4QDE
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![BU of 4qde by Molmil](/molmil-images/mine/4qde) | Dcps in complex with covalent inhibitor | Descriptor: | 2-{[(2,4-diaminoquinazolin-5-yl)oxy]methyl}benzenesulfonic acid, PHOSPHATE ION, m7GpppX diphosphatase | Authors: | Liu, S. | Deposit date: | 2014-05-13 | Release date: | 2015-05-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Dcps in complex with covalent inhibitors To be Published
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3SIV
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![BU of 3siv by Molmil](/molmil-images/mine/3siv) | Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, dimeric form | Descriptor: | NHP2-like protein 1, U4/U6 small nuclear ribonucleoprotein Prp31, U4atac snRNA | Authors: | Liu, S, Ghalei, H, Luhrmann, R, Wahl, M.C. | Deposit date: | 2011-06-20 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.304 Å) | Cite: | Structural basis for the dual U4 and U4atac snRNA-binding specificity of spliceosomal protein hPrp31. Rna, 17, 2011
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3QBJ
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![BU of 3qbj by Molmil](/molmil-images/mine/3qbj) | Crystal structure of dipeptidyl peptidase IV in complex with inhibitor | Descriptor: | 1-[(3S,4S)-4-amino-1-(6-phenylpyrimidin-4-yl)pyrrolidin-3-yl]piperidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Liu, S.P. | Deposit date: | 2011-01-13 | Release date: | 2012-01-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Crystal structure of dipeptidyl peptidase IV in complex with inhibitor To be Published
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7EKP
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![BU of 7ekp by Molmil](/molmil-images/mine/7ekp) | human alpha 7 nicotinic acetylcholine receptor bound to EVP-6124 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide, ... | Authors: | Liu, S, Zhao, Y, Sun, D, Tian, C. | Deposit date: | 2021-04-06 | Release date: | 2021-05-19 | Last modified: | 2021-06-16 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Structural basis of human alpha 7 nicotinic acetylcholine receptor activation. Cell Res., 31, 2021
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7EKT
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![BU of 7ekt by Molmil](/molmil-images/mine/7ekt) | human alpha 7 nicotinic acetylcholine receptor bound to EVP-6124 and PNU-120596 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide, ... | Authors: | Liu, S, Zhao, Y, Sun, D, Tian, C. | Deposit date: | 2021-04-06 | Release date: | 2021-05-19 | Last modified: | 2021-06-16 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Structural basis of human alpha 7 nicotinic acetylcholine receptor activation. Cell Res., 31, 2021
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6CDY
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![BU of 6cdy by Molmil](/molmil-images/mine/6cdy) | Crystal structure of TEAD complexed with its inhibitor | Descriptor: | 2-[(4H-1,2,4-triazol-3-yl)sulfanyl]-N-{4-[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]decan-1-yl]phenyl}acetamide, Transcriptional enhancer factor TEF-4 | Authors: | LIU, S, HAN, X, LUO, X. | Deposit date: | 2018-02-09 | Release date: | 2020-07-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription. Cell Stem Cell, 26, 2020
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4NV5
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![BU of 4nv5 by Molmil](/molmil-images/mine/4nv5) | C50A mutant of Synechococcus VKOR, C2 crystal form (dehydrated) | Descriptor: | UBIQUINONE-10, VKORC1/thioredoxin domain protein | Authors: | Liu, S, Cheng, W, Fowle Grider, R, Shen, G, Li, W. | Deposit date: | 2013-12-04 | Release date: | 2014-02-12 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer. Nat Commun, 5, 2014
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4NV2
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![BU of 4nv2 by Molmil](/molmil-images/mine/4nv2) | C50A mutant of Synechococcus VKOR, C2221 crystal form | Descriptor: | UBIQUINONE-10, VKORC1/thioredoxin domain protein | Authors: | Liu, S, Cheng, W, Fowle Grider, R, Shen, G, Li, W. | Deposit date: | 2013-12-04 | Release date: | 2014-02-12 | Method: | X-RAY DIFFRACTION (3.61 Å) | Cite: | Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer. Nat Commun, 5, 2014
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4NV6
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![BU of 4nv6 by Molmil](/molmil-images/mine/4nv6) | C212A mutant of Synechococcus VKOR | Descriptor: | UBIQUINONE-10, VKORC1/thioredoxin domain protein | Authors: | Liu, S, Cheng, W, Fowle Grider, R, Shen, G, Li, W. | Deposit date: | 2013-12-04 | Release date: | 2014-02-12 | Method: | X-RAY DIFFRACTION (4.19 Å) | Cite: | Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer. Nat Commun, 5, 2014
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8G89
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![BU of 8g89 by Molmil](/molmil-images/mine/8g89) | HSD17B13 in complex with cofactor and inhibitor | Descriptor: | 3-fluoro-N-({(1r,4r)-4-[(2-fluorophenoxy)methyl]-1-hydroxycyclohexyl}methyl)-4-hydroxybenzamide, Hydroxysteroid 17-beta dehydrogenase 13, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Liu, S. | Deposit date: | 2023-02-17 | Release date: | 2023-08-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.222 Å) | Cite: | Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13. Nat Commun, 14, 2023
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8G84
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![BU of 8g84 by Molmil](/molmil-images/mine/8g84) | Crystal structures of HSD17B13 complexes | Descriptor: | Hydroxysteroid 17-beta dehydrogenase 13, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Liu, S. | Deposit date: | 2023-02-17 | Release date: | 2023-08-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.467 Å) | Cite: | Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13. Nat Commun, 14, 2023
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2MA1
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![BU of 2ma1 by Molmil](/molmil-images/mine/2ma1) | Solution structure of HRDC1 domain of RecQ helicase from Deinococcus radiodurans | Descriptor: | DNA helicase RecQ | Authors: | Liu, S, Zhang, W, Gao, Z, Ming, Q, Hou, H, Lan, W, Wu, H, Cao, C, Dong, Y. | Deposit date: | 2013-06-24 | Release date: | 2013-07-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR structure of the N-terminal-most HRDC1 domain of RecQ helicase from Deinococcus radiodurans To be Published
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7EKI
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![BU of 7eki by Molmil](/molmil-images/mine/7eki) | human alpha 7 nicotinic acetylcholine receptor in apo-form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | Authors: | Liu, S, Zhao, Y, Sun, D, Tian, C. | Deposit date: | 2021-04-05 | Release date: | 2021-05-19 | Last modified: | 2021-06-16 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Structural basis of human alpha 7 nicotinic acetylcholine receptor activation. Cell Res., 31, 2021
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8IVQ
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![BU of 8ivq by Molmil](/molmil-images/mine/8ivq) | Cryo-EM structure of mouse BIRC6, Global map | Descriptor: | Isoform 2 of Baculoviral IAP repeat-containing protein 6 | Authors: | Liu, S, Jiang, T, Bu, F, Zhao, J, Wang, G, Li, N, Gao, N, Qiu, X. | Deposit date: | 2023-03-28 | Release date: | 2024-01-24 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Molecular mechanisms underlying the BIRC6-mediated regulation of apoptosis and autophagy. Nat Commun, 15, 2024
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5W4W
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![BU of 5w4w by Molmil](/molmil-images/mine/5w4w) | |
7WBL
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![BU of 7wbl by Molmil](/molmil-images/mine/7wbl) | Cryo-EM structure of human ACE2 complexed with SARS-CoV-2 Omicron RBD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | Authors: | Liu, S, Gao, F.G. | Deposit date: | 2021-12-17 | Release date: | 2022-01-19 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2. Cell, 185, 2022
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6CPV
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![BU of 6cpv by Molmil](/molmil-images/mine/6cpv) | |
8JEU
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![BU of 8jeu by Molmil](/molmil-images/mine/8jeu) | |
8JET
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![BU of 8jet by Molmil](/molmil-images/mine/8jet) | |
8JEC
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![BU of 8jec by Molmil](/molmil-images/mine/8jec) | |
7X4L
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![BU of 7x4l by Molmil](/molmil-images/mine/7x4l) | Crystal structure of Bacteroides thetaiotaomicron glutamate decarboxylase mutant Y303F-PLP complex | Descriptor: | Glutamate decarboxylase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Liu, S, Guoming, D, Yulu, W, Boting, W, Xin, F. | Deposit date: | 2022-03-02 | Release date: | 2023-05-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple elements under different pH. Food Chem, 403, 2023
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7EJ2
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![BU of 7ej2 by Molmil](/molmil-images/mine/7ej2) | human voltage-gated potassium channel KV1.3 H451N mutant | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium voltage-gated channel subfamily A member 3, Voltage-gated potassium channel subunit beta-2 | Authors: | Liu, S, Zhao, Y, Tian, C. | Deposit date: | 2021-04-01 | Release date: | 2021-06-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of wild-type and H451N mutant human lymphocyte potassium channel K V 1.3. Cell Discov, 7, 2021
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7EJ1
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![BU of 7ej1 by Molmil](/molmil-images/mine/7ej1) | human voltage-gated potassium channel KV1.3 | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium voltage-gated channel subfamily A member 3, Voltage-gated potassium channel subunit beta-2 | Authors: | Liu, S, Zhao, Y, Tian, C. | Deposit date: | 2021-04-01 | Release date: | 2021-06-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of wild-type and H451N mutant human lymphocyte potassium channel K V 1.3. Cell Discov, 7, 2021
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7X4Y
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![BU of 7x4y by Molmil](/molmil-images/mine/7x4y) | Crystal structure of Bacteroides thetaiotaomicron glutamate decarboxylase BTGAD-PLP-GABA complex | Descriptor: | GAMMA-AMINO-BUTANOIC ACID, Glutamate decarboxylase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Liu, S, Du, G, Wang, Y, Wen, B, Xin, F. | Deposit date: | 2022-03-03 | Release date: | 2023-04-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple elements under different pH. Food Chem, 403, 2023
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7X52
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![BU of 7x52 by Molmil](/molmil-images/mine/7x52) | Crystal structure of Bacteroides thetaiotaomicron glutamate decarboxylase BTGAD-PLP complex | Descriptor: | ACETATE ION, Glutamate decarboxylase, MALONATE ION, ... | Authors: | Liu, S, Du, G, Wang, Y, Wen, B, Xin, F. | Deposit date: | 2022-03-03 | Release date: | 2023-04-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple elements under different pH. Food Chem, 403, 2023
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