1VGN
| Structure-based design of the irreversible inhibitors to metallo--lactamase (IMP-1) | 分子名称: | 3-OXO-3-[(3-OXOPROPYL)SULFANYL]PROPANE-1-THIOLATE, ACETIC ACID, Beta-lactamase IMP-1, ... | 著者 | Kurosaki, H, Yamaguchi, Y, Higashi, T, Soga, K, Matsueda, S, Misumi, S, Yamagata, Y, Arakawa, Y, Goto, M. | 登録日 | 2004-04-27 | 公開日 | 2005-06-21 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Irreversible Inhibition of Metallo-beta-lactamase (IMP-1) by 3-(3-Mercaptopropionylsulfanyl)propionic Acid Pentafluorophenyl Ester Angew.Chem.Int.Ed.Engl., 44, 2005
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2DOO
| The structure of IMP-1 complexed with the detecting reagent (DansylC4SH) by a fluorescent probe | 分子名称: | BETA-LACTAMASE IMP-1, N-[4-({[5-(DIMETHYLAMINO)-1-NAPHTHYL]SULFONYL}AMINO)BUTYL]-3-SULFANYLPROPANAMIDE, ZINC ION | 著者 | Kurosaki, H, Yamaguchi, Y, Yasuzawa, H, Jin, W, Yamagata, Y, Arakawa, Y. | 登録日 | 2006-05-01 | 公開日 | 2006-11-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Probing, inhibition, and crystallographic characterization of metallo-beta-lactamase (IMP-1) with fluorescent agents containing dansyl and thiol groups Chemmedchem, 1, 2006
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7WZU
| Crystal structure of metallo-beta-lactamase IMP-6. | 分子名称: | Beta-lactamase, ZINC ION | 著者 | Yamaguchi, Y, Kurosaki, H. | 登録日 | 2022-02-19 | 公開日 | 2023-01-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.954 Å) | 主引用文献 | Difference in the Inhibitory Effect of Thiol Compounds and Demetallation Rates from the Zn(II) Active Site of Metallo-beta-lactamases (IMP-1 and IMP-6) Associated with a Single Amino Acid Substitution. Acs Infect Dis., 9, 2023
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4UBQ
| Crystal Structure of IMP-2 Metallo-beta-Lactamase from Acinetobacter spp. | 分子名称: | ACETATE ION, Beta-lactamase, ZINC ION | 著者 | Yamaguchi, Y, Matsueda, S, Matsunaga, K, Takashio, N, Toma-Fukai, S, Yamagata, Y, Shibata, N, Wachino, J, Shibayama, K, Arakawa, Y, Kurosaki, H. | 登録日 | 2014-08-13 | 公開日 | 2014-12-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of IMP-2 metallo-beta-lactamase from Acinetobacter spp.: comparison of active-site loop structures between IMP-1 and IMP-2. Biol.Pharm.Bull., 38, 2015
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3L6N
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2YZ3
| Crystallographic Investigation of Inhibition Mode of the VIM-2 Metallo-beta-lactamase from Pseudomonas aeruginosa with Mercaptocarboxylate Inhibitor | 分子名称: | (S)-2-(MERCAPTOMETHYL)-5-PHENYLPENTANOIC ACID, Metallo-beta-lactamase, SULFATE ION, ... | 著者 | Yamaguchi, Y, Yamagata, Y, Arakawa, Y, Kurosaki, H. | 登録日 | 2007-05-02 | 公開日 | 2008-03-11 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystallographic investigation of the inhibition mode of a VIM-2 metallo-beta-lactamase from Pseudomonas aeruginosa by a mercaptocarboxylate inhibitor. J.Med.Chem., 50, 2007
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2ZJ9
| X-ray crystal structure of AmpC beta-Lactamase (AmpC(D)) from an Escherichia coli with a Tripeptide Deletion (Gly286 Ser287 Asp288) on the H10 Helix | 分子名称: | AmpC, ISOPROPYL ALCOHOL, SODIUM ION | 著者 | Yamaguchi, Y, Sato, G, Yamagata, Y, Wachino, J, Arakawa, Y, Kurosaki, H. | 登録日 | 2008-02-29 | 公開日 | 2009-03-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of AmpC beta-lactamase (AmpCD) from an Escherichia coli clinical isolate with a tripeptide deletion (Gly286-Ser287-Asp288) in the H10 helix Acta Crystallogr.,Sect.F, 65, 2009
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7DTM
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7DTN
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