8PP5
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8PP4
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8PP2
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8PP3
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8RXB
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7PW8
| Human SMG1-8-9 kinase complex bound to AMPPNP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
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7PW4
| Human SMG1-8-9 kinase complex bound to a SMG1 inhibitor | 分子名称: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
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7PW9
| Human SMG1-9 kinase complex bound to AMPPNP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
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7PW5
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7PW6
| Human SMG1-8-9 kinase complex bound to a SMG1 inhibitor - SMG1 body | 分子名称: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, INOSITOL HEXAKISPHOSPHATE, Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1 | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
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7PW7
| Human SMG1-9 kinase complex bound to a SMG1 inhibitor | 分子名称: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
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6Z3R
| Structure of SMG1-8-9 kinase complex bound to UPF1-LSQ | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Langer, L.M, Gat, Y, Conti, E. | 登録日 | 2020-05-21 | 公開日 | 2020-06-24 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity. Elife, 9, 2020
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5J0F
| Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P4/5 | 分子名称: | GLYCEROL, Superoxide dismutase [Cu-Zn],OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn] | 著者 | Wang, H, Lang, L, Logan, D, Danielsson, J, Oliveberg, M. | 登録日 | 2016-03-28 | 公開日 | 2017-02-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Tricking a Protein To Swap Strands. J. Am. Chem. Soc., 138, 2016
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4XCR
| Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant I35A | 分子名称: | Superoxide dismutase [Cu-Zn] | 著者 | Wang, H, Logan, D.T, Danielsson, J, Mu, X, Binolfi, A, Theillet, F, Bekei, B, Lang, L, Wennerstrom, H, Selenko, P, Oliveberg, M. | 登録日 | 2014-12-18 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.602 Å) | 主引用文献 | Thermodynamics of protein destabilization in live cells. Proc. Natl. Acad. Sci. U.S.A., 112, 2015
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5J07
| Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P1/2 | 分子名称: | Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn] | 著者 | Wang, H, Lang, L, Logan, D, Danielsson, J, Oliveberg, M. | 登録日 | 2016-03-27 | 公開日 | 2017-02-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Tricking a Protein To Swap Strands. J. Am. Chem. Soc., 138, 2016
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5J0C
| Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P2/3 | 分子名称: | Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn] | 著者 | Wang, H, Lang, L, Logan, D, Danielsson, J, Oliveberg, M. | 登録日 | 2016-03-28 | 公開日 | 2017-02-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Tricking a Protein To Swap Strands. J. Am. Chem. Soc., 138, 2016
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5J0G
| Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P7/8 | 分子名称: | OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn] | 著者 | Wang, H, Lang, L, Logan, D, Danielsson, J, Oliveberg, M. | 登録日 | 2016-03-28 | 公開日 | 2017-02-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Tricking a Protein To Swap Strands. J. Am. Chem. Soc., 138, 2016
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4BCY
| Monomeric Human Cu,Zn Superoxide dismutase, mutation H43F | 分子名称: | CADMIUM ION, CHLORIDE ION, COPPER (II) ION, ... | 著者 | Awad, W, Saraboji, K, Danielsson, J, Lang, L, Kurnik, M, Marklund, S.L, Oliveberg, M, Logan, D.T. | 登録日 | 2012-10-03 | 公開日 | 2013-02-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.272 Å) | 主引用文献 | Global Structural Motions from the Strain of a Single Hydrogen Bond. Proc.Natl.Acad.Sci.USA, 110, 2013
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4BCZ
| Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form. | 分子名称: | SUPEROXIDE DISMUTASE [CU-ZN] | 著者 | Saraboji, K, Awad, W, Danielsson, J, Lang, L, Kurnik, M, Marklund, S.L, Oliveberg, M, Logan, D.T. | 登録日 | 2012-10-03 | 公開日 | 2013-02-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Global Structural Motions from the Strain of a Single Hydrogen Bond. Proc.Natl.Acad.Sci.USA, 110, 2013
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4BD4
| Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F | 分子名称: | GLYCEROL, SUPEROXIDE DISMUTASE [CU-ZN] | 著者 | Awad, W, Saraboji, K, Danielsson, J, Lang, L, Kurnik, M, Marklund, S.L, Oliveberg, M, Logan, D.T. | 登録日 | 2012-10-04 | 公開日 | 2013-02-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Global Structural Motions from the Strain of a Single Hydrogen Bond. Proc.Natl.Acad.Sci.USA, 110, 2013
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2BCE
| CHOLESTEROL ESTERASE FROM BOS TAURUS | 分子名称: | CHOLESTEROL ESTERASE | 著者 | Chen, J.C.-H, Miercke, L.J.W, Krucinski, J, Starr, J.R, Saenz, G, Wang, X, Spilburg, C.A, Lange, L.G, Ellsworth, J.L, Stroud, R.M. | 登録日 | 1998-01-28 | 公開日 | 1999-02-02 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of bovine pancreatic cholesterol esterase at 1.6 A: novel structural features involved in lipase activation. Biochemistry, 37, 1998
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9G8O
| human 40S ribosome bound by a SKI238-exosome complex | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Koegel, A, Keidel, A, Loukeri, M.J, Kuhn, C.C, Langer, L.M, Schaefer, I.B, Conti, E. | 登録日 | 2024-07-23 | 公開日 | 2024-10-16 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of mRNA decay by the human exosome-ribosome supercomplex. Nature, 2024
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9G8M
| human 80S ribosome bound by a SKI2-exosome complex | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Koegel, A, Keidel, A, Loukeri, M.J, Kuhn, C.C, Langer, L.M, Schaefer, I.B, Conti, E. | 登録日 | 2024-07-23 | 公開日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of mRNA decay by the human exosome-ribosome supercomplex. Nature, 2024
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9G8N
| 80S-bound human Ski2-exosome complex | 分子名称: | CrPV-IRES RNA, DIS3-like exonuclease 1, Exosome complex component CSL4, ... | 著者 | Koegel, A, Keidel, A, Loukeri, M.J, Kuhn, C.C, Langer, L.M, Schaefer, I.B, Conti, E. | 登録日 | 2024-07-23 | 公開日 | 2024-10-16 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of mRNA decay by the human exosome-ribosome supercomplex. Nature, 2024
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9G8P
| 40S-bound human SKI2-exosome complex | 分子名称: | CrPV-IRES RNA, DIS3-like exonuclease 1, Exosome complex component CSL4, ... | 著者 | Koegel, A, Keidel, A, Loukeri, M.J, Kuhn, C.C, Langer, L.M, Schaefer, I.B, Conti, E. | 登録日 | 2024-07-23 | 公開日 | 2024-10-16 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Structural basis of mRNA decay by the human exosome-ribosome supercomplex. Nature, 2024
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