1YQE
| Crystal Structure of Conserved Protein of Unknown Function AF0625 | Descriptor: | Hypothetical UPF0204 protein AF0625, PYROPHOSPHATE 2- | Authors: | Liu, Y, Skarina, T, Dong, A, Kudritskam, M, Savchenko, A, Pai, E.F, Edwards, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-02-01 | Release date: | 2005-03-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Crystal Structure of Conserved Hypothetical Protein AF0625 To be Published
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4J0U
| Crystal structure of IFIT5/ISG58 | Descriptor: | Interferon-induced protein with tetratricopeptide repeats 5 | Authors: | Liu, Y, Liang, H, Feng, F, Yuan, L, Wang, Y.E, Crowley, C, Lv, Z, Li, J, Zeng, S, Cheng, G. | Deposit date: | 2013-01-31 | Release date: | 2013-02-13 | Method: | X-RAY DIFFRACTION (1.969 Å) | Cite: | Crystal Structure of IFIT5 To be Published
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7EOE
| Crystal structure of CCDC25 homodimer | Descriptor: | Coiled-coil domain-containing protein 25 | Authors: | Liu, Y.R. | Deposit date: | 2021-04-22 | Release date: | 2022-11-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of CCDC25 homodimer To Be Published
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7U2F
| G116F Pseudomonas aeruginosa azurin | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Azurin, COPPER (II) ION | Authors: | Liu, Y, Lu, Y. | Deposit date: | 2022-02-23 | Release date: | 2023-03-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for the Effects of Phenylalanine on Tuning the Reduction Potential of Type 1 Copper in Azurin. Inorg.Chem., 62, 2023
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2AJH
| Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase complexes with methionine | Descriptor: | Leucyl-tRNA synthetase, METHIONINE | Authors: | Liu, Y, Liao, J, Zhu, B, Wang, E.D, Ding, J. | Deposit date: | 2005-08-02 | Release date: | 2006-01-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination Biochem.J., 394, 2006
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7VJO
| Pectobacterium phage ZF40 apo-Aca2 | Descriptor: | CHLORIDE ION, MAGNESIUM ION, anti-CRISPR-associated protein Aca2 | Authors: | Liu, Y.H, Zhang, L.S, Wu, B.X, Huang, H.D. | Deposit date: | 2021-09-28 | Release date: | 2021-10-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Structural basis for anti-CRISPR repression mediated by bacterial operon proteins Aca1 and Aca2. J.Biol.Chem., 297, 2021
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7VJN
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7VJP
| Selenomethionine-derived Pectobacterium phage ZF40 apo-Aca2 | Descriptor: | SULFATE ION, anti-CRISPR-associated protein Aca2 | Authors: | Liu, Y.H, Zhang, L.S, Wu, B.X, Huang, H.D. | Deposit date: | 2021-09-28 | Release date: | 2021-10-20 | Last modified: | 2022-02-02 | Method: | X-RAY DIFFRACTION (1.594 Å) | Cite: | Structural basis for anti-CRISPR repression mediated by bacterial operon proteins Aca1 and Aca2. J.Biol.Chem., 297, 2021
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6AGS
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3G3D
| Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 5-fluoro-6-azido-UMP | Descriptor: | 5-FLUORO-URIDINE-5'-MONOPHOSPHATE, GLYCEROL, SULFATE ION, ... | Authors: | Liu, Y, Tang, H.L, Bello, A, Poduch, E, Kotra, L, Pai, E. | Deposit date: | 2009-02-02 | Release date: | 2009-03-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents. J.Med.Chem., 52, 2009
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2Q8L
| Crystal structure of orotidine 5'-phosphate decarboxylase from Plasmodium falciparum | Descriptor: | Orotidine-monophosphate-decarboxylase, PHOSPHATE ION | Authors: | Liu, Y, Lau, W, Lew, J, Amani, M, Hui, R, Pai, E.F, Structural Genomics Consortium (SGC) | Deposit date: | 2007-06-11 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of orotidine 5'-phosphate decarboxylase from Plasmodium falciparum. To be Published
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1RGQ
| M9A HCV Protease complex with pentapeptide keto-amide inhibitor | Descriptor: | N-(PYRAZIN-2-YLCARBONYL)LEUCYLISOLEUCYL-N~1~-{1-[2-({1-CARBOXY-2-[4-(PHOSPHONOOXY)PHENYL]ETHYL}AMINO)-1,1-DIHYDROXY-2-OXOETHYL]BUT-3-ENYL}-3-CYCLOHEXYLALANINAMIDE, NS3 Protease, NS4A peptide, ... | Authors: | Liu, Y, Stoll, V.S, Richardson, P.L, Saldivar, A, Klaus, J.L, Molla, A, Kohlbrenner, W, Kati, W.M. | Deposit date: | 2003-11-12 | Release date: | 2004-10-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Hepatitis C NS3 protease inhibition by peptidyl-alpha-ketoamide inhibitors: kinetic mechanism and structure. Arch.Biochem.Biophys., 421, 2004
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2AJI
| Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase complexes with isoleucine | Descriptor: | ISOLEUCINE, Leucyl-tRNA synthetase | Authors: | Liu, Y, Liao, J, Zhu, B, Wang, E.D, Ding, J. | Deposit date: | 2005-08-02 | Release date: | 2006-01-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination Biochem.J., 394, 2006
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3MI2
| Crystal structure of human orotidine-5'-monophosphate decarboxylase complexed with pyrazofurin monophosphate | Descriptor: | (1S)-1,4-anhydro-1-(5-carbamoyl-4-hydroxy-1H-pyrazol-3-yl)-5-O-phosphono-D-ribitol, Uridine 5'-monophosphate synthase | Authors: | Liu, Y, To, T, Kotra, L.P, Pai, E.F. | Deposit date: | 2010-04-09 | Release date: | 2010-05-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural determinants for the inhibitory ligands of orotidine-5'-monophosphate decarboxylase. Bioorg.Med.Chem., 18, 2010
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2AZP
| Crystal Structure of PA1268 Solved by Sulfur SAD | Descriptor: | hypothetical protein PA1268 | Authors: | Liu, Y, Gorodichtchenskaia, E, Skarina, T, Yang, C, Joachimiak, A, Edwards, A, Pai, E.F, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-09-12 | Release date: | 2005-12-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Crystal Structure of PA1268 Solved by Sulfur SAD To be Published
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7KCK
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7KCM
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3MW7
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1YXO
| Crystal Structure of pyridoxal phosphate biosynthetic protein PdxA PA0593 | Descriptor: | 4-hydroxythreonine-4-phosphate dehydrogenase 1, ETHANOL, MAGNESIUM ION | Authors: | Liu, Y, Xu, X, Dong, A, Kudritskam, M, Savchenko, A, Pai, E.F, Joachimiak, A, Edwards, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-02-22 | Release date: | 2005-04-05 | Last modified: | 2011-10-05 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal Structure of pyridoxal phosphate biosynthetic protein PdxA PA0593 To be Published
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5CQ2
| Crystal Structure of tandem WW domains of ITCH in complex with TXNIP peptide | Descriptor: | E3 ubiquitin-protein ligase Itchy homolog, Thioredoxin-interacting protein, UNKNOWN ATOM OR ION | Authors: | Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2015-07-21 | Release date: | 2015-09-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP. Biochem.J., 473, 2016
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3MWA
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2AJG
| Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase | Descriptor: | Leucyl-tRNA synthetase | Authors: | Liu, Y, Liao, J, Zhu, B, Wang, E.D, Ding, J. | Deposit date: | 2005-08-01 | Release date: | 2006-01-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination Biochem.J., 394, 2006
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3N2M
| Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-amino-5-fluorouridine 5'-(dihydrogen phosphate), ... | Authors: | Liu, Y, Kotra, L.P, Pai, E.F. | Deposit date: | 2010-05-18 | Release date: | 2011-04-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP To be Published
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3N34
| Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP, produced from 5-fluoro-6-azido-UMP | Descriptor: | 1,2-ETHANEDIOL, 6-amino-5-fluorouridine 5'-(dihydrogen phosphate), DI(HYDROXYETHYL)ETHER, ... | Authors: | Liu, Y, Kotra, L.P, Pai, E.F. | Deposit date: | 2010-05-19 | Release date: | 2011-04-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP, produced from 5-fluoro-6-azido-UMP To be Published
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3N3M
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