5T1J
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![BU of 5t1j by Molmil](/molmil-images/mine/5t1j) | Crystal Structure of the Tbox DNA binding domain of the transcription factor T-bet | Descriptor: | DNA, T-box transcription factor TBX21 | Authors: | Liu, C.F, Brandt, G.S, Hoang, Q, Hwang, E.S, Naumova, N, Lazarevic, V, Dekker, J, Glimcher, L.H, Ringe, D, Petsko, G.A. | Deposit date: | 2016-08-19 | Release date: | 2016-10-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.947 Å) | Cite: | Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites. Proc.Natl.Acad.Sci.USA, 113, 2016
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7QZV
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![BU of 7qzv by Molmil](/molmil-images/mine/7qzv) | Hm-AMP2 | Descriptor: | Hm-AMP2 | Authors: | Grafskaia, E.N, Pavlova, E.R, Latsis, I.A, Malakhova, M.V, Lavrenova, V.N, Ivchenkov, D.V, Bashkirov, P.V, Kot, E.F, Mineev, K.S, Arseniev, A.S, Klinov, D.V, Lazarev, V.N. | Deposit date: | 2022-02-01 | Release date: | 2022-11-23 | Method: | SOLUTION NMR | Cite: | Non-toxic antimicrobial peptide Hm-AMP2 from leech metagenome proteins identified by the gradient-boosting approach Materials, 224, 2022
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7QZW
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![BU of 7qzw by Molmil](/molmil-images/mine/7qzw) | Hm-AMP8 | Descriptor: | Hm-AMP8 | Authors: | Grafskaia, E.N, Pavlova, E.R, Latsis, I.A, Malakhova, M.V, Lavrenova, V.N, Ivchenkov, D.V, Bashkirov, P.V, Kot, E.F, Mineev, K.S, Arseniev, A.S, Klinov, D.V, Lazarev, V.N. | Deposit date: | 2022-02-01 | Release date: | 2023-02-15 | Method: | SOLUTION NMR | Cite: | The study of the interaction of cationic peptides from a medical leech with blood components as a first step to the systemic use of antimicrobial peptides for therapy of infectious diseases To Be Published
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8BBU
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![BU of 8bbu by Molmil](/molmil-images/mine/8bbu) | Crystal structure of medical leech destabilase (high salt) | Descriptor: | GLYCEROL, Lysozyme, MALONATE ION, ... | Authors: | Marin, E, Bukhdruker, S, Manuvera, V, Kornilov, D, Zinovev, E, Bobrovsky, P, Lazarev, V, Borshchevskiy, V. | Deposit date: | 2022-10-14 | Release date: | 2023-02-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structural insights into thrombolytic activity of destabilase from medicinal leech. Sci Rep, 13, 2023
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8BBW
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![BU of 8bbw by Molmil](/molmil-images/mine/8bbw) | Crystal structure of medical leech destabilase (low salt) | Descriptor: | CHLORIDE ION, GLYCEROL, Lysozyme | Authors: | Marin, E, Bukhdruker, S, Manuvera, V, Kornilov, D, Zinovev, E, Bobrovsky, P, Lazarev, V, Borshchevskiy, V. | Deposit date: | 2022-10-14 | Release date: | 2023-02-08 | Last modified: | 2024-08-21 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural insights into thrombolytic activity of destabilase from medicinal leech. Sci Rep, 13, 2023
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6RRO
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![BU of 6rro by Molmil](/molmil-images/mine/6rro) | |
6RRL
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![BU of 6rrl by Molmil](/molmil-images/mine/6rrl) | |
6RSM
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![BU of 6rsm by Molmil](/molmil-images/mine/6rsm) | Solution NMR structure of the peptide 12530 from medicinal leech Hirudo medicinalis in dodecylphosphocholine micelles | Descriptor: | peptide 12530 | Authors: | Talyzina, I.A, Nadezhdin, K.D, Grafskaia, E.N, Arseniev, A.S, Lazarev, V.N. | Deposit date: | 2019-05-21 | Release date: | 2019-07-24 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Medicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens. Eur.J.Med.Chem., 180, 2019
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