5IEU
| Crystal Structure of Mycobacterium Tuberculosis ATP-independent Proteasome Activator Tetramer | 分子名称: | Bacterial proteasome activator | 著者 | Bai, L, Hu, K, Wang, T, Jastrab, J.B, Darwin, K.H, Li, H. | 登録日 | 2016-02-25 | 公開日 | 2016-03-30 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural analysis of the dodecameric proteasome activator PafE in Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 113, 2016
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5UR9
| Enantiomer-Specific Binding of the Potent Antinociceptive Agent SBFI-26 to Anandamide transporters FABP5 | 分子名称: | (1S,2S,3S,4S)-3-{[(naphthalen-1-yl)oxy]carbonyl}-2,4-diphenylcyclobutane-1-carboxylic acid, Fatty acid-binding protein, epidermal, ... | 著者 | Hsu, H.-C, Li, H. | 登録日 | 2017-02-09 | 公開日 | 2017-08-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.19800353 Å) | 主引用文献 | The Antinociceptive Agent SBFI-26 Binds to Anandamide Transporters FABP5 and FABP7 at Two Different Sites. Biochemistry, 56, 2017
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1BVY
| COMPLEX OF THE HEME AND FMN-BINDING DOMAINS OF THE CYTOCHROME P450(BM-3) | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, PROTEIN (CYTOCHROME P450 BM-3), ... | 著者 | Sevrioukova, I.F, Li, H, Zhang, H, Peterson, J.A, Poulos, T.L. | 登録日 | 1998-09-21 | 公開日 | 1999-02-23 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structure of a cytochrome P450-redox partner electron-transfer complex. Proc.Natl.Acad.Sci.USA, 96, 1999
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1Q5E
| Substrate-free Cytochrome P450epoK | 分子名称: | P450 epoxidase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Nagano, S, Li, H, Shimizu, H, Nishida, C, Ogura, H, Ortiz de Montellano, P.R, Poulos, T.L. | 登録日 | 2003-08-06 | 公開日 | 2003-10-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Crystal structures of epothilone D-bound, epothilone B-bound, and substrate-free forms of cytochrome P450epoK J.Biol.Chem., 278, 2003
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7KY7
| Structure of the S. cerevisiae phosphatidylcholine flippase Dnf2-Lem3 complex in the apo E1 state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alkylphosphocholine resistance protein LEM3, CHOLESTEROL, ... | 著者 | Bai, L, You, Q, Jain, B.K, Duan, H.D, Kovach, A, Graham, T.R, Li, H. | 登録日 | 2020-12-07 | 公開日 | 2021-01-06 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Transport mechanism of P4 ATPase phosphatidylcholine flippases. Elife, 9, 2020
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7KY6
| Structure of the S. cerevisiae phosphatidylcholine flippase Dnf1-Lem3 complex in the apo E1 state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alkylphosphocholine resistance protein LEM3, ... | 著者 | Bai, L, You, Q, Jain, B.K, Duan, H.D, Kovach, A, Graham, T.R, Li, H. | 登録日 | 2020-12-07 | 公開日 | 2021-01-06 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Transport mechanism of P4 ATPase phosphatidylcholine flippases. Elife, 9, 2020
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7KYA
| Structure of the S. cerevisiae phosphatidylcholine flippase Dnf2-Lem3 complex in the E2P state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alkylphosphocholine resistance protein LEM3, ... | 著者 | Bai, L, You, Q, Jain, B.K, Duan, H.D, Kovach, A, Graham, T.R, Li, H. | 登録日 | 2020-12-07 | 公開日 | 2021-01-06 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Transport mechanism of P4 ATPase phosphatidylcholine flippases. Elife, 9, 2020
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4ZMG
| Crystal structure of Human Dihydroorotate Dehydrogenase (DHODH) with DH03A338 | 分子名称: | 1-(3,5-difluoro-3'-methoxybiphenyl-4-yl)-3-(1,3-thiazol-5-yl)urea, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | 著者 | Ren, X.L, Zhu, J.S, Zhu, L.L, Li, H.L. | 登録日 | 2015-05-04 | 公開日 | 2016-05-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of Human Dihydroorotate Dehydrogenase (DHODH) with DH03A338 To Be Published
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6DJV
| Mtb ClpB in complex with ATPgammaS and casein, Conformer 2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Yu, H.J, Li, H.L. | 登録日 | 2018-05-26 | 公開日 | 2018-09-26 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | ATP hydrolysis-coupled peptide translocation mechanism ofMycobacterium tuberculosisClpB. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6DJU
| Mtb ClpB in complex with ATPgammaS and casein, Conformer 1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Yu, H.J, Li, H.L. | 登録日 | 2018-05-26 | 公開日 | 2018-09-26 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | ATP hydrolysis-coupled peptide translocation mechanism ofMycobacterium tuberculosisClpB. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1PKF
| Crystal Structure of Epothilone D-bound Cytochrome P450epoK | 分子名称: | EPOTHILONE D, PROTOPORPHYRIN IX CONTAINING FE, cytochrome p450EpoK | 著者 | Nagano, S, Li, H, Shimizu, H, Nishida, C, Ogura, H, Ortiz de Montellano, P.R, Poulos, T.L. | 登録日 | 2003-06-05 | 公開日 | 2003-10-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structures of Epothilone D-bound, Epothilone B-bound, and Substrate-free Forms of Cytochrome P450epoK J.Biol.Chem., 278, 2003
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5VVO
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2PDO
| Crystal Structure of the Putative Acetyltransferase of GNAT Family from Shigella flexneri | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, Acetyltransferase ypeA, ... | 著者 | Kim, Y, Li, H, Holzle, D, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2007-04-01 | 公開日 | 2007-04-24 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of the Putative Acetyltransferase of GNAT Family from Shigella flexneri To be Published
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1AP8
| TRANSLATION INITIATION FACTOR EIF4E IN COMPLEX WITH M7GDP, NMR, 20 STRUCTURES | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, TRANSLATION INITIATION FACTOR EIF4E | 著者 | Matsuo, H, Li, H, Mcguire, A.M, Fletcher, M, Gingras, A.C, Sonenberg, N, Wagner, G. | 登録日 | 1997-07-25 | 公開日 | 1998-01-28 | 最終更新日 | 2024-03-06 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein. Nat.Struct.Biol., 4, 1997
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2RE1
| Crystal structure of aspartokinase alpha and beta subunits | 分子名称: | Aspartokinase, alpha and beta subunits, CALCIUM ION | 著者 | Chang, C, Li, H, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2007-09-25 | 公開日 | 2007-10-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal structure of aspartokinase alpha and beta subunits. To be Published
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3HJW
| Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA | 分子名称: | 5'-R(*GP*AP*GP*CP*GP*(FHU)P*GP*CP*GP*GP*UP*UP*U)-3', 50S ribosomal protein L7Ae, POTASSIUM ION, ... | 著者 | Liang, B, Zhou, J, Kahen, E, Terns, R.M, Terns, M.P, Li, H. | 登録日 | 2009-05-22 | 公開日 | 2009-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA Nat.Struct.Mol.Biol., 16, 2009
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2RK5
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1PKH
| STRUCTURAL BASIS FOR RECOGNITION AND CATALYSIS BY THE BIFUNCTIONAL DCTP DEAMINASE AND DUTPASE FROM METHANOCOCCUS JANNASCHII | 分子名称: | 1,2-ETHANEDIOL, Bifunctional deaminase/diphosphatase | 著者 | Huffman, J.L, Li, H, White, R.H, Tainer, J.A. | 登録日 | 2003-06-05 | 公開日 | 2003-08-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii J.Mol.Biol., 331, 2003
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6WB9
| Structure of the S. cerevisiae ER membrane complex | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ER membrane protein complex subunit 1, ... | 著者 | Bai, L, Li, H. | 登録日 | 2020-03-26 | 公開日 | 2020-06-03 | 最終更新日 | 2020-09-02 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of the ER membrane complex, a transmembrane-domain insertase. Nature, 584, 2020
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5AL9
| Structure of Leishmania major peroxidase D211R mutant (high res) | 分子名称: | ASCORBATE PEROXIDASE, CALCIUM ION, POTASSIUM ION, ... | 著者 | Chreifi, G, Hollingsworth, S.A, Li, H, Tripathi, S, Arce, A.P, Magana-Garcia, H.I, Poulos, T.L. | 登録日 | 2015-03-07 | 公開日 | 2015-05-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Enzymatic Mechanism of Leishmania major Peroxidase and the Critical Role of Specific Ionic Interactions. Biochemistry, 54, 2015
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7L6N
| The Mycobacterium tuberculosis ClpB disaggregase hexamer structure with three locally refined ClpB middle domains and three DnaK nucleotide binding domains | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, Chaperone protein DnaK, ... | 著者 | Yin, Y.Y, Feng, X, Li, H. | 登録日 | 2020-12-23 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system. Cell Rep, 35, 2021
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3JWS
| Structure of neuronal nitric oxide synthase R349A mutant heme domain complexed with N1-[(3' S,4'S)-4'-((6"-amino-4"-methylpyridin-2"-yl)methyl)pyrrolidin-3'-yl]-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-{(3S,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-[2-(3-fluorophenyl)ethyl]ethane-1,2-diamine, ... | 著者 | Delker, S.L, Li, H, Poulos, T.L. | 登録日 | 2009-09-18 | 公開日 | 2010-05-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model. J.Am.Chem.Soc., 132, 2010
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3JX2
| Structure of rat neuronal nitric oxide synthase D597N/M336V mutant heme domain in complex with N1-{(3'S,4'S)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, GLYCEROL, ... | 著者 | Delker, S.L, Li, H, Poulos, T.L. | 登録日 | 2009-09-18 | 公開日 | 2010-05-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model. J.Am.Chem.Soc., 132, 2010
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3JWZ
| Structure of endothelial nitric oxide synthase heme domain complexed with N1-[(3' S,4' R)-4'-((6"-amino-4"-methylpyridin-2"-yl)methyl)pyrrolidin-3'-yl]-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLIC ACID, ... | 著者 | Delker, S.L, Li, H, Poulos, T.L. | 登録日 | 2009-09-18 | 公開日 | 2010-05-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model. J.Am.Chem.Soc., 132, 2010
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2QHK
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