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PDB: 1782 件
6PTN
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BU of 6ptn by Molmil
Structure of Ctf4 trimer in complex with two CMG helicases
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA polymerase alpha-binding protein, ...
著者Yuan, Z, Georgescu, R, Bai, L, Santos, R, Donnell, M, Li, H.
登録日2019-07-16
公開日2019-11-20
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Ctf4 organizes sister replisomes and Pol alpha into a replication factory.
Elife, 8, 2019
3ERC
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BU of 3erc by Molmil
Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase with three fragments of RNA and 3'-deoxy ATP
分子名称: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, ...
著者Li, C, Li, H, Zhou, S, Poulos, T.L, Gershon, P.D.
登録日2008-10-01
公開日2009-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase
Structure, 17, 2009
4QBR
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BU of 4qbr by Molmil
Crystal structure of DNMT3a ADD domain G550D mutant bound to H3 peptide
分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone H3, ZINC ION
著者Wang, H, Li, H.
登録日2014-05-08
公開日2015-05-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs
To be Published
6OCZ
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BU of 6ocz by Molmil
Crystal Structure of Mycobacterium tuberculosis Proteasome in Complex with Phenylimidazole-based Inhibitor A86
分子名称: CITRIC ACID, DIMETHYLFORMAMIDE, N-{(2S)-1-({(2S)-1-[(2,4-difluorobenzyl)amino]-1-oxopropan-2-yl}amino)-1,4-dioxo-4-[(2R)-2-phenylpyrrolidin-1-yl]butan-2-yl}-5-methyl-1,2-oxazole-3-carboxamide (non-preferred name), ...
著者Hsu, H.C, Li, H.
登録日2019-03-25
公開日2019-10-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Selective Phenylimidazole-Based Inhibitors of theMycobacterium tuberculosisProteasome.
J.Med.Chem., 62, 2019
8UNJ
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BU of 8unj by Molmil
Atomic model of the human CTF18-RFC alone in the apo state (State 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, MAGNESIUM ION, ...
著者Wang, F, He, Q, Li, H.
登録日2023-10-19
公開日2024-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
Proc.Natl.Acad.Sci.USA, 121, 2024
8UI8
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BU of 8ui8 by Molmil
Cryo-EM map of human clamp-clamp loader ATAD5-RFC-two PCNAs complex in intermediate state 3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATPase family AAA domain-containing protein 5, MAGNESIUM ION, ...
著者Wang, F, He, Q, Li, H.
登録日2023-10-10
公開日2024-05-29
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader.
Nat.Struct.Mol.Biol., 2024
1Z29
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BU of 1z29 by Molmil
Crystal Structures of SULT1A2 and SULT1A1*3: Implications in the bioactivation of N-hydroxy-2-acetylamino fluorine (OH-AAF)
分子名称: ACETIC ACID, ADENOSINE-3'-5'-DIPHOSPHATE, CALCIUM ION, ...
著者Lu, J, Li, H, Liu, M.C, Zhang, J, Li, M, An, X, Chang, W.
登録日2005-03-07
公開日2006-05-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of SULT1A2 and SULT1A1 *3: insights into the substrate inhibition and the role of Tyr149 in SULT1A2.
Biochem.Biophys.Res.Commun., 396, 2010
4R05
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BU of 4r05 by Molmil
Crystal structure of the refolded DENV3 methyltransferase
分子名称: Nonstructural protein NS5
著者Brecher, M.B, Li, Z, Zhang, J, Chen, H, Lin, Q, Liu, B, Li, H.M.
登録日2014-07-29
公開日2014-11-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase.
Protein Sci., 24, 2015
4MO7
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BU of 4mo7 by Molmil
Crystal structure of superantigen PfiT
分子名称: BETA-MERCAPTOETHANOL, MAGNESIUM ION, Transcriptional regulator I2
著者Liu, L.H, Chen, H, Li, H.M.
登録日2013-09-11
公開日2014-02-05
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Pfit is a structurally novel Crohn's disease-associated superantigen.
Plos Pathog., 9, 2013
5VIF
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BU of 5vif by Molmil
Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase
分子名称: 2-{[(2E)-4-chlorobut-2-enoyl]amino}-2-deoxy-beta-D-glucopyranose, CKII, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ...
著者Jiang, J, Li, B, Hu, C.-W, Worth, M, Fan, D, Li, H.
登録日2017-04-15
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase.
Nat. Chem. Biol., 13, 2017
2AFF
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BU of 2aff by Molmil
The solution structure of the Ki67FHA/hNIFK(226-269)3P complex
分子名称: Antigen KI-67, MKI67 FHA domain interacting nucleolar phosphoprotein
著者Byeon, I.-J.L, Li, H, Song, H, Gronenborn, A.M, Tsai, M.D.
登録日2005-07-25
公開日2005-10-25
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Sequential phosphorylation and multisite interactions characterize specific target recognition by the FHA domain of Ki67.
Nat.Struct.Mol.Biol., 12, 2005
4IQ2
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BU of 4iq2 by Molmil
P21 crystal form of FKBP12.6
分子名称: MALONIC ACID, Peptidyl-prolyl cis-trans isomerase FKBP1B
著者Chen, H, Mustafi, S.M, Li, H.M, LeMaster, D.M, Hernandez, G.
登録日2013-01-10
公開日2014-01-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6.
Acta Crystallogr.,Sect.D, 70, 2014
4IQC
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BU of 4iqc by Molmil
P3121 crystal form of FKBP12.6
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B
著者Chen, H, Mustafi, S.M, Li, H.M, LeMaster, D.M, Hernandez, G.
登録日2013-01-11
公開日2014-01-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6.
Acta Crystallogr.,Sect.D, 70, 2014
4MXM
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BU of 4mxm by Molmil
Crystal structure of superantigen pfit
分子名称: Transcriptional regulator I2
著者Liu, L.H, Chen, H, Li, H.M.
登録日2013-09-26
公開日2014-09-17
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Pfit is a structurally novel Crohn's disease-associated superantigen.
Plos Pathog., 9, 2013
3ER9
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BU of 3er9 by Molmil
Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase complex with UU and 3'-deoxy ATP
分子名称: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-R(UP*U)-3', CALCIUM ION, ...
著者Li, C, Li, H, Zhou, S, Poulos, T.L, Gershon, P.D.
登録日2008-10-01
公開日2009-06-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase
Structure, 17, 2009
9BCZ
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BU of 9bcz by Molmil
Chicken 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (PLCZ1) in complex with calcium and phosphorylated threonine
分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
著者Edwards, M.M, Dong, A, Theo-Emegano, N, Seitova, A, Loppnau, P, Leung, R, Li, H, Ilyassov, O, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
登録日2024-04-10
公開日2024-05-15
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Chicken 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (PLCZ1) in complex with calcium and phosphorylated threonine
To be published
2YTM
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BU of 2ytm by Molmil
Solution structure of the C2H2 type zinc finger (region 696-728) of human Zinc finger protein 28 homolog
分子名称: ZINC ION, Zinc finger protein 28 homolog
著者Tochio, N, Tomizawa, T, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-05
公開日2007-10-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the C2H2 type zinc finger (region 696-728) of human Zinc finger protein 28 homolog
To be Published
2YTE
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BU of 2yte by Molmil
Solution structure of the C2H2 type zinc finger (region 484-512) of human Zinc finger protein 473
分子名称: ZINC ION, Zinc finger protein 473
著者Tomizawa, T, Tochio, N, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-05
公開日2007-10-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the C2H2 type zinc finger (region 484-512) of human Zinc finger protein 473
To be Published
2YTN
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BU of 2ytn by Molmil
Solution structure of the C2H2 type zinc finger (region 732-764) of human Zinc finger protein 347
分子名称: ZINC ION, Zinc finger protein 347
著者Tochio, N, Tomizawa, T, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-05
公開日2007-10-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the C2H2 type zinc finger (region 732-764) of human Zinc finger protein 347
To be Published
3OWG
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BU of 3owg by Molmil
Crystal structure of vaccinia virus Polyadenylate polymerase(vp55)
分子名称: Poly(A) polymerase catalytic subunit
著者Li, C, Li, H, Zhou, S, Gershon, P.D, Poulos, T.L.
登録日2010-09-17
公開日2011-09-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Domain-level rocking motion within a polymerase that translocates on single-stranded nucleic acid.
Acta Crystallogr.,Sect.D, 69, 2013
2YTJ
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BU of 2ytj by Molmil
Solution structure of the C2H2 type zinc finger (region 771-803) of human Zinc finger protein 484
分子名称: ZINC ION, Zinc finger protein 484
著者Tomizawa, T, Tochio, N, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-05
公開日2007-10-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the C2H2 type zinc finger (region 771-803) of human Zinc finger protein 484
To be Published
1B9E
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BU of 1b9e by Molmil
HUMAN INSULIN MUTANT SERB9GLU
分子名称: PROTEIN (INSULIN)
著者Wang, D.C, Zeng, Z.H, Yao, Z.P, Li, H.M.
登録日1998-11-12
公開日1999-11-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of an insulin dimer in an orthorhombic crystal: the structure analysis of a human insulin mutant (B9 Ser-->Glu).
Acta Crystallogr.,Sect.D, 55, 1999
2QMW
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BU of 2qmw by Molmil
The crystal structure of the prephenate dehydratase (PDT) from Staphylococcus aureus subsp. aureus Mu50
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Tan, K, Zhang, R, Li, H, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2007-07-17
公開日2007-08-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of open (R) and close (T) states of prephenate dehydratase (PDT) - implication of allosteric regulation by L-phenylalanine.
J.Struct.Biol., 162, 2008
2YTD
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BU of 2ytd by Molmil
Solution structure of the C2H2 type zinc finger (region 426-458) of human Zinc finger protein 473
分子名称: ZINC ION, Zinc finger protein 473
著者Tomizawa, T, Tochio, N, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-05
公開日2007-10-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the C2H2 type zinc finger (region 426-458) of human Zinc finger protein 473
To be Published
2YTK
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BU of 2ytk by Molmil
Solution structure of the C2H2 type zinc finger (region 396-428) of human Zinc finger protein 347
分子名称: ZINC ION, Zinc finger protein 347
著者Tomizawa, T, Tochio, N, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-05
公開日2007-10-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the C2H2 type zinc finger (region 396-428) of human Zinc finger protein 347
To be Published

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