8JNB
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![BU of 8jnb by Molmil](/molmil-images/mine/8jnb) | CRAF ras-binding domain chimera, ligand complex | 分子名称: | 2-[4-[[(2S)-1-ethanoyl-3-oxidanylidene-2H-indol-2-yl]methyl]-2-methoxy-phenoxy]ethanamide, RAF proto-oncogene serine/threonine-protein kinase, CRaf | 著者 | Kawamura, T, Kumasaka, T. | 登録日 | 2023-06-06 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Small-molecule RAS/RAF-binding Inhibitors Allosterically Disrupt RAF Conformation and Exert Efficacy Against Broad-spectrum RAS-driven Cancers To Be Published
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8JNA
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![BU of 8jna by Molmil](/molmil-images/mine/8jna) | CRAF ras-binding domain chimera, apo form | 分子名称: | RAF proto-oncogene serine/threonine-protein kinase, CRaf | 著者 | Kawamura, T, Kumasaka, T. | 登録日 | 2023-06-06 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Small-molecule RAS/RAF-binding Inhibitors Allosterically Disrupt RAF Conformation and Exert Efficacy Against Broad-spectrum RAS-driven Cancers To Be Published
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4XIG
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![BU of 4xig by Molmil](/molmil-images/mine/4xig) | Crystal structure of bacterial alginate ABC transporter determined through humid air and glue-coating method | 分子名称: | 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid, AlgM1, AlgM2, ... | 著者 | Kaneko, A, Maruyama, Y, Mizuno, N, Baba, S, Kumasaka, T, Mikami, B, Murata, K, Hashimoto, W. | 登録日 | 2015-01-07 | 公開日 | 2016-01-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.402 Å) | 主引用文献 | A solute-binding protein in the closed conformation induces ATP hydrolysis in a bacterial ATP-binding cassette transporter involved in the import of alginate. J.Biol.Chem., 292, 2017
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3HSB
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![BU of 3hsb by Molmil](/molmil-images/mine/3hsb) | Crystal structure of YmaH (Hfq) from Bacillus subtilis in complex with an RNA aptamer | 分子名称: | Protein hfq, RNA (5'-R(*AP*GP*AP*GP*AP*GP*A)-3') | 著者 | Baba, S, Someya, T, Kumasaka, T, Kawai, G, Nakamura, K. | 登録日 | 2009-06-10 | 公開日 | 2010-06-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of Hfq from Bacillus subtilis in complex with SELEX-derived RNA aptamer: insight into RNA-binding properties of bacterial Hfq Nucleic Acids Res., 40, 2012
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1ERZ
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![BU of 1erz by Molmil](/molmil-images/mine/1erz) | CRYSTAL STRUCTURE OF N-CARBAMYL-D-AMINO ACID AMIDOHYDROLASE WITH A NOVEL CATALYTIC FRAMEWORK COMMON TO AMIDOHYDROLASES | 分子名称: | N-CARBAMYL-D-AMINO ACID AMIDOHYDROLASE | 著者 | Nakai, T, Hasegawa, T, Yamashita, E, Yamamoto, M, Kumasaka, T, Ueki, T, Nanba, H, Ikenaka, Y, Takahashi, S, Sato, M, Tsukihara, T. | 登録日 | 2000-04-06 | 公開日 | 2001-04-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of N-carbamyl-D-amino acid amidohydrolase with a novel catalytic framework common to amidohydrolases. Structure Fold.Des., 8, 2000
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4XTC
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![BU of 4xtc by Molmil](/molmil-images/mine/4xtc) | Crystal structure of bacterial alginate ABC transporter in complex with alginate pentasaccharide-bound periplasmic protein | 分子名称: | AlgM1, AlgM2, AlgQ2, ... | 著者 | Kaneko, A, Maruyama, Y, Mizuno, N, Baba, S, Kumasaka, T, Mikami, B, Murata, K, Hashimoto, W. | 登録日 | 2015-01-23 | 公開日 | 2016-03-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | A solute-binding protein in the closed conformation induces ATP hydrolysis in a bacterial ATP-binding cassette transporter involved in the import of alginate. J.Biol.Chem., 292, 2017
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8IXU
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![BU of 8ixu by Molmil](/molmil-images/mine/8ixu) | |
8IXT
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![BU of 8ixt by Molmil](/molmil-images/mine/8ixt) | |
5B42
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![BU of 5b42 by Molmil](/molmil-images/mine/5b42) | Crystal structure of the C-terminal endonuclease domain of Aquifex aeolicus MutL. | 分子名称: | CADMIUM ION, DI(HYDROXYETHYL)ETHER, DNA mismatch repair protein MutL | 著者 | Fukui, K, Baba, S, Kumasaka, T, Yano, T. | 登録日 | 2016-03-30 | 公開日 | 2016-07-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structural Features and Functional Dependency on beta-Clamp Define Distinct Subfamilies of Bacterial Mismatch Repair Endonuclease MutL J.Biol.Chem., 291, 2016
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4EFM
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![BU of 4efm by Molmil](/molmil-images/mine/4efm) | Crystal structure of H-Ras G12V in complex with GppNHp (state 1) | 分子名称: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Muraoka, S, Shima, F, Araki, M, Inoue, T, Yoshimoto, A, Ijiri, Y, Seki, N, Tamura, A, Kumasaka, T, Yamamoto, M, Kataoka, T. | 登録日 | 2012-03-30 | 公開日 | 2012-05-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of the state 1 conformations of the GTP-bound H-Ras protein and its oncogenic G12V and Q61L mutants Febs Lett., 586, 2012
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4EFN
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![BU of 4efn by Molmil](/molmil-images/mine/4efn) | Crystal structure of H-Ras Q61L in complex with GppNHp (state 1) | 分子名称: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Muraoka, S, Shima, F, Araki, M, Inoue, T, Yoshimoto, A, Ijiri, Y, Seki, N, Tamura, A, Kumasaka, T, Yamamoto, M, Kataoka, T. | 登録日 | 2012-03-30 | 公開日 | 2012-05-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of the state 1 conformations of the GTP-bound H-Ras protein and its oncogenic G12V and Q61L mutants Febs Lett., 586, 2012
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4EFL
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![BU of 4efl by Molmil](/molmil-images/mine/4efl) | Crystal structure of H-Ras WT in complex with GppNHp (state 1) | 分子名称: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Muraoka, S, Shima, F, Araki, M, Inoue, T, Yoshimoto, A, Ijiri, Y, Seki, N, Tamura, A, Kumasaka, T, Yamamoto, M, Kataoka, T. | 登録日 | 2012-03-30 | 公開日 | 2012-05-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of the state 1 conformations of the GTP-bound H-Ras protein and its oncogenic G12V and Q61L mutants Febs Lett., 586, 2012
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8JOF
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![BU of 8jof by Molmil](/molmil-images/mine/8jof) | solution-structure of Ras Binding Domain (RBD) in C-RAF | 分子名称: | RAF proto-oncogene serine/threonine-protein kinase | 著者 | Makino, Y, Matsumoto, S, Yoshikawa, Y, Kawamura, T, Kumasaka, T, Shima, F. | 登録日 | 2023-06-07 | 公開日 | 2024-06-12 | 実験手法 | SOLUTION NMR | 主引用文献 | Small-molecule RAS/RAF-binding Inhibitors Allosterically Disrupt RAF Conformation and Exert Efficacy Against Broad-spectrum RAS-driven Cancers To Be Published
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8JOG
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![BU of 8jog by Molmil](/molmil-images/mine/8jog) | solution structure of Ras Binding Domein (RBD) in C-RAF with negative allosteric modulator. | 分子名称: | RAF proto-oncogene serine/threonine-protein kinase | 著者 | Makino, Y, Matsumoto, S, Yoshikawa, Y, Kawamura, T, Kumasaka, T, Shima, F. | 登録日 | 2023-06-07 | 公開日 | 2024-06-12 | 実験手法 | SOLUTION NMR | 主引用文献 | Small-molecule RAS/RAF-binding Inhibitors Allosterically Disrupt RAF Conformation and Exert Efficacy Against Broad-spectrum RAS-driven Cancers To Be Published
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1VBU
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![BU of 1vbu by Molmil](/molmil-images/mine/1vbu) | Crystal structure of native xylanase 10B from Thermotoga maritima | 分子名称: | ACETIC ACID, GLYCEROL, SULFATE ION, ... | 著者 | Ihsanawati, Kumasaka, T, Kaneko, T, Nakamura, S, Tanaka, N. | 登録日 | 2004-03-02 | 公開日 | 2005-06-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis of the substrate subsite and the highly thermal stability of xylanase 10B from Thermotoga maritima MSB8 Proteins, 61, 2005
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1VBR
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![BU of 1vbr by Molmil](/molmil-images/mine/1vbr) | Crystal structure of complex xylanase 10B from Thermotoga maritima with xylobiose | 分子名称: | ACETIC ACID, alpha-D-xylopyranose-(1-4)-beta-D-xylopyranose, endo-1,4-beta-xylanase B | 著者 | Ihsanawati, Kumasaka, T, Kaneko, T, Nakamura, S, Tanaka, N. | 登録日 | 2004-03-02 | 公開日 | 2005-06-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis of the substrate subsite and the highly thermal stability of xylanase 10B from Thermotoga maritima MSB8 Proteins, 61, 2005
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5GX3
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![BU of 5gx3 by Molmil](/molmil-images/mine/5gx3) | Luciferin-regenerating enzyme collected with serial synchrotron rotational crystallography with accumulated dose of 6.9 MGy (6th measurement) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, Luciferin regenerating enzyme, ... | 著者 | Hasegawa, K, Yamashita, K, Murai, T, Nuemket, N, Hirata, K, Ueno, G, Ago, H, Nakatsu, T, Kumasaka, T, Yamamoto, M. | 登録日 | 2016-09-15 | 公開日 | 2017-01-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Development of a dose-limiting data collection strategy for serial synchrotron rotation crystallography J Synchrotron Radiat, 24, 2017
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5GX5
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![BU of 5gx5 by Molmil](/molmil-images/mine/5gx5) | Luciferin-regenerating enzyme collected with serial synchrotron rotational crystallography with accumulated dose of 26 MGy (23rd measurement) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, Luciferin regenerating enzyme, ... | 著者 | Hasegawa, K, Yamashita, K, Murai, T, Nuemket, N, Hirata, K, Ueno, G, Ago, H, Nakatsu, T, Kumasaka, T, Yamamoto, M. | 登録日 | 2016-09-15 | 公開日 | 2017-01-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Development of a dose-limiting data collection strategy for serial synchrotron rotation crystallography J Synchrotron Radiat, 24, 2017
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5GX2
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![BU of 5gx2 by Molmil](/molmil-images/mine/5gx2) | Luciferin-regenerating enzyme collected with serial synchrotron rotational crystallography with accumulated dose of 3.4 MGy (3rd measurement) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, Luciferin regenerating enzyme, ... | 著者 | Hasegawa, K, Yamashita, K, Murai, T, Nuemket, N, Hirata, K, Ueno, G, Ago, H, Nakatsu, T, Kumasaka, T, Yamamoto, M. | 登録日 | 2016-09-15 | 公開日 | 2017-01-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Development of a dose-limiting data collection strategy for serial synchrotron rotation crystallography J Synchrotron Radiat, 24, 2017
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5GX1
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![BU of 5gx1 by Molmil](/molmil-images/mine/5gx1) | Luciferin-regenerating enzyme collected with serial synchrotron rotational crystallography with accumulated dose of 1.1 MGy (1st measurement) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, Luciferin regenerating enzyme, ... | 著者 | Hasegawa, K, Yamashita, K, Murai, T, Nuemket, N, Hirata, K, Ueno, G, Ago, H, Nakatsu, T, Kumasaka, T, Yamamoto, M. | 登録日 | 2016-09-15 | 公開日 | 2017-01-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Development of a dose-limiting data collection strategy for serial synchrotron rotation crystallography J Synchrotron Radiat, 24, 2017
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5GX4
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![BU of 5gx4 by Molmil](/molmil-images/mine/5gx4) | Luciferin-regenerating enzyme collected with serial synchrotron rotational crystallography with accumulated dose of 14 MGy (12th measurement) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, Luciferin regenerating enzyme, ... | 著者 | Hasegawa, K, Yamashita, K, Murai, T, Nuemket, N, Hirata, K, Ueno, G, Ago, H, Nakatsu, T, Kumasaka, T, Yamamoto, M. | 登録日 | 2016-09-15 | 公開日 | 2017-01-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Development of a dose-limiting data collection strategy for serial synchrotron rotation crystallography J Synchrotron Radiat, 24, 2017
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1WQS
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![BU of 1wqs by Molmil](/molmil-images/mine/1wqs) | Crystal structure of Norovirus 3C-like protease | 分子名称: | 3C-like protease, D(-)-TARTARIC ACID, L(+)-TARTARIC ACID, ... | 著者 | Nakamura, K, Someya, Y, Kumasaka, T, Tanaka, N. | 登録日 | 2004-10-01 | 公開日 | 2005-10-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A norovirus protease structure provides insights into active and substrate binding site integrity J.Virol., 79, 2005
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2D2X
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![BU of 2d2x by Molmil](/molmil-images/mine/2d2x) | Crystal structure of 2-deoxy-scyllo-inosose synthase | 分子名称: | 2-deoxy-scyllo-inosose synthase, COBALT (II) ION, GLYCEROL, ... | 著者 | Nango, E, Kumasaka, T, Tanaka, N, Kakinuma, K, Eguchi, T. | 登録日 | 2005-09-20 | 公開日 | 2006-10-03 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of 2-deoxy-scyllo-inosose synthase, a key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics, in complex with a mechanism-based inhibitor and NAD+ Proteins, 70, 2008
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1UIR
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![BU of 1uir by Molmil](/molmil-images/mine/1uir) | Crystal Structure of Polyamine Aminopropyltransfease from Thermus thermophilus | 分子名称: | Polyamine Aminopropyltransferase | 著者 | Ganbe, T, Ohnuma, M, Sato, T, Kumasaka, T, Oshima, T, Tanaka, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2003-07-18 | 公開日 | 2003-08-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures and enzymatic properties of a triamine/agmatine aminopropyltransferase from Thermus thermophilus J.Mol.Biol., 408, 2011
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1UJ0
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![BU of 1uj0 by Molmil](/molmil-images/mine/1uj0) | Crystal Structure of STAM2 SH3 domain in complex with a UBPY-derived peptide | 分子名称: | PHOSPHATE ION, deubiquitinating enzyme UBPY, signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 著者 | Kaneko, T, Kumasaka, T, Ganbe, T, Sato, T, Miyazawa, K, Kitamura, N, Tanaka, N. | 登録日 | 2003-07-24 | 公開日 | 2003-12-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domain. J.Biol.Chem., 278, 2003
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