosensitive Ion Channel Flycatcher1 in GDN | 分子名称: | Mechanosensitive ion channel Flycatcher1, PALMITIC ACID | 著者 | Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B. | 登録日 | 2021-06-05 | 公開日 | 2022-02-16 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1. Nat Commun, 13, 2022
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3NGL
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![BU of 3ngl by Molmil](/molmil-images/mine/3ngl) | Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum | 分子名称: | Bifunctional protein folD, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Sung, M.W, Lee, W.H, Hwang, K.Y. | 登録日 | 2010-06-12 | 公開日 | 2011-04-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase from Thermoplasma acidophilum Biochem.Biophys.Res.Commun., 406, 2011
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3NGX
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1GMZ
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![BU of 1gmz by Molmil](/molmil-images/mine/1gmz) | |
2G3Y
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![BU of 2g3y by Molmil](/molmil-images/mine/2g3y) | Crystal structure of the human small GTPase GEM | 分子名称: | GTP-binding protein GEM, GUANOSINE-5'-DIPHOSPHATE | 著者 | Ugochukwu, E, Soundararajan, M, Elkins, J, Gileadi, C, Schoch, G, Sobott, F, Fedorov, O, Bray, J, Pantic, N, Berridge, G, Burgess, N, Lee, W.H, Turnbull, A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC) | 登録日 | 2006-02-21 | 公開日 | 2006-04-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the human small GTPase GEM To be Published
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1ZV4
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![BU of 1zv4 by Molmil](/molmil-images/mine/1zv4) | Structure of the Regulator of G-Protein Signaling 17 (RGSZ2) | 分子名称: | Regulator of G-protein signaling 17 | 著者 | Schoch, G.A, Jansson, A, Elkins, J.M, Haroniti, A, Niesen, F.H, Bunkoczi, G, Lee, W.H, Turnbull, A.P, Yang, X, Sundstrom, M, Arrowsmith, C, Edwards, A, Marsden, B, Gileadi, O, Ball, L, von Delft, F, Doyle, D.A, Structural Genomics Consortium (SGC) | 登録日 | 2005-06-01 | 公開日 | 2005-06-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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