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PDB: 148 件
3STI
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BU of 3sti by Molmil
Crystal structure of the protease domain of DegQ from Escherichia coli
分子名称: Protease degQ
著者Sawa, J, Malet, H, Krojer, T, Canellas, F, Ehrmann, M, Clausen, T.
登録日2011-07-11
公開日2011-07-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
J.Biol.Chem., 286, 2011
5MZU
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BU of 5mzu by Molmil
Crystal structure of the myosin chaperone UNC-45 from C. elegans (alternative conformation)
分子名称: UNC-45
著者Hellerschmied, D, Gazda, L, Clausen, T.
登録日2017-02-01
公開日2018-02-14
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献UFD-2 is an adaptor-assisted E3 ligase targeting unfolded proteins.
Nat Commun, 9, 2018
3STJ
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BU of 3stj by Molmil
Crystal structure of the protease + PDZ1 domain of DegQ from Escherichia coli
分子名称: Protease degQ, peptide (UNK)
著者Sawa, J, Malet, H, Krojer, T, Canellas, F, Ehrmann, M, Clausen, T.
登録日2011-07-11
公開日2011-07-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
J.Biol.Chem., 286, 2011
5HBN
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BU of 5hbn by Molmil
ClpC N-terminal domain with bound phospho-arginine
分子名称: ACETATE ION, Negative regulator of genetic competence ClpC/MecB, SULFATE ION, ...
著者Suskiewicz, M.J, Clausen, T.
登録日2016-01-01
公開日2016-10-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Arginine phosphorylation marks proteins for degradation by a Clp protease.
Nature, 539, 2016
3FXQ
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BU of 3fxq by Molmil
Crystal structure of the LysR-type transcriptional regulator TsaR
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, FORMIC ACID, ...
著者Monferrer, D, Tralau, T, Kertesz, M.A, Kikhney, A, Svergun, D, Uson, I.
登録日2009-01-21
公開日2010-01-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural studies on the full-length LysR-type regulator TsaR from Comamonas testosteroni T-2 reveal a novel open conformation of the tetrameric LTTR fold
Mol.Microbiol., 75, 2010
3FXR
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BU of 3fxr by Molmil
Crystal structure of TsaR in complex with sulfate
分子名称: ASCORBIC ACID, GLYCEROL, LysR type regulator of tsaMBCD, ...
著者Monferrer, D, Tralau, T, Kertesz, M.A, Kikhney, A, Svergun, D, Uson, I.
登録日2009-01-21
公開日2010-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural studies on the full-length LysR-type regulator TsaR from Comamonas testosteroni T-2 reveal a novel open conformation of the tetrameric LTTR fold
Mol.Microbiol., 75, 2010
3NUM
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BU of 3num by Molmil
Substrate induced remodeling of the active site regulates HtrA1 activity
分子名称: Serine protease HTRA1
著者Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M.
登録日2010-07-07
公開日2011-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Nat.Struct.Mol.Biol., 18, 2011
3NZI
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BU of 3nzi by Molmil
Substrate induced remodeling of the active site regulates HtrA1 activity
分子名称: Citrate synthase, Serine protease HTRA1
著者Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M.
登録日2010-07-16
公開日2011-02-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Nat.Struct.Mol.Biol., 18, 2011
5D4W
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BU of 5d4w by Molmil
Crystal structure of Hsp104
分子名称: ADENOSINE-5'-DIPHOSPHATE, Putative heat shock protein
著者Heuck, A, Schitter-Sollner, S, Clausen, T.
登録日2015-08-09
公開日2016-12-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structural basis for the disaggregase activity and regulation of Hsp104.
Elife, 5, 2016
7AA4
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BU of 7aa4 by Molmil
Structure of ClpC1-NTD bound to a CymA analogue
分子名称: Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue
著者Meinhart, A, Morreale, F.E, Kaiser, M, Clausen, T.
登録日2020-09-03
公開日2021-08-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
7ABR
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BU of 7abr by Molmil
Cryo-EM structure of B. subtilis ClpC (DWB mutant) hexamer bound to a substrate polypeptide
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Negative regulator of genetic competence ClpC/MecB, ...
著者Morreale, F.E, Meinhart, A, Haselbach, D, Clausen, T.
登録日2020-09-08
公開日2021-10-06
最終更新日2022-07-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
6FH1
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BU of 6fh1 by Molmil
Protein arginine kinase McsB in the apo state
分子名称: 1,2-ETHANEDIOL, FORMIC ACID, IMIDAZOLE, ...
著者Suskiewicz, M.J, Heuck, A, Vu, L.D, Clausen, T.
登録日2018-01-12
公開日2019-02-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of McsB, a protein kinase for regulated arginine phosphorylation.
Nat.Chem.Biol., 15, 2019
6QDJ
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BU of 6qdj by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
分子名称: 1,4-BUTANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ADENOSINE-5'-DIPHOSPHATE, ...
著者Meinhart, A, Clausen, T, Arnese, R.
登録日2019-01-02
公開日2019-10-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.884 Å)
主引用文献Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
8BRH
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BU of 8brh by Molmil
Co-crystal structure of She4 with Myo4 peptide
分子名称: KLLA0E16699p, Myo4 peptide (LYS-PHE-ILE-VAL-SER-HIS-TYR)
著者Arnese, R, Gudino, R, Meinhart, A, Clausen, T.
登録日2022-11-23
公開日2024-06-05
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献UNC-45 assisted myosin folding depends on a conserved FX 3 HY motif implicated in Freeman Sheldon Syndrome.
Nat Commun, 15, 2024
8BRG
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BU of 8brg by Molmil
Crystal structure of She4
分子名称: KLLA0E16699p
著者Gudino, R, Arnese, R, Meinhart, A, Clausen, T.
登録日2022-11-23
公開日2024-06-05
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献UNC-45 assisted myosin folding depends on a conserved FX 3 HY motif implicated in Freeman Sheldon Syndrome.
Nat Commun, 15, 2024
6QDL
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BU of 6qdl by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
分子名称: UNC-45
著者Meinhart, A, Clausen, T, Hellerschmied, D.
登録日2019-01-02
公開日2019-10-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.929 Å)
主引用文献Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
6QDM
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BU of 6qdm by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
分子名称: UNC-45,UNC-45
著者Meinhart, A, Clausen, T, Hellerschmied, D.
登録日2019-01-02
公開日2019-10-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
2OD1
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BU of 2od1 by Molmil
Solution structure of the MYND domain from human AML1-ETO
分子名称: Protein CBFA2T1, ZINC ION
著者Liu, Y.Z, Chen, W, Gaudet, J, Cheney, M.D, Roudaia, L, Cierpicki, T, Klet, R.C, Hartman, K, Laue, T.M, Speck, N.A, Bushweller, J.H.
登録日2006-12-21
公開日2007-06-19
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.
Cancer Cell, 11, 2007
3CS0
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BU of 3cs0 by Molmil
Crystal structure of DegP24
分子名称: Periplasmic serine endoprotease DegP, pentapeptide
著者Krojer, T, Sawa, J, Schaefer, E, Saibil, H.R, Ehrmann, M, Clausen, T.
登録日2008-04-08
公開日2008-05-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the regulated protease and chaperone function of DegP
Nature, 453, 2008
2ODD
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BU of 2odd by Molmil
Solution structure of the MYND domain from AML1-ETO complexed with SMRT, a corepressor
分子名称: Protein CBFA2T1, SMRT, ZINC ION
著者Liu, Y.Z, Chen, W, Gaudet, J, Cheney, M.D, Roudaia, L, Cierpicki, T, Klet, R.C, Hartman, K, Laue, T.M, Speck, N.A, Bushweller, J.H.
登録日2006-12-22
公開日2007-06-19
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.
Cancer Cell, 11, 2007
6QDK
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BU of 6qdk by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
分子名称: UNC-45,UNC-45
著者Meinhart, A, Clausen, T, Hellerschmied, D.
登録日2019-01-02
公開日2019-10-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
7SNV
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BU of 7snv by Molmil
H. neapolitanus carboxysomal rubisco/CsoSCA-peptide (1-50)complex
分子名称: Carboxysome shell carbonic anhydrase, Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain
著者Blikstad, C, Dugan, E, Laughlin, T.G, Liu, M, Shoemaker, S, Remis, J, Savage, D.F.
登録日2021-10-28
公開日2023-05-03
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.07 Å)
主引用文献Identification of a carbonic anhydrase-Rubisco complex within the alpha-carboxysome.
Proc.Natl.Acad.Sci.USA, 120, 2023
7SMK
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BU of 7smk by Molmil
H. neapolitanus carboxysomal rubisco/CsoSCA-peptide (1-50)complex
分子名称: Carboxysome shell carbonic anhydrase, Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain
著者Blikstad, C, Dugan, E, Laughlin, T.G, Liu, M, Shoemaker, S, Remis, J, Savage, D.F.
登録日2021-10-26
公開日2023-05-24
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (1.98 Å)
主引用文献Identification of a carbonic anhydrase-Rubisco complex within the alpha-carboxysome.
Proc.Natl.Acad.Sci.USA, 120, 2023
1SOZ
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BU of 1soz by Molmil
Crystal Structure of DegS protease in complex with an activating peptide
分子名称: Protease degS, activating peptide
著者Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
登録日2004-03-16
公開日2004-06-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
8B9O
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BU of 8b9o by Molmil
Structure of the C-terminal domain of ClpC2 from Mycobacterium smegmatis
分子名称: Clp amino terminal domain protein, phospho-arginine
著者Meinhart, A, Hoi, D.M, Clausen, T.
登録日2022-10-06
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Cell, 186, 2023

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