2ZKH
 
 | | Human thrombopoietin neutralizing antibody TN1 FAB | | 分子名称: | Monoclonal TN1 FAB heavy chain, Monoclonal TN1 FAB light chain | | 著者 | Arai, S, Tamada, T, Honjo, E, Maeda, Y, Kuroki, R. | | 登録日 | 2008-03-21 | | 公開日 | 2009-03-24 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | An insight into the thermodynamic characteristics of human thrombopoietin complexation with TN1 antibody.
Protein Sci., 25, 2016
|
|
2ZIK
 | |
2ZIJ
 | |
2ZIL
 | |
2E0M
 | | Mutant Human Ribonuclease 1 (T24L, Q28L, R31L, R32L) | | 分子名称: | CADMIUM ION, CHLORIDE ION, Ribonuclease | | 著者 | Yamada, H, Tamada, T, Kosaka, M, Kuroki, R. | | 登録日 | 2006-10-10 | | 公開日 | 2007-08-28 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | 'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines
Protein Sci., 16, 2007
|
|
2E0O
 | | Mutant Human Ribonuclease 1 (V52L, D53L, N56L, F59L) | | 分子名称: | GLYCEROL, Ribonuclease, SULFATE ION | | 著者 | Yamada, H, Tamada, T, Kosaka, M, Kuroki, R. | | 登録日 | 2006-10-10 | | 公開日 | 2007-08-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | 'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines
Protein Sci., 16, 2007
|
|
2E0L
 | | Mutant Human Ribonuclease 1 (Q28L, R31L, R32L) | | 分子名称: | CADMIUM ION, CHLORIDE ION, Ribonuclease | | 著者 | Yamada, H, Tamada, T, Kosaka, M, Kuroki, R. | | 登録日 | 2006-10-10 | | 公開日 | 2007-08-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | 'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines
Protein Sci., 16, 2007
|
|
2E0J
 | | Mutant Human Ribonuclease 1 (R31L, R32L) | | 分子名称: | Ribonuclease | | 著者 | Yamada, H, Tamada, T, Kosaka, M, Kuroki, R. | | 登録日 | 2006-10-10 | | 公開日 | 2007-08-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | 'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines
Protein Sci., 16, 2007
|
|
2ZYE
 | | Structure of HIV-1 Protease in Complex with Potent Inhibitor KNI-272 Determined by Neutron Crystallography | | 分子名称: | (4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-({N-[(isoquinolin-5-yloxy)acetyl]-S-methyl-L-cysteinyl}amino)-4-phenylbutanoyl]-1,3-thiazolidine-4-carboxamide, protease | | 著者 | Adachi, M, Ohhara, T, Tamada, T, Okazaki, N, Kuroki, R. | | 登録日 | 2009-01-20 | | 公開日 | 2009-03-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | NEUTRON DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of HIV-1 protease in complex with potent inhibitor KNI-272 determined by high-resolution X-ray and neutron crystallography.
Proc.Natl.Acad.Sci.USA, 2009
|
|
3A2O
 | | Crystal Structure of HIV-1 Protease Complexed with KNI-1689 | | 分子名称: | (4R)-3-[(2S,3S)-3-{[(4-amino-2,6-dimethylphenoxy)acetyl]amino}-2-hydroxy-4-phenylbutanoyl]-5,5-dimethyl-N-(2-methylprop -2-en-1-yl)-1,3-thiazolidine-4-carboxamide, GLYCEROL, PROTEASE | | 著者 | Adachi, M, Tamada, T, Hidaka, K, Kimura, T, Kiso, Y, Kuroki, R. | | 登録日 | 2009-05-26 | | 公開日 | 2010-03-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (0.88 Å) | | 主引用文献 | Small-sized human immunodeficiency virus type-1 protease inhibitors containing allophenylnorstatine to explore the S2' pocket.
J.Med.Chem., 52, 2009
|
|
5ZN4
 | | X-ray structure of protein kinase ck2 alpha subunit H148N mutant | | 分子名称: | Casein kinase II subunit alpha, SULFATE ION | | 著者 | Shibazaki, C, Arai, S, Shimizu, R, Kinoshita, T, Kuroki, R, Adachi, M. | | 登録日 | 2018-04-07 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | | 主引用文献 | Hydration Structures of the Human Protein Kinase CK2 alpha Clarified by Joint Neutron and X-ray Crystallography.
J. Mol. Biol., 430, 2018
|
|
5XPF
 | |
5ZN3
 | | X-ray structure of protein kinase ck2 alpha subunit H148S mutant | | 分子名称: | Casein kinase II subunit alpha, SULFATE ION | | 著者 | Shibazaki, C, Arai, S, Shimizu, R, Kinoshita, T, Kuroki, R, Adachi, M. | | 登録日 | 2018-04-07 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Hydration Structures of the Human Protein Kinase CK2 alpha Clarified by Joint Neutron and X-ray Crystallography.
J. Mol. Biol., 430, 2018
|
|
5ZN2
 | | X-ray structure of protein kinase ck2 alpha subunit H148A mutant | | 分子名称: | Casein kinase II subunit alpha, SULFATE ION | | 著者 | Shibazaki, C, Arai, S, Shimizu, R, Kinoshita, T, Kuroki, R, Adachi, M. | | 登録日 | 2018-04-07 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Hydration Structures of the Human Protein Kinase CK2 alpha Clarified by Joint Neutron and X-ray Crystallography.
J. Mol. Biol., 430, 2018
|
|
5ZN1
 | | X-ray structure of protein kinase ck2 alpha subunit in D2O | | 分子名称: | Casein kinase II subunit alpha, SULFATE ION | | 著者 | Shibazaki, C, Arai, S, Shimizu, R, Kinoshita, T, Kuroki, R, Adachi, M. | | 登録日 | 2018-04-07 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Hydration Structures of the Human Protein Kinase CK2 alpha Clarified by Joint Neutron and X-ray Crystallography.
J. Mol. Biol., 430, 2018
|
|
5ZN5
 | | X-ray structure of protein kinase ck2 alpha subunit H148A mutant | | 分子名称: | Casein kinase II subunit alpha, SULFATE ION | | 著者 | Shibazaki, C, Arai, S, Shimizu, R, Kinoshita, T, Kuroki, R, Adachi, M. | | 登録日 | 2018-04-07 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Hydration Structures of the Human Protein Kinase CK2 alpha Clarified by Joint Neutron and X-ray Crystallography.
J. Mol. Biol., 430, 2018
|
|
5YOJ
 | | Structure of A17 HIV-1 Protease in Complex with Inhibitor KNI-1657 | | 分子名称: | (4R)-N-[(2,6-dimethylphenyl)methyl]-3-[(2S,3S)-3-[[(2S)-2-[(7-methoxy-1-benzofuran-2-yl)carbonylamino]-2-[(3R)-oxolan-3 -yl]ethanoyl]amino]-2-oxidanyl-4-phenyl-butanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide, A17 HIV-1 protease, GLYCEROL | | 著者 | Adachi, M, Hidaka, K, Kuroki, R, Kiso, Y. | | 登録日 | 2017-10-29 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Identification of Highly Potent Human Immunodeficiency Virus Type-1 Protease Inhibitors against Lopinavir and Darunavir Resistant Viruses from Allophenylnorstatine-Based Peptidomimetics with P2 Tetrahydrofuranylglycine.
J. Med. Chem., 61, 2018
|
|
5YOK
 | | Structure of HIV-1 Protease in Complex with Inhibitor KNI-1657 | | 分子名称: | (4R)-N-[(2,6-dimethylphenyl)methyl]-3-[(2S,3S)-3-[[(2S)-2-[(7-methoxy-1-benzofuran-2-yl)carbonylamino]-2-[(3R)-oxolan-3 -yl]ethanoyl]amino]-2-oxidanyl-4-phenyl-butanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide, GLYCEROL, HIV-1 PROTEASE | | 著者 | Adachi, M, Hidaka, K, Kuroki, R, Kiso, Y. | | 登録日 | 2017-10-29 | | 公開日 | 2018-07-18 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | | 主引用文献 | Identification of Highly Potent Human Immunodeficiency Virus Type-1 Protease Inhibitors against Lopinavir and Darunavir Resistant Viruses from Allophenylnorstatine-Based Peptidomimetics with P2 Tetrahydrofuranylglycine.
J. Med. Chem., 61, 2018
|
|
5ZN0
 | | Joint X-ray/neutron structure of protein kinase ck2 alpha subunit | | 分子名称: | Casein kinase II subunit alpha, SULFATE ION | | 著者 | Shibazaki, C, Arai, S, Shimizu, R, Kinoshita, T, Ostermann, A, Schrader, T.E, Sunami, T, Kuroki, R, Adachi, M. | | 登録日 | 2018-04-07 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | NEUTRON DIFFRACTION (1.1 Å), X-RAY DIFFRACTION | | 主引用文献 | Hydration Structures of the Human Protein Kinase CK2 alpha Clarified by Joint Neutron and X-ray Crystallography.
J. Mol. Biol., 430, 2018
|
|
5XPE
 | | Neutron structure of the T26H mutant of T4 lysozyme | | 分子名称: | CHLORIDE ION, Endolysin, SODIUM ION | | 著者 | Hiromoto, T, Kuroki, R. | | 登録日 | 2017-06-01 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | NEUTRON DIFFRACTION (1.648 Å), X-RAY DIFFRACTION | | 主引用文献 | Neutron structure of the T26H mutant of T4 phage lysozyme provides insight into the catalytic activity of the mutant enzyme and how it differs from that of wild type.
Protein Sci., 26, 2017
|
|
3VTE
 | | Crystal structure of tetrahydrocannabinolic acid synthase from Cannabis sativa | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, Tetrahydrocannabinolic acid synthase | | 著者 | Shoyama, Y, Tamada, T, Kurihara, K, Takeuchi, A, Taura, F, Arai, S, Blaber, M, Shoyama, Y, Morimoto, S, Kuroki, R. | | 登録日 | 2012-05-28 | | 公開日 | 2012-07-25 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structure and function of 1-tetrahydrocannabinolic acid (THCA) synthase, the enzyme controlling the psychoactivity of Cannabis sativa
J.Mol.Biol., 423, 2012
|
|
3VGS
 | | Wild-type nucleoside diphosphate kinase derived from Halomonas sp. 593 | | 分子名称: | Nucleoside diphosphate kinase | | 著者 | Okazaki, N, Yonezawa, Y, Arai, S, Matsumoto, F, Tamada, T, Tokunaga, H, Ishibashi, M, Tokunaga, M, Kuroki, R. | | 登録日 | 2011-08-20 | | 公開日 | 2012-07-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A structural mechanism for dimeric to tetrameric oligomer conversion in Halomonas sp. nucleoside diphosphate kinase
Protein Sci., 21, 2012
|
|
3WBH
 | | Structural characteristics of alkaline phosphatase from a moderately halophilic bacteria Halomonas sp.593 | | 分子名称: | Alkaline phosphatase, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Arai, S, Yonezawa, Y, Ishibashi, M, Matsumoto, F, Tamada, T, Tokunaga, H, Tokunaga, M, Kuroki, R. | | 登録日 | 2013-05-17 | | 公開日 | 2014-03-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural characteristics of alkaline phosphatase from the moderately halophilic bacterium Halomonas sp. 593.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
3VGU
 | | E134A mutant nucleoside diphosphate kinase derived from Halomonas sp. 593 | | 分子名称: | Nucleoside diphosphate kinase | | 著者 | Okazaki, N, Yonezawa, Y, Arai, S, Matsumoto, F, Tamada, T, Tokunaga, H, Ishibashi, M, Tokunaga, M, Kuroki, R. | | 登録日 | 2011-08-21 | | 公開日 | 2012-07-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A structural mechanism for dimeric to tetrameric oligomer conversion in Halomonas sp. nucleoside diphosphate kinase
Protein Sci., 21, 2012
|
|
3VGE
 | | Crystal structure of glycosyltrehalose trehalohydrolase (D252S) | | 分子名称: | CITRATE ANION, GLYCEROL, Malto-oligosyltrehalose trehalohydrolase | | 著者 | Okazaki, N, Tamada, T, Feese, M.D, Kato, M, Miura, Y, Komeda, T, Kobayashi, K, Kondo, K, Kuroki, R. | | 登録日 | 2011-08-09 | | 公開日 | 2012-06-20 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Substrate recognition mechanism of a glycosyltrehalose trehalohydrolase from Sulfolobus solfataricus KM1.
Protein Sci., 21, 2012
|
|
