1BKD
 
 | | COMPLEX OF HUMAN H-RAS WITH HUMAN SOS-1 | | Descriptor: | H-RAS, SON OF SEVENLESS-1 | | Authors: | Boriack-Sjodin, P.A, Margarit, S.M, Sagi, D.B, Kuriyan, J. | | Deposit date: | 1998-07-06 | | Release date: | 1999-01-13 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The structural basis of the activation of Ras by Sos.
Nature, 394, 1998
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1BK6
 | | KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS | | Descriptor: | KARYOPHERIN ALPHA, LARGE T ANTIGEN | | Authors: | Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J. | | Deposit date: | 1998-07-14 | | Release date: | 1999-01-13 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
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1JG7
 | | T4 phage BGT in complex with UDP and Mn2+ | | Descriptor: | DNA BETA-GLUCOSYLTRANSFERASE, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE | | Authors: | Morera, S, Lariviere, L, Kurzeck, J, Aschke-Sonnenborn, U, Freemont, P.S, Janin, J, Ruger, W. | | Deposit date: | 2001-06-23 | | Release date: | 2001-08-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | High resolution crystal structures of T4 phage beta-glucosyltransferase: induced fit and effect of substrate and metal binding.
J.Mol.Biol., 311, 2001
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1JEJ
 | | T4 phage apo BGT | | Descriptor: | DNA BETA-GLUCOSYLTRANSFERASE | | Authors: | Morera, S, Lariviere, L, Kurzeck, J, Aschke-Sonnenborn, U, Freemont, P.S, Janin, J, Ruger, W. | | Deposit date: | 2001-06-18 | | Release date: | 2001-08-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | High resolution crystal structures of T4 phage beta-glucosyltransferase: induced fit and effect of substrate and metal binding.
J.Mol.Biol., 311, 2001
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1JIU
 | | T4 Phage BGT in Complex with Mg2+ : Form I | | Descriptor: | DNA BETA-GLUCOSYLTRANSFERASE, MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE | | Authors: | Morera, S, Lariviere, L, Kurzeck, J, Aschke-Sonnenborn, U, Freemont, P.S, Janin, J, Ruger, W. | | Deposit date: | 2001-07-03 | | Release date: | 2001-08-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | High resolution crystal structures of T4 phage beta-glucosyltransferase: induced fit and effect of substrate and metal binding.
J.Mol.Biol., 311, 2001
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1AD5
 | | SRC FAMILY KINASE HCK-AMP-PNP COMPLEX | | Descriptor: | CALCIUM ION, HAEMATOPOETIC CELL KINASE HCK, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Sicheri, F, Moarefi, I, Kuriyan, J. | | Deposit date: | 1997-02-20 | | Release date: | 1997-05-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of the Src family tyrosine kinase Hck.
Nature, 385, 1997
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1OPK
 | | Structural basis for the auto-inhibition of c-Abl tyrosine kinase | | Descriptor: | 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ... | | Authors: | Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J. | | Deposit date: | 2003-03-06 | | Release date: | 2003-04-08 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for the autoinhibition of c-Abl tyrosine kinase
Cell(Cambridge,Mass.), 112, 2003
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1A5T
 | | CRYSTAL STRUCTURE OF THE DELTA PRIME SUBUNIT OF THE CLAMP-LOADER COMPLEX OF ESCHERICHIA COLI DNA POLYMERASE III | | Descriptor: | DELTA PRIME, ZINC ION | | Authors: | Guenther, B, Onrust, R, Sali, A, O'Donnell, M, Kuriyan, J. | | Deposit date: | 1998-02-18 | | Release date: | 1998-05-27 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III.
Cell(Cambridge,Mass.), 91, 1997
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1ZMX
 | | Crystal structure of D. melanogaster deoxyribonucleoside kinase N64D mutant in complex with thymidine | | Descriptor: | Deoxynucleoside kinase, SULFATE ION, THYMIDINE | | Authors: | Welin, M, Skovgaard, T, Knecht, W, Berenstein, D, Munch-Petersen, B, Piskur, J, Eklund, H. | | Deposit date: | 2005-05-11 | | Release date: | 2005-05-24 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D.
Febs J., 272, 2005
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1BK5
 | | KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE | | Descriptor: | COBALT (II) ION, KARYOPHERIN ALPHA | | Authors: | Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J. | | Deposit date: | 1998-07-14 | | Release date: | 1999-01-06 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
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1JG6
 | | T4 phage BGT in complex with UDP | | Descriptor: | DNA BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | | Authors: | Morera, S, Lariviere, L, Kurzeck, J, Aschke-Sonnenborn, U, Freemont, P.S, Janin, J, Ruger, W. | | Deposit date: | 2001-06-23 | | Release date: | 2001-08-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | High resolution crystal structures of T4 phage beta-glucosyltransferase: induced fit and effect of substrate and metal binding.
J.Mol.Biol., 311, 2001
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1JIV
 | | T4 phage BGT in complex with Mg2+ : Form II | | Descriptor: | DNA BETA-GLUCOSYLTRANSFERASE, MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE | | Authors: | Morera, S, Lariviere, L, Kurzeck, J, Aschke-Sonnenborn, U, Freemont, P.S, Janin, J, Ruger, W. | | Deposit date: | 2001-07-03 | | Release date: | 2001-08-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | High resolution crystal structures of T4 phage beta-glucosyltransferase: induced fit and effect of substrate and metal binding.
J.Mol.Biol., 311, 2001
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1OPL
 | | Structural basis for the auto-inhibition of c-Abl tyrosine kinase | | Descriptor: | 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, MYRISTIC ACID, proto-oncogene tyrosine-protein kinase | | Authors: | Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J. | | Deposit date: | 2003-03-06 | | Release date: | 2003-04-08 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.42 Å) | | Cite: | Structural basis for the autoinhibition of c-Abl tyrosine kinase
Cell(Cambridge,Mass.), 112, 2003
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2GS7
 | | Crystal Structure of the inactive EGFR kinase domain in complex with AMP-PNP | | Descriptor: | Epidermal growth factor receptor, IODIDE ION, MAGNESIUM ION, ... | | Authors: | Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J. | | Deposit date: | 2006-04-25 | | Release date: | 2006-06-20 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor
Cell(Cambridge,Mass.), 125, 2006
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1EQN
 | | E.COLI PRIMASE CATALYTIC CORE | | Descriptor: | DNA PRIMASE | | Authors: | Podobnik, M, McInerney, P, O'Donnell, M, Kuriyan, J. | | Deposit date: | 2000-04-05 | | Release date: | 2000-06-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | A TOPRIM domain in the crystal structure of the catalytic core of Escherichia coli primase confirms a structural link to DNA topoisomerases.
J.Mol.Biol., 300, 2000
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1JIX
 | | T4 Phage BGT in Complex with Ca2+ | | Descriptor: | CALCIUM ION, DNA BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | | Authors: | Morera, S, Lariviere, L, Kurzeck, J, Aschke-Sonnenborn, U, Freemont, P.S, Janin, J, Ruger, W. | | Deposit date: | 2001-07-03 | | Release date: | 2001-08-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | High resolution crystal structures of T4 phage beta-glucosyltransferase: induced fit and effect of substrate and metal binding.
J.Mol.Biol., 311, 2001
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1ZM7
 | | Crystal structure of D. melanogaster deoxyribonucleoside kinase mutant N64D in complex with dTTP | | Descriptor: | Deoxynucleoside kinase, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE | | Authors: | Welin, M, Skovgaard, T, Knecht, W, Berenstein, D, Munch-Petersen, B, Piskur, J, Eklund, H. | | Deposit date: | 2005-05-10 | | Release date: | 2005-05-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D.
Febs J., 272, 2005
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2FO0
 | | Organization of the SH3-SH2 Unit in Active and Inactive Forms of the c-Abl Tyrosine Kinase | | Descriptor: | 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ... | | Authors: | Nagar, B, Hantschel, O, Seeliger, M, Davies, J.M, Weis, W.I, Superti-Furga, G, Kuriyan, J. | | Deposit date: | 2006-01-12 | | Release date: | 2006-03-21 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase.
Mol.Cell, 21, 2006
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3EEE
 | | Probing the function of heme distortion in the H-NOX family | | Descriptor: | CHLORIDE ION, Methyl-accepting chemotaxis protein, OXYGEN MOLECULE, ... | | Authors: | Olea Jr, C, Boon, E.M, Pellicena, P, Kuriyan, J, Marletta, M.A. | | Deposit date: | 2008-09-04 | | Release date: | 2008-11-25 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Probing the function of heme distortion in the H-NOX family.
Acs Chem.Biol., 3, 2008
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1OT3
 | | Crystal structure of Drosophila deoxyribonucleotide kinase complexed with the substrate deoxythymidine | | Descriptor: | Deoxyribonucleoside Kinase, SULFATE ION, THYMIDINE | | Authors: | Mikkelsen, N.E, Johansson, K, Karlsson, A, Knecht, W, Andersen, G, Piskur, J, Munch-Petersen, B, Eklund, H. | | Deposit date: | 2003-03-21 | | Release date: | 2003-05-27 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Basis for Feedback Inhibition of the Deoxyribonucleoside Salvage Pathway: Studies of the Drosophila Deoxyribonucleoside Kinase.
Biochemistry, 42, 2003
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1NJF
 | | Nucleotide bound form of an isolated E. coli clamp loader gamma subunit | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit gamma, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J. | | Deposit date: | 2002-12-30 | | Release date: | 2003-04-08 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Nucleotide-Induced Conformational Changes in an Isolated Escherichia coli DNA Polymerase III Clamp Loader Subunit
Structure, 11, 2003
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1NVV
 | | Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS | | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J. | | Deposit date: | 2003-02-04 | | Release date: | 2003-04-01 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Structural evidence for feedback activation by RasGTP of the
Ras-specific nucleotide exchange factor SOS
Cell(Cambridge,Mass.), 112, 2003
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1DKG
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1XXI
 | | ADP Bound E. coli Clamp Loader Complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit gamma, DNA polymerase III, ... | | Authors: | Kazmirski, S.L, Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J. | | Deposit date: | 2004-11-05 | | Release date: | 2004-12-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (4.1 Å) | | Cite: | Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex
Proc.Natl.Acad.Sci.USA, 101, 2004
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2RVQ
 | | Solution structure of the isolated histone H2A-H2B heterodimer | | Descriptor: | Histone H2A type 1-B/E, Histone H2B type 1-J | | Authors: | Moriwaki, Y, Yamane, T, Ohtomo, H, Ikeguchi, M, Kurita, J, Sato, M, Nagadoi, A, Shimojo, H, Nishimura, Y. | | Deposit date: | 2016-03-28 | | Release date: | 2016-05-25 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the isolated histone H2A-H2B heterodimer
Sci Rep, 6, 2016
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