3FO7
| Simultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site | 分子名称: | INDOMETHACIN, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION | 著者 | Singh, N, Prem Kumar, R, Sharma, S, Kaur, P, Singh, T.P. | 登録日 | 2008-12-29 | 公開日 | 2009-01-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Simultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site To be Published
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3G8F
| Crystal structure of the complex formed between a group II phospholipase A2 and designed peptide inhibitor carbobenzoxy-dehydro-val-ala-arg-ser at 1.2 A resolution | 分子名称: | PHQ VAL ALA ARG SER peptide, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION | 著者 | Singh, N, Kaur, P, Prem Kumar, R, Somvanshi, R.K, Perbandt, M, Betzel, C, Dey, S, Sharma, S, Singh, T.P. | 登録日 | 2009-02-12 | 公開日 | 2009-03-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Crystal Structure of the Complex Formed between a Group II Phospholipase A2 and Designed Peptide Inhibitor Carbobenzoxy-Dehydro-Val-Ala-Arg-Ser at 1.2 A Resolution To be Published
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3RUQ
| Crystal structure of Cpn-WT in complex with ADP from Methanococcus maripaludis | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperonin, MAGNESIUM ION | 著者 | Pereira, J.H, Ralston, C.Y, Douglas, N.R, Kumar, R, McAndrew, R.P, Knee, K.M, Frydman, J, Adams, P.D. | 登録日 | 2011-05-05 | 公開日 | 2012-01-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.798 Å) | 主引用文献 | Mechanism of nucleotide sensing in group II chaperonins. Embo J., 31, 2012
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4MLW
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3ETA
| Kinase domain of insulin receptor complexed with a pyrrolo pyridine inhibitor | 分子名称: | 1-(3-{5-[4-(aminomethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl}phenyl)-3-(2-phenoxyphenyl)urea, insulin receptor, kinase domain | 著者 | Patnaik, S, Stevens, K, Gerding, R, Deanda, F, Shotwell, B, Tang, J, Hamajima, T, Nakamura, H, Leesnitzer, A, Hassell, A, Shewchuk, L, Kumar, R, Lei, H, Chamberlain, S. | 登録日 | 2008-10-07 | 公開日 | 2009-05-26 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase. Bioorg.Med.Chem.Lett., 19, 2009
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8B9R
| Molecular structure of Cu(II)-bound amyloid-beta monomer implicated in inhibition of peptide self-assembly in Alzheimer's disease | 分子名称: | Amyloid-beta A4 protein, COPPER (II) ION | 著者 | Abelein, A, Ciofi-Baffoni, S, Morman, C, Kumar, R, Giachetti, A, Piccioli, M, Biverstal, H. | 登録日 | 2022-10-06 | 公開日 | 2023-02-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular Structure of Cu(II)-Bound Amyloid-beta Monomer Implicated in Inhibition of Peptide Self-Assembly in Alzheimer's Disease. Jacs Au, 2, 2022
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8B9Q
| Molecular structure of Cu(II)-bound amyloid-beta monomer implicated in inhibition of peptide self-assembly in Alzheimer's disease | 分子名称: | Amyloid-beta A4 protein, COPPER (II) ION | 著者 | Abelein, A, Ciofi-Baffoni, S, Kumar, R, Giachetti, A, Piccioli, M, Biverstal, H. | 登録日 | 2022-10-06 | 公開日 | 2023-02-08 | 最終更新日 | 2024-06-05 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular Structure of Cu(II)-Bound Amyloid-beta Monomer Implicated in Inhibition of Peptide Self-Assembly in Alzheimer's Disease. Jacs Au, 2, 2022
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2H4I
| Crystal structure of the complex of proteolytically produced C-terminal half of bovine lactoferrin with lactose at 2.55 A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | 著者 | Mir, R, Prem kumar, R, Sinha, M, Singh, N, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2006-05-24 | 公開日 | 2006-06-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal structure of the complex of proteolytically produced C-terminal half of bovine lactoferrin with lactose at 2.55 A resolution To be Published
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3EKA
| Crystal structure of the complex of hyaluranidase trimer with ascorbic acid at 3.1 A resolution reveals the locations of three binding sites | 分子名称: | ASCORBIC ACID, Hyaluronidase, phage associated | 著者 | Mishra, P, Ethayathulla, A.S, Prem Kumar, R, Singh, N, Sharma, S, Kaur, P, Bhakuni, V, Singh, T.P. | 登録日 | 2008-09-19 | 公開日 | 2009-09-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Polysaccharide binding sites in hyaluronate lyase--crystal structures of native phage-encoded hyaluronate lyase and its complexes with ascorbic acid and lactose. Febs J., 276, 2009
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6I1T
| Calcium structure of Trichoderma reesei Carbohydrate-Active Enzymes Family AA12 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Turbe-Doan, A, Record, E, Lombard, V, Kumar, R, Henrissat, B, Levasseur, A, Garron, M.L. | 登録日 | 2018-10-30 | 公開日 | 2019-11-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The functional and structural characterization ofTrichoderma reeseidehydrogenase belonging to the PQQ dependent family of Carbohydrate-Active Enzymes Family AA12. Appl.Environ.Microbiol., 2019
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6I1Q
| Iodide structure of Trichoderma reesei Carbohydrate-Active Enzymes Family AA12 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Turbe-Doan, A, Record, E, Lombard, V, Kumar, R, Henrissat, B, Levasseur, A, Garron, M.L. | 登録日 | 2018-10-30 | 公開日 | 2019-11-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | The functional and structural characterization ofTrichoderma reeseidehydrogenase belonging to the PQQ dependent family of Carbohydrate-Active Enzymes Family AA12. Appl.Environ.Microbiol., 2019
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2PGH
| STRUCTURE DETERMINATION OF AQUOMET PORCINE HEMOGLOBIN AT 2.8 ANGSTROM RESOLUTION | 分子名称: | HEMOGLOBIN (AQUO MET) (ALPHA CHAIN), HEMOGLOBIN (AQUO MET) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE | 著者 | Katz, D.S, White, S.P, Huang, W, Kumar, R, Christianson, D.W. | 登録日 | 1994-09-16 | 公開日 | 1994-11-30 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure determination of aquomet porcine hemoglobin at 2.8 A resolution. J.Mol.Biol., 244, 1994
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1AM0
| AMP RNA APTAMER COMPLEX, NMR, 8 STRUCTURES | 分子名称: | ADENOSINE MONOPHOSPHATE, RNA APTAMER | 著者 | Jiang, F, Kumar, R.A, Jones, R.A, Patel, D.J. | 登録日 | 1997-06-19 | 公開日 | 1997-07-23 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis of RNA Folding and Recognition in an AMP-RNA Aptamer Complex Nature, 382, 1996
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7LXD
| Structure of yeast DNA Polymerase Zeta (apo) | 分子名称: | DNA polymerase delta small subunit, DNA polymerase delta subunit 3, DNA polymerase zeta catalytic subunit, ... | 著者 | Truong, C.D, Craig, T.A, Cui, G, Botuyan, M.V, Serkasevich, R.A, Chan, K.-Y, Mer, G, Chiu, P.-L, Kumar, R. | 登録日 | 2021-03-03 | 公開日 | 2021-06-30 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.11 Å) | 主引用文献 | Cryo-EM reveals conformational flexibility in apo DNA polymerase zeta. J.Biol.Chem., 297, 2021
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4YI9
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4YI8
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1A6H
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3I6N
| Mode of Binding of the Tuberculosis Prodrug Isoniazid to Peroxidases: Crystal Structure of Bovine Lactoperoxidase with Isoniazid at 2.7 Resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(DIAZENYLCARBONYL)PYRIDINE, CALCIUM ION, ... | 著者 | Singh, A.K, Kumar, R.P, Pandey, N, Singh, N, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2009-07-07 | 公開日 | 2009-10-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Mode of binding of the tuberculosis prodrug isoniazid to heme peroxidases: binding studies and crystal structure of bovine lactoperoxidase with isoniazid at 2.7 A resolution. J.Biol.Chem., 285, 2010
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4GAA
| Structure of Leukotriene A4 hydrolase from Xenopus laevis complexed with inhibitor bestatin | 分子名称: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, MGC78867 protein, ZINC ION | 著者 | Stsiapanava, A, Kumar, R.B, Haeggstrom, J.Z, Rinaldo-Matthis, A. | 登録日 | 2012-07-25 | 公開日 | 2013-06-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Product formation controlled by substrate dynamics in leukotriene A4 hydrolase. Biochim.Biophys.Acta, 1844, 2014
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1SV3
| Structure of the complex formed between Phospholipase A2 and 4-methoxybenzoic acid at 1.3A resolution. | 分子名称: | 4-METHOXYBENZOIC ACID, Phospholipase A2, SULFATE ION | 著者 | Singh, N, Prahathees, E, Jabeen, T, Pal, A, Ethayathulla, A.S, Prem kumar, R, Sharma, S, Singh, T.P. | 登録日 | 2004-03-27 | 公開日 | 2004-04-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Crystal structures of the complexes of a group IIA phospholipase A2 with two natural anti-inflammatory agents, anisic acid, and atropine reveal a similar mode of binding Proteins, 64, 2006
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4O6Q
| 0.95A resolution structure of the hemophore HasA from Pseudomonas aeruginosa (Y75A mutant) | 分子名称: | FORMIC ACID, HasAp, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Lovell, S, Kumar, R, Battaile, K.P, Matsumura, H, Yao, H, Rodriguez, J.C, Moenne-Loccoz, P, Rivera, M. | 登録日 | 2013-12-23 | 公開日 | 2014-03-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | 主引用文献 | Replacing the Axial Ligand Tyrosine 75 or Its Hydrogen Bond Partner Histidine 83 Minimally Affects Hemin Acquisition by the Hemophore HasAp from Pseudomonas aeruginosa. Biochemistry, 53, 2014
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4O6S
| 1.32A resolution structure of the hemophore HasA from Pseudomonas aeruginosa (H83A mutant, Zinc Bound) | 分子名称: | 1,2-ETHANEDIOL, HasAp, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Lovell, S, Kumar, R, Battaile, K.P, Matsumura, H, Yao, H, Rodriguez, J.C, Moenne-Loccoz, P, Rivera, M. | 登録日 | 2013-12-23 | 公開日 | 2014-03-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | Replacing the Axial Ligand Tyrosine 75 or Its Hydrogen Bond Partner Histidine 83 Minimally Affects Hemin Acquisition by the Hemophore HasAp from Pseudomonas aeruginosa. Biochemistry, 53, 2014
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4O6T
| 1.25A resolution structure of the hemophore HasA from Pseudomonas aeruginosa (H83A mutant, pH 5.4) | 分子名称: | 1,2-ETHANEDIOL, HasAp, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Lovell, S, Kumar, R, Battaile, K.P, Matsumura, H, Yao, H, Rodriguez, J.C, Moenne-Loccoz, P, Rivera, M. | 登録日 | 2013-12-23 | 公開日 | 2014-03-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Replacing the Axial Ligand Tyrosine 75 or Its Hydrogen Bond Partner Histidine 83 Minimally Affects Hemin Acquisition by the Hemophore HasAp from Pseudomonas aeruginosa. Biochemistry, 53, 2014
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4O6U
| 0.89A resolution structure of the hemophore HasA from Pseudomonas aeruginosa (H83A mutant) | 分子名称: | 1,2-ETHANEDIOL, HasAp, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Lovell, S, Kumar, R, Battaile, K.P, Matsumura, H, Yao, H, Rodriguez, J.C, Moenne-Loccoz, P, Rivera, M. | 登録日 | 2013-12-23 | 公開日 | 2014-03-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (0.89 Å) | 主引用文献 | Replacing the Axial Ligand Tyrosine 75 or Its Hydrogen Bond Partner Histidine 83 Minimally Affects Hemin Acquisition by the Hemophore HasAp from Pseudomonas aeruginosa. Biochemistry, 53, 2014
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1BIV
| BOVINE IMMUNODEFICIENCY VIRUS TAT-TAR COMPLEX, NMR, 5 STRUCTURES | 分子名称: | TAR RNA, TAT PEPTIDE | 著者 | Ye, X, Kumar, R.A, Patel, D.J. | 登録日 | 1996-06-12 | 公開日 | 1996-12-23 | 最終更新日 | 2024-04-10 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular recognition in the bovine immunodeficiency virus Tat peptide-TAR RNA complex. Chem.Biol., 2, 1995
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