3N6A
 
 | | Structure of endothelial nitric oxide synthase N368D/V106M double mutant heme domain complexed with 4-(2-(5-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-3-yl)ethyl)-6-methylpyridin-2-amine | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6-(2-{5-[2-(2-amino-6-methylpyridin-4-yl)ethyl]pyridin-3-yl}ethyl)-4-methylpyridin-2-amine, ACETATE ION, ... | | 著者 | Delker, S.L, Li, H, Poulos, T.L. | | 登録日 | 2010-05-25 | | 公開日 | 2011-02-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Role of zinc in isoform-selective inhibitor binding to neuronal nitric oxide synthase .
Biochemistry, 49, 2010
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3N6C
 | | Structure of endothelial nitric oxide synthase H373S single mutant heme domain complexed with 4-(2-(6-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-2-yl)ethyl)-6-methylpyridin-2-amine | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6-(2-{6-[2-(2-amino-6-methylpyridin-4-yl)ethyl]pyridin-2-yl}ethyl)-4-methylpyridin-2-amine, ACETATE ION, ... | | 著者 | Delker, S.L, Li, H, Poulos, T.L. | | 登録日 | 2010-05-25 | | 公開日 | 2011-02-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | | 主引用文献 | Role of zinc in isoform-selective inhibitor binding to neuronal nitric oxide synthase .
Biochemistry, 49, 2010
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3N6F
 | | Structure of endothelial nitric oxide synthase N368D single mutant heme domain complexed with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) | | 分子名称: | 'Nitric oxide synthase, 5,6,7,8-TETRAHYDROBIOPTERIN, 6,6'-(pyridine-3,5-diyldiethane-2,1-diyl)bis(4-methylpyridin-2-amine), ... | | 著者 | Delker, S.L, Li, H, Poulos, T.L. | | 登録日 | 2010-05-25 | | 公開日 | 2011-02-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Role of zinc in isoform-selective inhibitor binding to neuronal nitric oxide synthase .
Biochemistry, 49, 2010
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3HVR
 | | Crystal structure of T. thermophilus Argonaute complexed with DNA guide strand and 19-nt RNA target strand with two Mg2+ at the cleavage site | | 分子名称: | 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*TP*GP*AP*TP*AP*GP*T)-3', 5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', Argonaute, ... | | 著者 | Wang, Y, Li, H, Sheng, G, Patel, D.J. | | 登録日 | 2009-06-16 | | 公開日 | 2009-10-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.211 Å) | | 主引用文献 | Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
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1Q9U
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2NSE
 | | BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE SUBSTRATE COMPLEX | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ARGININE, CACODYLATE ION, ... | | 著者 | Raman, C.S, Li, H, Martasek, P, Kral, V, Masters, B.S.S, Poulos, T.L. | | 登録日 | 1998-08-13 | | 公開日 | 1999-05-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center.
Cell(Cambridge,Mass.), 95, 1998
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2EWC
 | | Structure of hypothetical protein from Streptococcus pyogenes M1 GAS, member of highly conserved yjgF family of proteins | | 分子名称: | GLYCEROL, conserved hypothetical protein | | 著者 | Nocek, B, Li, H, Clancy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-11-02 | | 公開日 | 2005-12-13 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structure of hypothetical protein from Streptococcus pyogenes M1 GAS, member of highly conserved yjgF family of proteins
To be Published
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3RL7
 | | Crystal structure of hDLG1-PDZ1 complexed with APC | | 分子名称: | 11-mer peptide from Adenomatous polyposis coli protein, Disks large homolog 1 | | 著者 | Zhang, Z, Li, H, Wu, G. | | 登録日 | 2011-04-19 | | 公開日 | 2011-12-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular basis for the recognition of adenomatous polyposis coli by the Discs Large 1 protein.
Plos One, 6, 2011
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2OIW
 | | The structure of a predicted thioesterase from Bacillus stearothermophilus | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, putative 4-hydroxybenzoyl-CoA thioesterase | | 著者 | Cuff, M.E, Li, H, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-01-11 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structure of a predicted thioesterase from Bacillus stearothermophilus
TO BE PUBLISHED
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1SS4
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3N5Q
 | | Structure of endothelial nitric oxide synthase heme domain complexed with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6,6'-[(5-aminobenzene-1,3-diyl)diethane-2,1-diyl]bis(4-methylpyridin-2-amine), CACODYLIC ACID, ... | | 著者 | Delker, S.L, Li, H, Poulos, T.L. | | 登録日 | 2010-05-25 | | 公開日 | 2011-02-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Role of zinc in isoform-selective inhibitor binding to neuronal nitric oxide synthase .
Biochemistry, 49, 2010
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3N67
 | | Structure of endothelial nitric oxide synthase N368D/V106M double mutant heme domain complexed with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6,6'-[(5-aminobenzene-1,3-diyl)diethane-2,1-diyl]bis(4-methylpyridin-2-amine), ACETATE ION, ... | | 著者 | Delker, S.L, Li, H, Poulos, T.L. | | 登録日 | 2010-05-25 | | 公開日 | 2011-02-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Role of zinc in isoform-selective inhibitor binding to neuronal nitric oxide synthase .
Biochemistry, 49, 2010
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1U7N
 | | Crystal Structure of the fatty acid/phospholipid synthesis protein PlsX from Enterococcus faecalis V583 | | 分子名称: | 1,2-ETHANEDIOL, ETHANOL, Fatty acid/phospholipid synthesis protein plsX | | 著者 | Kim, Y, Li, H, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2004-08-04 | | 公開日 | 2004-08-17 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Crystal structure of fatty acid/phospholipid synthesis protein PlsX from Enterococcus faecalis.
J.STRUCT.FUNCT.GENOM., 10, 2009
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2JMI
 | | NMR solution structure of PHD finger fragment of Yeast Yng1 protein in free state | | 分子名称: | Protein YNG1, ZINC ION | | 著者 | Ilin, S, Taverna, S.D, Rogers, R.S, Tanny, J.C, Lavender, H, Li, H, Baker, L, Boyle, J, Blair, L.P, Chait, B.T, Patel, D.J, Aitchison, J.D, Tackett, A.J, Allis, C.D. | | 登録日 | 2006-11-15 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs
Mol.Cell, 24, 2006
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3B79
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2P0N
 | | NMB1532 protein from Neisseria meningitidis, unknown function | | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, GLYCEROL, ... | | 著者 | Osipiuk, J, Li, H, Bargassa, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-02-28 | | 公開日 | 2007-03-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | X-ray crystal structure of NMB1532 protein of unknown function from Neisseria meningitidis.
To be Published
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4FYZ
 | | Crystal Structure of Nitrosyl Cytochrome P450cin | | 分子名称: | 1,3,3-TRIMETHYL-2-OXABICYCLO[2.2.2]OCTANE, DI(HYDROXYETHYL)ETHER, NITRIC OXIDE, ... | | 著者 | Madrona, Y, Tripathi, S.M, Li, H, Poulos, T.L. | | 登録日 | 2012-07-05 | | 公開日 | 2012-07-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Crystal structures of substrate-free and nitrosyl cytochrome p450cin: implications for o(2) activation.
Biochemistry, 51, 2012
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5F4Z
 | | The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus | | 分子名称: | (1~{R},2~{R})-2,3-dihydro-1~{H}-indene-1,2-diol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | | 著者 | Tan, K, Li, H, Jedrzejczak, R, BABNIGG, G, BINGMAN, C.A, YENNAMALLI, R, LOHMAN, J, Chang, C.Y, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2015-12-03 | | 公開日 | 2016-02-17 | | 最終更新日 | 2020-09-23 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus
To Be Published
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7VQX
 | | Cryo-EM structure of human vasoactive intestinal polypeptide receptor 2 (VIP2R) in complex with PACAP27 and Gs | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Xu, Y.N, Feng, W.B, Zhou, Q.T, Liang, A.Y, Li, J, Dai, A.T, Zhao, F.H, Yan, J.H, Chen, C.W, Li, H, Zhao, L.H, Xia, T, Jiang, Y, Xu, H.E, Yang, D.H, Wang, M.W. | | 登録日 | 2021-10-21 | | 公開日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | | 主引用文献 | A distinctive ligand recognition mechanism by the human vasoactive intestinal polypeptide receptor 2.
Nat Commun, 13, 2022
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3V5U
 | | Structure of Sodium/Calcium Exchanger from Methanocaldococcus jannaschii DSM 2661 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ACETATE ION, CALCIUM ION, ... | | 著者 | Jiang, Y, Liao, J, Li, H, Zeng, W, Sauer, D, Belmares, R. | | 登録日 | 2011-12-16 | | 公開日 | 2012-02-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural insight into the ion-exchange mechanism of the sodium/calcium exchanger.
Science, 335, 2012
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5TGN
 | | Crystal structure of protein Sthe_2403 from Sphaerobacter thermophilus | | 分子名称: | CHLORIDE ION, GLYCEROL, Uncharacterized protein | | 著者 | Michalska, K, Li, H, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2016-09-28 | | 公開日 | 2016-10-26 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Crystal structure of protein Sthe_2403 from Sphaerobacter thermophilus
To Be Published
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6J2S
 | | Structure of HitA bound to gallium from Pseudomonas aeruginosa | | 分子名称: | Ferric iron-binding periplasmic protein, GALLIUM (III) ION, PHOSPHATE ION | | 著者 | Guo, Y, Li, H.Y, Sun, H.Z, Xia, W. | | 登録日 | 2019-01-02 | | 公開日 | 2020-01-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.73005116 Å) | | 主引用文献 | Identification and Characterization of a Metalloprotein Involved in Gallium Internalization in Pseudomonas aeruginosa.
Acs Infect Dis., 5, 2019
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3LWV
 | | Structure of H/ACA RNP bound to a substrate RNA containing 2'-deoxyuridine | | 分子名称: | 5'-R(*GP*AP*GP*CP*GP*(du)P*GP*CP*GP*GP*UP*UP*U)-3', 50S ribosomal protein L7Ae, H/ACA RNA, ... | | 著者 | Zhou, J, Liang, B, Lv, C, Yang, W, Li, H. | | 登録日 | 2010-02-24 | | 公開日 | 2010-07-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | | 主引用文献 | Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase .
Biochemistry, 49, 2010
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3LWR
 | | Structure of H/ACA RNP bound to a substrate RNA containing 4SU | | 分子名称: | 5'-R(*GP*AP*GP*CP*GP*(4SU)P*GP*CP*GP*GP*UP*UP*U)-3', 50S ribosomal protein L7Ae, H/ACA RNA, ... | | 著者 | Zhou, J, Liang, B, Lv, C, Yang, W, Li, H. | | 登録日 | 2010-02-24 | | 公開日 | 2010-07-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.203 Å) | | 主引用文献 | Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase .
Biochemistry, 49, 2010
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5YF1
 | | Crystal structure of CARNMT1 bound to carnosine and SFG | | 分子名称: | (2~{S})-2-(3-azanylpropanoylamino)-3-(1~{H}-imidazol-4-yl)propanoic acid, 1,2-ETHANEDIOL, ACETATE ION, ... | | 著者 | Cao, R, Li, H. | | 登録日 | 2017-09-20 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.399 Å) | | 主引用文献 | Molecular basis for histidine N1 position-specific methylation by CARNMT1.
Cell Res., 28, 2018
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