6W6H
 
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6W6J
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6W6I
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7TFI
 | | Atomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with an open clamp | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | | 登録日 | 2022-01-06 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022
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7TFH
 | | Atomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to two DNA molecules, one at the 5'-recessed end and the other at the 3'-recessed end | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | | 登録日 | 2022-01-06 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022
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7TFJ
 | | Atomic model of S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with a closed clamp ring | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | | 登録日 | 2022-01-06 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022
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6PTN
 | | Structure of Ctf4 trimer in complex with two CMG helicases | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA polymerase alpha-binding protein, ... | | 著者 | Yuan, Z, Georgescu, R, Bai, L, Santos, R, Donnell, M, Li, H. | | 登録日 | 2019-07-16 | | 公開日 | 2019-11-20 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | | 主引用文献 | Ctf4 organizes sister replisomes and Pol alpha into a replication factory.
Elife, 8, 2019
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3B3O
 | | Structure of neuronal nos heme domain in complex with a inhibitor (+-)-n1-{cis-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-n2-(4'-chlorobenzyl)ethane-1,2-diamine | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE, ... | | 著者 | Igarashi, J, Li, H, Poulos, T.L. | | 登録日 | 2007-10-22 | | 公開日 | 2008-11-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structures of constitutive nitric oxide synthases in complex with de novo designed inhibitors.
J.Med.Chem., 52, 2009
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1NDG
 | | Crystal structure of Fab fragment of antibody HyHEL-8 complexed with its antigen lysozyme | | 分子名称: | ACETIC ACID, Lysozyme C, antibody kappa light chain, ... | | 著者 | Mariuzza, R.A, Li, Y, Li, H, Yang, F, Smith-Gill, S.J. | | 登録日 | 2002-12-09 | | 公開日 | 2003-06-03 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray snapshots of the maturation of an antibody response to a protein antigen
Nat.Struct.Biol., 10, 2003
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3KPH
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1DM6
 | | BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH N-(4-CHLOROPHENYL)-N'-HYDROXYGUANIDINE (H4B FREE) | | 分子名称: | ACETATE ION, CACODYLATE ION, N-(CHLOROPHENYL)-N'-HYDROXYGUANIDINE, ... | | 著者 | Raman, C.S, Li, H, Martasek, P, Southan, G.J, Masters, B.S.S, Poulos, T.L. | | 登録日 | 1999-12-13 | | 公開日 | 2000-12-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism.
Biochemistry, 40, 2001
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1D0O
 | | BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 3-BROMO-7-NITROINDAZOLE (H4B PRESENT) | | 分子名称: | 3-BROMO-7-NITROINDAZOLE, ACETATE ION, BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME, ... | | 著者 | Raman, C.S, Li, H, Martasek, P, Southan, G.J, Masters, B.S.S, Poulos, T.L. | | 登録日 | 1999-09-13 | | 公開日 | 2001-11-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism.
Biochemistry, 40, 2001
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1B9E
 | | HUMAN INSULIN MUTANT SERB9GLU | | 分子名称: | PROTEIN (INSULIN) | | 著者 | Wang, D.C, Zeng, Z.H, Yao, Z.P, Li, H.M. | | 登録日 | 1998-11-12 | | 公開日 | 1999-11-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of an insulin dimer in an orthorhombic crystal: the structure analysis of a human insulin mutant (B9 Ser-->Glu).
Acta Crystallogr.,Sect.D, 55, 1999
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3KRD
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1DM7
 | | BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH HOMOARGININE (H4B FREE) | | 分子名称: | ACETATE ION, CACODYLATE ION, GLYCEROL, ... | | 著者 | Raman, C.S, Li, H, Martasek, P, Southan, G.J, Masters, B.S.S, Poulos, T.L. | | 登録日 | 1999-12-13 | | 公開日 | 2000-12-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structures of Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed With Various Inhibitors
To be Published
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1DM8
 | | BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 1,2,4-TRIAZOLE-CARBOXAMIDINE (H4B BOUND) | | 分子名称: | 1,2,4-TRIAZOLE-CARBOXAMIDINE, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... | | 著者 | Raman, C.S, Li, H, Martasek, P, Southan, G.J, Masters, B.S.S, Poulos, T.L. | | 登録日 | 1999-12-13 | | 公開日 | 2000-12-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal Structures of Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed With Various Inhibitors
To be Published
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1P3T
 | | Crystal Structures of the NO-and CO-Bound Heme Oxygenase From Neisseria Meningitidis: Implications for Oxygen Activation | | 分子名称: | Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Friedman, J, Lad, L, Deshmukh, R, Li, H, Wilks, A, Poulos, T.L. | | 登録日 | 2003-04-18 | | 公開日 | 2003-12-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of the NO- and CO-bound heme oxygenase from Neisseriae meningitidis. Implications for O2 activation
J.Biol.Chem., 278, 2003
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1P3V
 | | Crystal Structures of the NO-and CO-Bound Heme Oxygenase From Neisseria Meningitidis: Implications for Oxygen Activation | | 分子名称: | CARBON MONOXIDE, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Friedman, J, Lad, L, Deshmukh, R, Li, H, Wilks, A, Poulos, T.L. | | 登録日 | 2003-04-18 | | 公開日 | 2003-12-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal structures of the NO- and CO-bound heme oxygenase from Neisseriae meningitidis. Implications for O2 activation
J.Biol.Chem., 278, 2003
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8D4X
 | | Structure of the human UBR5 HECT-type E3 ubiquitin ligase in a dimeric form | | 分子名称: | E3 ubiquitin-protein ligase UBR5, ZINC ION | | 著者 | Wang, F, He, Q, Lin, G, Li, H. | | 登録日 | 2022-06-02 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structure of the human UBR5 E3 ubiquitin ligase.
Structure, 31, 2023
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2RK5
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2J3E
 | | Dimerization is important for the GTPase activity of chloroplast translocon components atToc33 and psToc159 | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, T7I23.11 PROTEIN | | 著者 | Yeh, Y.-H, Kesavulu, M.M, Wu, S.-Z, Li, H.-M, Sun, Y.-J, Konozy, E.H, Hsiao, C.-D. | | 登録日 | 2006-08-21 | | 公開日 | 2007-03-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Dimerization is Important for the Gtpase Activity of Chloroplast Translocon Components Attoc33 and Pstoc159.
J.Biol.Chem., 282, 2007
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1Y9K
 | | IAA acetyltransferase from Bacillus cereus ATCC 14579 | | 分子名称: | IAA acetyltransferase | | 著者 | Nocek, B.P, Osipiuk, J, Li, H, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2004-12-15 | | 公開日 | 2005-02-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | A crystal structure of IAA acetyltransferase from Bacillus cereus
To be Published
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3OWG
 | | Crystal structure of vaccinia virus Polyadenylate polymerase(vp55) | | 分子名称: | Poly(A) polymerase catalytic subunit | | 著者 | Li, C, Li, H, Zhou, S, Gershon, P.D, Poulos, T.L. | | 登録日 | 2010-09-17 | | 公開日 | 2011-09-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Domain-level rocking motion within a polymerase that translocates on single-stranded nucleic acid.
Acta Crystallogr.,Sect.D, 69, 2013
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1Y1O
 | | X-ray crystal Structure of Penicillin-binding protein-related factor A from Bacillus stearothermophilus | | 分子名称: | NICKEL (II) ION, Penicillin-binding protein-related factor A, SULFATE ION | | 著者 | Osipiuk, J, Li, H, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2004-11-19 | | 公開日 | 2004-12-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | X-ray crystal Structure of Penicillin-binding protein-related factor A from Bacillus stearothermophilus
To be Published
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1TVK
 | | The binding mode of epothilone A on a,b-tubulin by electron crystallography | | 分子名称: | EPOTHILONE A, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Nettles, J.H, Li, H, Cornett, B, Krahn, J.M, Snyder, J.P, Downing, K.H. | | 登録日 | 2004-06-29 | | 公開日 | 2004-09-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.89 Å) | | 主引用文献 | The binding mode of epothilone A on alpha,beta-tubulin by electron crystallography
Science, 305, 2004
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