9BAJ
 
 | | Crystal structure of GDP-bound human K-RAS in a covalent complex with aryl sulfonyl fluoride compounds. | | Descriptor: | 3-(dioxo-lambda~6~-sulfanyl)-N-phenylbenzene-1-sulfonamide, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | | Authors: | Landgraf, A.D, Brenner, R.J, Ghozayel, M.K, Bum-Erdene, K, Gonzalez-Gutierrez, G, Meroueh, S. | | Deposit date: | 2024-04-04 | | Release date: | 2025-04-09 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Small-Molecule KRAS Inhibitors by Tyrosine Covalent Bond Formation.
Chemmedchem, 2025
|
|
9BAK
 | | Crystal structure of GDP-bound human K-RAS in a covalent complex with aryl sulfonyl fluoride compounds. | | Descriptor: | 3-[bis(oxidanylidene)-$l^{5}-sulfanyl]-~{N}-pyridazin-3-yl-benzenesulfonamide, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | | Authors: | Landgraf, A.D, Brenner, R.J, Ghozayel, M.K, Bum-Erdene, K, Gonzalez-Gutierrez, G, Meroueh, S. | | Deposit date: | 2024-04-04 | | Release date: | 2025-04-09 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Small-Molecule KRAS Inhibitors by Tyrosine Covalent Bond Formation.
Chemmedchem, 2025
|
|
9BAI
 | | Crystal structure of GDP-bound human K-RAS in a covalent complex with aryl sulfonyl fluoride compounds. | | Descriptor: | 3-[bis(oxidanylidene)-$l^{5}-sulfanyl]-~{N}-pyridin-4-yl-benzenesulfonamide, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | | Authors: | Landgraf, A.D, Brenner, R.J, Ghozayel, M.K, Bum-Erdene, K, Gonzalez-Gutierrez, G, Meroueh, S. | | Deposit date: | 2024-04-04 | | Release date: | 2025-04-09 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Small-Molecule KRAS Inhibitors by Tyrosine Covalent Bond Formation.
Chemmedchem, 2025
|
|
8FJI
 | | Crystal structure of RalA in a covalent complex with SOF-367 | | Descriptor: | 8-[fluoro(dihydroxy)-lambda~4~-sulfanyl]-N-(2-methoxypyridin-3-yl)-2,3-dihydro-1,4-benzodioxine-5-sulfonamide, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Landgraf, A.D, Yeh, I.-J, Bum-Erdene, K, Gonzalez-Gutierrez, G, Meroueh, S. | | Deposit date: | 2022-12-19 | | Release date: | 2023-12-06 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Exploring Covalent Bond Formation at Tyr-82 for Inhibition of Ral GTPase Activation.
Chemmedchem, 18, 2023
|
|
8FJH
 | | Crystal structure of RalA in a covalent complex with SOF-531 | | Descriptor: | 8-[bis(oxidanyl)-$l^{3}-sulfanyl]-~{N}-(3-fluoranyl-5-methoxy-phenyl)-2,3-dihydro-1,4-benzodioxine-5-sulfonamide, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Landgraf, A.D, Yeh, I.-J, Bum-Erdene, K, Gonzalez-Gutierrez, G, Meroueh, S. | | Deposit date: | 2022-12-19 | | Release date: | 2023-12-06 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Exploring Covalent Bond Formation at Tyr-82 for Inhibition of Ral GTPase Activation.
Chemmedchem, 18, 2023
|
|
