5MTD
 
 | | Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T - crystal form II | | Descriptor: | NICKEL (II) ION, Putative uncharacterized protein orf60T, TRIETHYLENE GLYCOL, ... | | Authors: | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | | Deposit date: | 2017-01-09 | | Release date: | 2017-09-20 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation.
Sci Rep, 7, 2017
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2UYW
 | | Crystal structure of Xenavidin | | Descriptor: | BIOTIN, FORMIC ACID, XENAVIDIN | | Authors: | Helppolainen, S.H, Maatta, J.A.E, Airenne, T.T, Johnson, M.S, Kulomaa, M.S, Nordlund, H.R. | | Deposit date: | 2007-04-20 | | Release date: | 2008-05-27 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural and Functional Characteristics of Xenavidin, the First Frog Avidin from Xenopus Tropicalis.
Bmc Struct.Biol., 9, 2009
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3EKK
 | | Insulin receptor kinase complexed with an inhibitor | | Descriptor: | 2-[(2-{[1-(N,N-dimethylglycyl)-5-methoxy-1H-indol-6-yl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-6-fluoro-N-methylbenzamide, Insulin receptor | | Authors: | Chamberlain, S, Atkins, C, Deanda, F, Dumble, M, Gerding, R, Groy, A, Korenchuk, S, Kumar, R, Lei, H, Mook, R, Moorthy, G, Redman, A, Rowland, J, Sabbatini, P, Shewchuk, L. | | Deposit date: | 2008-09-19 | | Release date: | 2008-12-23 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase.
Bioorg.Med.Chem.Lett., 19, 2009
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3ELJ
 | | Jnk1 complexed with a bis-anilino-pyrrolopyrimidine inhibitor. | | Descriptor: | 2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide, Mitogen-activated protein kinase 8 | | Authors: | Chamberlain, S, Atkins, C, Deanda, F, Dumble, M, Gerding, R, Groy, A, Korenchuk, S, Kumar, R, Lei, H, Mook, R, Moorthy, G, Redman, A, Rowland, J, Shewchuk, L, Vicentini, G, Mosley, J. | | Deposit date: | 2008-09-22 | | Release date: | 2008-12-30 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity.
Bioorg.Med.Chem.Lett., 19, 2009
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3EKN
 | | Insulin receptor kinase complexed with an inhibitor | | Descriptor: | 2-fluoro-6-{[2-({2-methoxy-4-[4-(1-methylethyl)piperazin-1-yl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide, Insulin receptor | | Authors: | Chamberlain, S, Atkins, C, Deanda, F, Dumble, M, Gerding, R, Groy, A, Korenchuk, S, Kumar, R, Lei, H, Mook, R, Moorthy, G, Redman, A, Rowland, J, Shewchuk, L. | | Deposit date: | 2008-09-19 | | Release date: | 2008-12-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity.
Bioorg.Med.Chem.Lett., 19, 2009
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1JB1
 | | Lactobacillus casei HprK/P Bound to Phosphate | | Descriptor: | HPRK PROTEIN, PHOSPHATE ION | | Authors: | Fieulaine, S, Morera, S, Poncet, S, Monedero, V, Gueguen-Chaignon, V, Galinier, A, Janin, J, Deutscher, J, Nessler, S. | | Deposit date: | 2001-06-01 | | Release date: | 2001-08-08 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | X-ray structure of HPr kinase: a bacterial protein kinase with a P-loop nucleotide-binding domain.
EMBO J., 20, 2001
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1KKL
 | | L.casei HprK/P in complex with B.subtilis HPr | | Descriptor: | CALCIUM ION, HprK protein, PHOSPHOCARRIER PROTEIN HPR | | Authors: | Fieulaine, S, Morera, S, Poncet, S, Galinier, A, Janin, J, Deutscher, J, Nessler, S. | | Deposit date: | 2001-12-10 | | Release date: | 2002-08-28 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | X-ray structure of a bifunctional protein kinase in complex with its protein substrate HPr.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1KKM
 | | L.casei HprK/P in complex with B.subtilis P-Ser-HPr | | Descriptor: | CALCIUM ION, HprK protein, PHOSPHATE ION, ... | | Authors: | Fieulaine, S, Morera, S, Poncet, S, Galinier, A, Janin, J, Deutscher, J, Nessler, S. | | Deposit date: | 2001-12-10 | | Release date: | 2002-08-28 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | X-ray structure of a bifunctional protein kinase in complex with its protein substrate HPr.
Proc.Natl.Acad.Sci.USA, 99, 2002
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4EB0
 | | Crystal structure of Leaf-branch compost bacterial cutinase homolog | | Descriptor: | LCC, THIOCYANATE ION | | Authors: | Sulaiman, S, You, D.J, Eiko, K, Koga, Y, Kanaya, S. | | Deposit date: | 2012-03-23 | | Release date: | 2013-03-27 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure of Leaf-branch compost bacterial cutinase homolog
To be Published
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4JE6
 | | Crystal structure of a human-like mitochondrial peptide deformylase | | Descriptor: | Peptide deformylase 1A, chloroplastic/mitochondrial, ZINC ION | | Authors: | Fieulaine, S, Meinnel, T, Giglione, C. | | Deposit date: | 2013-02-26 | | Release date: | 2014-02-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart.
Acta Crystallogr.,Sect.D, 70, 2014
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4JE8
 | | Crystal structure of a human-like mitochondrial peptide deformylase in complex with Met-Ala-Ser | | Descriptor: | Peptide deformylase 1A, chloroplastic/mitochondrial, ZINC ION, ... | | Authors: | Fieulaine, S, Meinnel, T, Giglione, C. | | Deposit date: | 2013-02-26 | | Release date: | 2014-02-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart.
Acta Crystallogr.,Sect.D, 70, 2014
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3SVL
 | | Structural basis of the improvement of ChrR - a multi-purpose enzyme | | Descriptor: | CALCIUM ION, FLAVIN MONONUCLEOTIDE, protein yieF | | Authors: | Poulain, S, Eswaramoorthy, S, Hienerwadel, R, Bremond, N, Sylvester, M.D, Zhang, Y.B, Van Der Lelie, D, Berthomieu, C, Matin, A.C. | | Deposit date: | 2011-07-12 | | Release date: | 2012-05-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of ChrR-A Quinone Reductase with the Capacity to Reduce Chromate.
Plos One, 7, 2012
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4JE7
 | | Crystal structure of a human-like mitochondrial peptide deformylase in complex with actinonin | | Descriptor: | ACTINONIN, Peptide deformylase 1A, chloroplastic/mitochondrial, ... | | Authors: | Fieulaine, S, Meinnel, T, Giglione, C. | | Deposit date: | 2013-02-26 | | Release date: | 2014-02-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart.
Acta Crystallogr.,Sect.D, 70, 2014
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3PN3
 | | Crystal structure of Arabidopsis thaliana petide deformylase 1B (AtPDF1B) in complex with inhibitor 21 | | Descriptor: | Peptide deformylase 1B, chloroplastic, ZINC ION, ... | | Authors: | Fieulaine, S, Meinnel, T, Giglione, C. | | Deposit date: | 2010-11-18 | | Release date: | 2011-06-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Trapping conformational States along ligand-binding dynamics of Peptide deformylase: the impact of induced fit on enzyme catalysis.
Plos Biol., 9, 2011
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3O3J
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3M6P
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3PN4
 | | Crystal structure of Arabidopsis thaliana petide deformylase 1B (AtPDF1B) in complex with actinonin (crystallized in PEG-550-MME) | | Descriptor: | ACTINONIN, Peptide deformylase 1B, chloroplastic, ... | | Authors: | Fieulaine, S, Meinnel, T, Giglione, C. | | Deposit date: | 2010-11-18 | | Release date: | 2011-06-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Trapping conformational States along ligand-binding dynamics of Peptide deformylase: the impact of induced fit on enzyme catalysis.
Plos Biol., 9, 2011
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3PN2
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3PN6
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3PN5
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1ZY1
 | | X-ray structure of peptide deformylase from Arabidopsis thaliana (AtPDF1A) in complex with Met-Ala-Ser | | Descriptor: | Peptide deformylase, mitochondrial, ZINC ION, ... | | Authors: | Fieulaine, S, Juillan-Binard, C, Serero, A, Dardel, F, Giglione, C, Meinnel, T, Ferrer, J.-L. | | Deposit date: | 2005-06-09 | | Release date: | 2005-09-27 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms
J.Biol.Chem., 280, 2005
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2KVL
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1ZXZ
 | | X-ray structure of peptide deformylase from Arabidopsis thaliana (AtPDF1A); crystals grown in PEG-5000 MME as precipitant | | Descriptor: | Peptide deformylase, mitochondrial, ZINC ION | | Authors: | Fieulaine, S, Juillan-Binard, C, Serero, A, Dardel, F, Giglione, C, Meinnel, T, Ferrer, J.-L. | | Deposit date: | 2005-06-09 | | Release date: | 2005-09-27 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms
J.Biol.Chem., 280, 2005
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1ZY0
 | | X-ray structure of peptide deformylase from Arabidopsis thaliana (AtPDF1A); crystals grown in PEG-6000 | | Descriptor: | Peptide deformylase, mitochondrial, ZINC ION | | Authors: | Fieulaine, S, Juillan-Binard, C, Serero, A, Dardel, F, Giglione, C, Meinnel, T, Ferrer, J.-L. | | Deposit date: | 2005-06-09 | | Release date: | 2005-09-27 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms
J.Biol.Chem., 280, 2005
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2LM7
 | | NMR structure of the C-terminal domain of VP7 in membrane mimicking micelles | | Descriptor: | Outer capsid glycoprotein VP7 | | Authors: | Elaid, S, Libersou, S, Ouldali, M, Morellet, N, Lepault, J, Bouaziz, S. | | Deposit date: | 2011-11-23 | | Release date: | 2012-10-24 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | NMR structure of the C-terminal domain of VP7 in membrane mimicking micelles
To be Published
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