8RXB
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![BU of 8rxb by Molmil](/molmil-images/mine/8rxb) | |
6Z3R
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![BU of 6z3r by Molmil](/molmil-images/mine/6z3r) | Structure of SMG1-8-9 kinase complex bound to UPF1-LSQ | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Langer, L.M, Gat, Y, Conti, E. | 登録日 | 2020-05-21 | 公開日 | 2020-06-24 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity. Elife, 9, 2020
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7PW9
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![BU of 7pw9 by Molmil](/molmil-images/mine/7pw9) | Human SMG1-9 kinase complex bound to AMPPNP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
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7PW8
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![BU of 7pw8 by Molmil](/molmil-images/mine/7pw8) | Human SMG1-8-9 kinase complex bound to AMPPNP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
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7PW4
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![BU of 7pw4 by Molmil](/molmil-images/mine/7pw4) | Human SMG1-8-9 kinase complex bound to a SMG1 inhibitor | 分子名称: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
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7PW5
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![BU of 7pw5 by Molmil](/molmil-images/mine/7pw5) | |
7PW6
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![BU of 7pw6 by Molmil](/molmil-images/mine/7pw6) | Human SMG1-8-9 kinase complex bound to a SMG1 inhibitor - SMG1 body | 分子名称: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, INOSITOL HEXAKISPHOSPHATE, Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1 | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
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7PW7
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![BU of 7pw7 by Molmil](/molmil-images/mine/7pw7) | Human SMG1-9 kinase complex bound to a SMG1 inhibitor | 分子名称: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
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6RO1
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![BU of 6ro1 by Molmil](/molmil-images/mine/6ro1) | X-ray crystal structure of the MTR4 NVL complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Exosome RNA helicase MTR4, ... | 著者 | Lingaraju, M, Langer, L.M, Basquin, J, Falk, S, Conti, E. | 登録日 | 2019-05-10 | 公開日 | 2019-07-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | 主引用文献 | The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs. Nat Commun, 10, 2019
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4IYE
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![BU of 4iye by Molmil](/molmil-images/mine/4iye) | Crystal structure of AdTx1 (rho-Da1a) from eastern green mamba (Dendroaspis angusticeps) | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Toxin AdTx1 | 著者 | Stura, E.A, Vera, L, Maiga, A.A, Marchetti, C, Lorphelin, A, Bellanger, L, Servant, D, Gilles, N. | 登録日 | 2013-01-28 | 公開日 | 2013-05-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.951 Å) | 主引用文献 | Crystallization of recombinant green mamba rho-Da1a toxin during a lyophilization procedure and its structure determination. Acta Crystallogr.,Sect.F, 69, 2013
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