5KUK
 
 | | Crystal Structure of Inward Rectifier Kir2.2 K62W Mutant | | 分子名称: | ATP-sensitive inward rectifier potassium channel 12, DECYL-BETA-D-MALTOPYRANOSIDE, POTASSIUM ION | | 著者 | Lee, S.-J, Ren, F, Heyman, S, Yuan, P, Nichols, C.G. | | 登録日 | 2016-07-13 | | 公開日 | 2016-08-10 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids.
J.Gen.Physiol., 148, 2016
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5KUM
 | | Crystal Structure of Inward Rectifier Kir2.2 K62W Mutant In Complex with PIP2 | | 分子名称: | ATP-sensitive inward rectifier potassium channel 12, DECYL-BETA-D-MALTOPYRANOSIDE, POTASSIUM ION, ... | | 著者 | Lee, S.-J, Ren, F, Heyman, S, Yuan, P, Nichols, C.G. | | 登録日 | 2016-07-13 | | 公開日 | 2016-08-10 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids.
J.Gen.Physiol., 148, 2016
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6O8E
 | | Crystal structure of UvrB bound to duplex DNA with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*GP*CP*CP*GP*TP*AP*TP*GP*CP*CP*AP*AP*TP*CP*TP*AP*GP*AP*GP*C)-3'), ... | | 著者 | Lee, S.-J, Verdine, G.L. | | 登録日 | 2019-03-10 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System.
Res, 2019, 2019
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6O8H
 | | Crystal structure of UvrB mutant bound to duplex DNA | | 分子名称: | CHLORIDE ION, DNA (5'-D(P*AP*GP*CP*GP*CP*GP*AP*TP*GP*GP*AP*GP*A)-3'), DNA (5'-D(P*CP*CP*AP*TP*CP*GP*CP*GP*CP*TP*AP*CP*C)-3'), ... | | 著者 | Lee, S.-J, Verdine, G.L. | | 登録日 | 2019-03-10 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System.
Res, 2019, 2019
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6O8G
 | | Crystal structure of UvrB bound to fully duplex DNA | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*GP*GP*TP*AP*GP*CP*GP*CP*GP*AP*TP*GP*GP*AP*GP*A)-3'), ... | | 著者 | Lee, S.-J, Sung, R.-J, Verdine, G.L. | | 登録日 | 2019-03-10 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System.
Res, 2019, 2019
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6O8F
 | | Crystal structure of UvrB bound to duplex DNA | | 分子名称: | ACETATE ION, CHLORIDE ION, DNA (5'-D(*GP*CP*CP*GP*TP*AP*TP*GP*CP*CP*AP*AP*TP*CP*TP*AP*GP*AP*GP*C)-3'), ... | | 著者 | Lee, S.-J, Verdine, G.L. | | 登録日 | 2019-03-10 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System.
Res, 2019, 2019
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6OQA
 | | Crystal structure of CEP250 bound to FKBP12 in the presence of FK506-like novel natural product | | 分子名称: | (3R,4E,7E,10R,11S,12R,13S,16R,17R,24aS)-11,17-dihydroxy-10,12,16-trimethyl-3-[(2R)-1-phenylbutan-2-yl]-6,9,10,11,12,13,14,15,16,17,22,23,24,24a-tetradecahydro-3H-13,17-epoxypyrido[2,1-c][1,4]oxazacyclohenicosine-1,18,19(21H)-trione, 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ... | | 著者 | Lee, S.-J, Shigdel, U.K, Townson, S.A, Verdine, G.L. | | 登録日 | 2019-04-26 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5WPL
 | | KRas G12V, bound to GppNHp and miniprotein 225-11 | | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | | 著者 | Lee, S.-J, Shim, S.Y, McGee, J.H, Verdine, G.L. | | 登録日 | 2017-08-05 | | 公開日 | 2018-01-03 | | 最終更新日 | 2018-03-14 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Exceptionally high-affinity Ras binders that remodel its effector domain.
J. Biol. Chem., 293, 2018
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5WPM
 | | KRas G12V, bound to GppNHp and miniprotein 225-11(A30R) | | 分子名称: | GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Lee, S.-J, Shim, S.Y, McGee, J.H, Verdine, G.L. | | 登録日 | 2017-08-05 | | 公開日 | 2018-01-03 | | 最終更新日 | 2018-03-14 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Exceptionally high-affinity Ras binders that remodel its effector domain.
J. Biol. Chem., 293, 2018
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6M84
 | | Crystal structure of cKir2.2 force open mutant in complex with PI(4,5)P2 | | 分子名称: | ATP-sensitive inward rectifier potassium channel 12, DODECYL-BETA-D-MALTOSIDE, POTASSIUM ION, ... | | 著者 | Lee, S.-J, Ren, F, Yuan, P, Nichols, C.G. | | 登録日 | 2018-08-21 | | 公開日 | 2019-09-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels.
J.Gen.Physiol., 152, 2020
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6M85
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6M86
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3U7K
 | | Crystal structures of the Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors | | 分子名称: | (S)-N-(cyclopentylmethyl)-N-(2-(hydroxyamino)-2-oxoethyl)-2-(3-(2-methoxyphenyl)ureido)-3,3-dimethylbutanamide, Peptide deformylase, ZINC ION | | 著者 | Lee, S.J, Lee, S.-J, Lee, S.K, Yoon, H.-J, Lee, H.H, Kim, K.K, Lee, B.J, Suh, S.W. | | 登録日 | 2011-10-14 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Acta Crystallogr.,Sect.D, 68, 2012
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3U7N
 | | Crystal structures of the Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors | | 分子名称: | N-((2R,4S)-2-butyl-5-methyl-4-(3-(5-methylpyridin-2-yl)ureido)-3-oxohexyl)-N-hydroxyformamide, Peptide deformylase, ZINC ION | | 著者 | Lee, S.J, Lee, S.-J, Lee, S.K, Yoon, H.-J, Lee, H.H, Kim, K.K, Lee, B.J, Suh, S.W. | | 登録日 | 2011-10-14 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Acta Crystallogr.,Sect.D, 68, 2012
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4WBU
 | | prion peptide | | 分子名称: | PrP peptide | | 著者 | Yu, L, Lee, S.-J, Yee, V. | | 登録日 | 2014-09-03 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
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4W5P
 | | Prp peptide | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, PrP peptide | | 著者 | Yu, L, Lee, S.-J, Yee, V. | | 登録日 | 2014-08-18 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.151 Å) | | 主引用文献 | Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
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4W67
 | | Crystal structure of Prp peptide | | 分子名称: | PrP peptide | | 著者 | Yu, L, Lee, S.-J, Yee, V. | | 登録日 | 2014-08-20 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.001 Å) | | 主引用文献 | Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
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4W71
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3U7L
 | | Crystal structures of the Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors | | 分子名称: | (S)-N-(cyclopentylmethyl)-2-(3-(3,5-difluorophenyl)ureido)-N-(2-(hydroxyamino)-2-oxoethyl)-3,3-dimethylbutanamide, Peptide deformylase, ZINC ION | | 著者 | Lee, S.J, Lee, S.-J, Lee, S.K, Yoon, H.-J, Lee, H.H, Kim, K.K, Lee, B.J, Suh, S.W. | | 登録日 | 2011-10-14 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Acta Crystallogr.,Sect.D, 68, 2012
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3U7M
 | | Crystal structures of the Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors | | 分子名称: | N-((2R,4S)-2-butyl-4-(3-(2-fluorophenyl)ureido)-5-methyl-3-oxohexyl)-N-hydroxyformamide, Peptide deformylase, ZINC ION | | 著者 | Lee, S.J, Lee, S.-J, Lee, S.K, Yoon, H.-J, Lee, H.H, Kim, K.K, Lee, B.J, Suh, S.W. | | 登録日 | 2011-10-14 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Acta Crystallogr.,Sect.D, 68, 2012
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4TUT
 | | Structure of a Prion peptide | | 分子名称: | Prion peptide: GLY-GLY-TYR-MET-LEU-GLY | | 著者 | Yu, L, Lee, S.-J, Yee, V. | | 登録日 | 2014-06-24 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | | 主引用文献 | Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
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4UBY
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4UBZ
 | | Crystal structure of a prion peptide | | 分子名称: | SODIUM ION, prion peptide | | 著者 | Yu, L, Lee, S.-J, Yee, V. | | 登録日 | 2014-08-13 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.001 Å) | | 主引用文献 | Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
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4W5M
 | | Prp peptide | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, PrP peptide | | 著者 | Yu, L, Lee, S.-J, Yee, V. | | 登録日 | 2014-08-18 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
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4W5Y
 | | Crystal structure of Prp pepttide | | 分子名称: | Prp peptide | | 著者 | Yu, L, Lee, S.-J, Yee, V. | | 登録日 | 2014-08-19 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.122 Å) | | 主引用文献 | Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
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