1ATG
 
 | | AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, PERIPLASMIC MOLYBDATE-BINDING PROTEIN, ... | | 著者 | Lawson, D.M, Pau, R.N, Williams, C.E.M, Mitchenall, L.A. | | 登録日 | 1997-08-14 | | 公開日 | 1998-10-14 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Ligand size is a major determinant of specificity in periplasmic oxyanion-binding proteins: the 1.2 A resolution crystal structure of Azotobacter vinelandii ModA.
Structure, 6, 1998
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1THT
 | | STRUCTURE OF A MYRISTOYL-ACP-SPECIFIC THIOESTERASE FROM VIBRIO HARVEYI | | 分子名称: | THIOESTERASE | | 著者 | Lawson, D.M, Derewenda, U, Serre, L, Ferri, S, Szitter, R, Wei, Y, Meighen, E.A, Derewenda, Z.S. | | 登録日 | 1994-04-19 | | 公開日 | 1995-06-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of a myristoyl-ACP-specific thioesterase from Vibrio harveyi.
Biochemistry, 33, 1994
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1E84
 | | Cytochrome c' from Alcaligenes xylosoxidans - reduced structure | | 分子名称: | CYTOCHROME C', HEME C | | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | | 登録日 | 2000-09-15 | | 公開日 | 2000-11-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase
Embo J., 19, 2000
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1E86
 | | Cytochrome c' from Alcaligenes xylosoxidans - reduced structure with CO bound to distal side of heme | | 分子名称: | CARBON MONOXIDE, CYTOCHROME C', HEME C | | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | | 登録日 | 2000-09-15 | | 公開日 | 2000-11-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase
Embo J., 19, 2000
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1E83
 | | Cytochrome c' from Alcaligenes xylosoxidans - oxidized structure | | 分子名称: | CYTOCHROME C', HEME C | | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | | 登録日 | 2000-09-15 | | 公開日 | 2000-11-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase
Embo J., 19, 2000
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1E85
 | | Cytochrome c' from Alcaligenes xylosoxidans - reduced structure with NO bound to proximal side of heme | | 分子名称: | CYTOCHROME C', HEME C, NITRIC OXIDE | | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | | 登録日 | 2000-09-15 | | 公開日 | 2000-11-06 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase.
Embo J., 19, 2000
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6TVP
 | | Structure of Mycobacterium smegmatis alpha-maltose-1-phosphate synthase GlgM | | 分子名称: | Alpha-maltose-1-phosphate synthase, SODIUM ION | | 著者 | Syson, K, Stevenson, C.E.M, Lawson, D.M, Bornemann, S. | | 登録日 | 2020-01-10 | | 公開日 | 2020-04-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the Mycobacterium smegmatis alpha-maltose-1-phosphate synthase GlgM.
Acta Crystallogr.,Sect.F, 76, 2020
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9FOY
 | | Ternary complex of a Mycobacterium tuberculosis DNA gyrase core fusion with DNA and the inhibitor AMK32b | | 分子名称: | (1~{R})-2-[4-[[4-bromanyl-3,5-bis(fluoranyl)phenyl]methylamino]cyclohexyl]-1-(6-methoxy-1,5-naphthyridin-4-yl)ethanol, (1~{S})-2-[4-[[4-bromanyl-3,5-bis(fluoranyl)phenyl]methylamino]cyclohexyl]-1-(6-methoxy-1,5-naphthyridin-4-yl)ethanol, DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*G)-3'), ... | | 著者 | Kokot, M, Hrast, M, Feng, L, Mitchenall, L.A, Lawson, D.M, Maxwell, A, Minovski, N, Anderluh, M. | | 登録日 | 2024-06-12 | | 公開日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Unraveling the Mycobacterium tuberculosis DNA gyrase-DNA-NBTI complex
To be published
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1QGU
 | | NITROGENASE MO-FE PROTEIN FROM KLEBSIELLA PNEUMONIAE, DITHIONITE-REDUCED STATE | | 分子名称: | 1,2-ETHANEDIOL, 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CHLORIDE ION, ... | | 著者 | Mayer, S.M, Lawson, D.M, Gormal, C.A, Roe, S.M, Smith, B.E. | | 登録日 | 1999-05-06 | | 公開日 | 1999-11-01 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | New insights into structure-function relationships in nitrogenase: A 1.6 A resolution X-ray crystallographic study of Klebsiella pneumoniae MoFe-protein.
J.Mol.Biol., 292, 1999
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8QA9
 | | Crystal structure of the RK2 plasmid encoded co-complex of the C-terminally truncated transcriptional repressor protein KorB complexed with the partner repressor protein KorA bound to OA-DNA | | 分子名称: | DNA (5'-D(*TP*GP*TP*TP*TP*AP*GP*CP*TP*AP*AP*AP*CP*A)-3'), SULFATE ION, Transcriptional repressor protein KorB, ... | | 著者 | McLean, T.C, Mundy, J.E.A, Lawson, D.M, Le, T.B.K. | | 登録日 | 2023-08-22 | | 公開日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of the RK2 plasmid encoded co-complex of the C-terminally truncated transcriptional repressor protein KorB complexed with the partner repressor protein KorA bound to OA-DNA
To Be Published
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8QA8
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3ZMD
 | | Crystal structure of AbsC, a MarR family transcriptional regulator from Streptomyces coelicolor | | 分子名称: | 1,2-ETHANEDIOL, 2-HYDROXYBENZOIC ACID, CHLORIDE ION, ... | | 著者 | Stevenson, C.E.M, Kock, H, Mootien, S, Davies, S.C, Bibb, M.J, Lawson, D.M. | | 登録日 | 2013-02-07 | | 公開日 | 2013-02-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal Structure of Absc, a Marr Family Transcriptional Regulator from Streptomyces Coelicolor
To be Published
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8PFC
 | | Crystal structure of binary complex between Aster yellows witches'-broom phytoplasma effector SAP05 and the zinc finger domain of SPL5 from Arabidopsis thaliana | | 分子名称: | Sequence-variable mosaic (SVM) signal sequence domain-containing protein, Squamosa promoter-binding-like protein 5, ZINC ION | | 著者 | Huang, W, Liu, Q, Maqbool, A, Stevenson, C.E.M, Lawson, D.M, Kamoun, S, Hogenhout, S.A. | | 登録日 | 2023-06-15 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Bimodular architecture of bacterial effector SAP05 that drives ubiquitin-independent targeted protein degradation.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8PFD
 | | Crystal structure of binary complex between Aster yellows witches'-broom phytoplasma effector SAP05 and the von Willebrand Factor Type A domain of the proteasomal ubiquitin receptor Rpn10 from Arabidopsis thaliana | | 分子名称: | 26S proteasome non-ATPase regulatory subunit 4 homolog, Sequence-variable mosaic (SVM) signal sequence domain-containing protein | | 著者 | Huang, W, Liu, Q, Maqbool, A, Stevenson, C.E.M, Lawson, D.M, Kamoun, S, Hogenhout, S.A. | | 登録日 | 2023-06-15 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Bimodular architecture of bacterial effector SAP05 that drives ubiquitin-independent targeted protein degradation.
Proc.Natl.Acad.Sci.USA, 120, 2023
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6HQ8
 | | Bacterial beta-1,3-oligosaccharide phosphorylase from GH149 with laminarihexaose bound at a surface site | | 分子名称: | 1,2-ETHANEDIOL, BICINE, Beta-1,3-oligosaccharide phosphorylase, ... | | 著者 | Kuhaudomlarp, S, Stevenson, C.E.M, Lawson, D.M, Field, R.A. | | 登録日 | 2018-09-24 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The structure of a GH149 beta-(1 → 3) glucan phosphorylase reveals a new surface oligosaccharide binding site and additional domains that are absent in the disaccharide-specific GH94 glucose-beta-(1 → 3)-glucose (laminaribiose) phosphorylase.
Proteins, 87, 2019
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6HQ6
 | | Bacterial beta-1,3-oligosaccharide phosphorylase from GH149 | | 分子名称: | 1,2-ETHANEDIOL, BICINE, Bacterial beta-1,3-oligosaccharide phosphorylase, ... | | 著者 | Kuhaudomlarp, S, Stevenson, C.E.M, Lawson, D.M, Field, R.A. | | 登録日 | 2018-09-24 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The structure of a GH149 beta-(1 → 3) glucan phosphorylase reveals a new surface oligosaccharide binding site and additional domains that are absent in the disaccharide-specific GH94 glucose-beta-(1 → 3)-glucose (laminaribiose) phosphorylase.
Proteins, 87, 2019
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3ZST
 | | GlgE isoform 1 from Streptomyces coelicolor with alpha-cyclodextrin bound | | 分子名称: | 1,2-ETHANEDIOL, Cyclohexakis-(1-4)-(alpha-D-glucopyranose), PUTATIVE GLUCANOHYDROLASE PEP1A GLGE ISOFORM 1 | | 著者 | Syson, K, Stevenson, C.E.M, Rejzek, M, Fairhurst, S.A, Nair, A, Bruton, C.J, Field, R.A, Chater, K.F, Lawson, D.M, Bornemann, S. | | 登録日 | 2011-06-30 | | 公開日 | 2011-09-14 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of a Streptomyces Maltosyltransferase Glge: A Homologue of a Genetically Validated Anti-Tuberculosis Target.
J.Biol.Chem., 286, 2011
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3ZSS
 | | Apo form of GlgE isoform 1 from Streptomyces coelicolor | | 分子名称: | PUTATIVE GLUCANOHYDROLASE PEP1A | | 著者 | Syson, K, Stevenson, C.E.M, Rejzek, M, Fairhurst, S.A, Nair, A, Bruton, C.J, Field, R.A, Chater, K.F, Lawson, D.M, Bornemann, S. | | 登録日 | 2011-06-30 | | 公開日 | 2011-09-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of a Streptomyces Maltosyltransferase Glge: A Homologue of a Genetically Validated Anti-Tuberculosis Target.
J.Biol.Chem., 286, 2011
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3ZPL
 | | Crystal structure of Sco3205, a MarR family transcriptional regulator from Streptomyces coelicolor, in complex with DNA | | 分子名称: | 5'-D(*AP*AP*AP*GP*AP*TP*TP*GP*AP*GP*AP*TP*CP*TP *CP*AP*AP*TP*CP*TP*TP*DT)-3', PHOSPHATE ION, PUTATIVE MARR-FAMILY TRANSCRIPTIONAL REPRESSOR | | 著者 | Stevenson, C.E.M, Assaad, A, Lawson, D.M. | | 登録日 | 2013-02-28 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Investigation of DNA Sequence Recognition by a Streptomycete Marr Family Transcriptional Regulator Through Surface Plasmon Resonance and X-Ray Crystallography.
Nucleic Acids Res., 41, 2013
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3ZQL
 | | DNA-bound form of TetR-like repressor SimR | | 分子名称: | 5'-D(*DTP*TP*CP*GP*TP*AP*CP*GP*CP*CP*GP*TP*AP*DCP *GP*AP*A)-3', 5'-D(*DTP*TP*CP*GP*TP*AP*CP*GP*GP*CP*GP*TP*AP*DCP *GP*AP*A)-3', PUTATIVE REPRESSOR SIMREG2 | | 著者 | Le, T.B.K, Schumacher, M.A, Lawson, D.M, Brennan, R.G, Buttner, M.J. | | 登録日 | 2011-06-10 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | The Crystal Structure of the Tetr Family Transcriptional Repressor Simr Bound to DNA and the Role of a Flexible N-Terminal Extension in Minor Groove Binding.
Nucleic Acids Res., 39, 2011
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8BV0
 | | Binary complex between the NB-ARC domain from the Tomato immune receptor NRC1 and the SPRY domain-containing effector SS15 from the potato cyst nematode | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, NRC1, Truncated secreted SPRY domain-containing protein 15 (Fragment) | | 著者 | Contreras, M.P, Pai, H, Muniyandi, S, Toghani, A, Lawson, D.M, Tumtas, Y, Duggan, C, Yuen, E.L.H, Stevenson, C.E.M, Harant, A, Wu, C.H, Bozkurt, T.O, Kamoun, S, Derevnina, L. | | 登録日 | 2022-12-01 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | Resurrection of plant disease resistance proteins via helper NLR bioengineering.
Sci Adv, 9, 2023
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8BN6
 | | Pseudomonas aeruginosa DNA gyrase B 24kDa ATPase subdomain complexed with EBL3021 | | 分子名称: | 2-[[3,4-bis(chloranyl)-5-methyl-1~{H}-pyrrol-2-yl]carbonylamino]-4-morpholin-4-yl-1,3-benzothiazole-6-carboxylic acid, CALCIUM ION, DNA gyrase subunit B | | 著者 | Durcik, M, Zega, A, Zidar, N, Ilas, J, Tomasic, T, Masic, L.P, Mundy, J.E.A, Stevenson, C.E.M, Burton, N, Lawson, D.M, Maxwell, A, Kikelj, D. | | 登録日 | 2022-11-12 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus .
J.Med.Chem., 66, 2023
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1H9M
 | | Two crystal structures of the cytoplasmic molybdate-binding protein ModG suggest a novel cooperative binding mechanism and provide insights into ligand-binding specificity. PEG-grown form with molybdate bound | | 分子名称: | MOLYBDATE ION, MOLYBDENUM-BINDING-PROTEIN | | 著者 | Delarbre, L, Stevenson, C.E.M, White, D.J, Mitchenall, L.A, Pau, R.N, Lawson, D.M. | | 登録日 | 2001-03-13 | | 公開日 | 2001-05-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Two Crystal Structures of the Cytoplasmic Molybdate-Binding Protein Modg Suggest a Novel Cooperative Binding Mechanism and Provide Insights Into Ligand-Binding Specificity
J.Mol.Biol., 308, 2001
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1H4D
 | | Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis protein MobA | | 分子名称: | CITRIC ACID, LITHIUM ION, MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS PROTEIN A | | 著者 | Guse, A, Stevenson, C.E.M, Kuper, J, Buchanan, G, Schwarz, G, Mendel, R.R, Lawson, D.M, Palmer, T. | | 登録日 | 2003-02-26 | | 公開日 | 2003-05-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis Protein Moba
J.Biol.Chem., 278, 2003
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1H4E
 | | Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis protein MobA | | 分子名称: | CITRIC ACID, LITHIUM ION, MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS PROTEIN A | | 著者 | Guse, A, Stevenson, C.E.M, Kuper, J, Buchanan, G, Schwarz, G, Mendel, R.R, Lawson, D.M, Palmer, T. | | 登録日 | 2003-02-26 | | 公開日 | 2003-05-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis Protein Moba
J.Biol.Chem., 278, 2003
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