6PW3
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4ZC4
| Crystal structure of LARP1-unique domain DM15 | Descriptor: | La-related protein 1, SULFATE ION | Authors: | Lahr, R.M, Berman, A.J. | Deposit date: | 2015-04-15 | Release date: | 2015-08-05 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequence. Nucleic Acids Res., 43, 2015
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5C0V
| Structure of the LARP1-unique domain DM15 | Descriptor: | La-related protein 1, SULFATE ION | Authors: | Lahr, R.M, Berman, A.J. | Deposit date: | 2015-06-12 | Release date: | 2015-08-05 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequence. Nucleic Acids Res., 43, 2015
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5V87
| Crystal structure of LARP1-unique domain DM15 bound to m7GpppC | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, La-related protein 1, [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-9-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [[(2~{R},3~{S},4~{R},5~{R})-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate | Authors: | Berman, A.J, Lahr, R.M. | Deposit date: | 2017-03-21 | Release date: | 2017-04-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.692 Å) | Cite: | La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs. Elife, 6, 2017
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5V7C
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5V4R
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