2Z25
| Thr110Val dihydroorotase from E. coli | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | Authors: | Lee, M, Maher, M.J, Guss, J.M. | Deposit date: | 2007-05-17 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State Biochemistry, 46, 2007
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2Z27
| Thr109Ser dihydroorotase from E. coli | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | Authors: | Lee, M, Maher, M.J, Guss, J.M. | Deposit date: | 2007-05-17 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State Biochemistry, 46, 2007
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2Z2A
| Thr109Gly dihydroorotase from E. coli | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | Authors: | Lee, M, Maher, M.J, Guss, J.M. | Deposit date: | 2007-05-17 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State Biochemistry, 46, 2007
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2EG7
| The crystal structure of E. coli dihydroorotase complexed with HDDP | Descriptor: | 2-OXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4,6-DICARBOXYLIC ACID, Dihydroorotase, ZINC ION | Authors: | Lee, M, Maher, M.J, Guss, J.M. | Deposit date: | 2007-02-28 | Release date: | 2007-07-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of Ligand-free and Inhibitor Complexes of Dihydroorotase from Escherichia coli: Implications for Loop Movement in Inhibitor Design J.Mol.Biol., 370, 2007
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2EG6
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2EG8
| The crystal structure of E. coli dihydroorotase complexed with 5-fluoroorotic acid | Descriptor: | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, ZINC ION | Authors: | Lee, M, Maher, M.J, Guss, J.M. | Deposit date: | 2007-02-28 | Release date: | 2007-07-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of Ligand-free and Inhibitor Complexes of Dihydroorotase from Escherichia coli: Implications for Loop Movement in Inhibitor Design J.Mol.Biol., 370, 2007
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1WVK
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3KQI
| crystal structure of PHF2 PHD domain complexed with H3K4Me3 peptide | Descriptor: | CHLORIDE ION, GLYCEROL, H3K4Me3 peptide, ... | Authors: | Wen, H, Li, J.Z, Song, T, Lu, M, Lee, M. | Deposit date: | 2009-11-17 | Release date: | 2010-02-02 | Last modified: | 2019-02-13 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation. J.Biol.Chem., 285, 2010
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1N0W
| Crystal structure of a RAD51-BRCA2 BRC repeat complex | Descriptor: | 1,2-ETHANEDIOL, ARTIFICIAL GLY-SER-MSE-GLY PEPTIDE, Breast cancer type 2 susceptibility protein, ... | Authors: | Pellegrini, L, Yu, D.S, Lo, T, Anand, S, Lee, M, Blundell, T.L, Venkitaraman, A.R. | Deposit date: | 2002-10-15 | Release date: | 2002-11-27 | Last modified: | 2020-01-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Insights into DNA recombination from the structure of a RAD51-BRCA2 complex Nature, 420, 2002
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6DLN
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7SMR
| Cryo-EM structure of Torpedo acetylcholine receptor in complex with carbachol, desensitized state | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E. | Deposit date: | 2021-10-26 | Release date: | 2022-03-09 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Structural mechanism of muscle nicotinic receptor desensitization and block by curare. Nat.Struct.Mol.Biol., 29, 2022
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7SMM
| Cryo-EM structure of Torpedo acetylcholine receptor in apo form | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E. | Deposit date: | 2021-10-26 | Release date: | 2022-03-09 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structural mechanism of muscle nicotinic receptor desensitization and block by curare. Nat.Struct.Mol.Biol., 29, 2022
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7SMQ
| Cryo-EM structure of Torpedo acetylcholine receptor in apo form with added cholesterol | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E. | Deposit date: | 2021-10-26 | Release date: | 2022-03-09 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural mechanism of muscle nicotinic receptor desensitization and block by curare. Nat.Struct.Mol.Biol., 29, 2022
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7SMS
| Cryo-EM structure of Torpedo acetylcholine receptor in complex with d-tubocurarine | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor subunit alpha, ... | Authors: | Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E. | Deposit date: | 2021-10-26 | Release date: | 2022-03-09 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Structural mechanism of muscle nicotinic receptor desensitization and block by curare. Nat.Struct.Mol.Biol., 29, 2022
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7SMT
| Cryo-EM structure of Torpedo acetylcholine receptor in complex with d-tubocurarine and carbachol | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E. | Deposit date: | 2021-10-26 | Release date: | 2022-03-09 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (2.56 Å) | Cite: | Structural mechanism of muscle nicotinic receptor desensitization and block by curare. Nat.Struct.Mol.Biol., 29, 2022
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4RNZ
| Structure of Helicobacter pylori Csd3 from the hexagonal crystal | Descriptor: | Conserved hypothetical secreted protein, GLYCEROL, NICKEL (II) ION, ... | Authors: | An, D.R, Kim, H.S, Kim, J, Im, H.N, Yoon, H.J, Yoon, J.Y, Jang, J.Y, Hesek, D, Lee, M, Mobashery, S, Kim, S.-J, Lee, B.I, Suh, S.W. | Deposit date: | 2014-10-27 | Release date: | 2015-03-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure of Csd3 from Helicobacter pylori, a cell shape-determining metallopeptidase. Acta Crystallogr.,Sect.D, 71, 2015
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4RNY
| Structure of Helicobacter pylori Csd3 from the orthorhombic crystal | Descriptor: | Conserved hypothetical secreted protein, GLYCEROL, SULFATE ION, ... | Authors: | An, D.R, Kim, H.S, Kim, J, Im, H.N, Yoon, H.J, Yoon, J.Y, Jang, J.Y, Hesek, D, Lee, M, Mobashery, S, Kim, S.-J, Lee, B.I, Suh, S.W. | Deposit date: | 2014-10-27 | Release date: | 2015-03-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of Csd3 from Helicobacter pylori, a cell shape-determining metallopeptidase. Acta Crystallogr.,Sect.D, 71, 2015
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6LCI
| Solution structure of mdaA-1 domain | Descriptor: | mdaA-1 | Authors: | Nguyen, T.A, Le, S, Lee, M, Fan, J.S, Yang, D, Yan, J, Jedd, G. | Deposit date: | 2019-11-19 | Release date: | 2020-11-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Fungal Wound Healing through Instantaneous Protoplasmic Gelation. Curr.Biol., 31, 2021
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2RGT
| Crystal Structure of Lhx3 LIM domains 1 and 2 with the binding domain of Isl1 | Descriptor: | Fusion of LIM/homeobox protein Lhx3, linker, Insulin gene enhancer protein ISL-1, ... | Authors: | Bhati, M, Lee, M, Guss, J.M, Matthews, J.M. | Deposit date: | 2007-10-05 | Release date: | 2008-08-12 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes. Embo J., 27, 2008
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6XFM
| Molecular structure of the core of amyloid-like fibrils formed by residues 111-214 of FUS | Descriptor: | RNA-binding protein FUS | Authors: | Tycko, R, Lee, M, Ghosh, U, Thurber, K, Kato, M. | Deposit date: | 2020-06-15 | Release date: | 2020-10-07 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.62 Å) | Cite: | Molecular structure and interactions within amyloid-like fibrils formed by a low-complexity protein sequence from FUS. Nat Commun, 11, 2020
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6Z3B
| Low resolution structure of RgNanOx | Descriptor: | CITRIC ACID, Gfo/Idh/MocA family oxidoreductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Naismith, J.H, Lee, M. | Deposit date: | 2020-05-19 | Release date: | 2020-07-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Uncovering a novel molecular mechanism for scavenging sialic acids in bacteria. J.Biol.Chem., 295, 2020
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1FMQ
| Cyclo-butyl-bis-furamidine complexed with dCGCGAATTCGCG | Descriptor: | 2,5-BIS{[4-(N-CYCLOBUTYLDIAMINOMETHYL)PHENYL]}FURAN, 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION | Authors: | Simpson, I.J, Lee, M, Kumar, A, Boykin, D.W, Neidle, S. | Deposit date: | 2000-08-18 | Release date: | 2000-09-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | DNA minor groove interactions and the biological activity of 2,5-bis-[4-(N-alkylamidino)phenyl] furans Bioorg.Med.Chem.Lett., 10, 2000
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1FMS
| Structure of complex between cyclohexyl-bis-furamidine and d(CGCGAATTCGCG) | Descriptor: | 2,5-BIS{[4-(N-CYCLOHEXYLDIAMINOMETHYL)PHENYL]}FURAN, 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION | Authors: | Simpson, I.J, Lee, M, Kumar, A, Boykin, D.W, Neidle, S. | Deposit date: | 2000-08-18 | Release date: | 2000-09-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | DNA minor groove interactions and the biological activity of 2,5-bis-[4-(N-alkylamidino)phenyl] furans Bioorg.Med.Chem.Lett., 10, 2000
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7QAJ
| ZK002 with Anti-angiogenic and Anti-inflamamtory Properties | Descriptor: | SULFATE ION, Snaclec clone 2100755 alpha, Snaclec clone 2100755 beta | Authors: | Wong, W.Y, Chan, B.D, Muk Lan Lee, M, Dai, X, Tsim, K.W.K, Hsiao, W.L.W, Li, M, Li, X.Y, Tai, W.C.S. | Deposit date: | 2021-11-17 | Release date: | 2023-06-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Isolation and characterization of ZK002, a novel dual function snake venom protein from Deinagkistrodon acutus with anti-angiogenic and anti-inflammatory properties. Front Pharmacol, 14, 2023
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1FUR
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