4GAA
Structure of Leukotriene A4 hydrolase from Xenopus laevis complexed with inhibitor bestatin
Summary for 4GAA
| Entry DOI | 10.2210/pdb4gaa/pdb |
| Descriptor | MGC78867 protein, ZINC ION, 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, ... (4 entities in total) |
| Functional Keywords | leukotriene a4 hydrolase, metalloprotein, hydrolase, protease, zinc binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Xenopus laevis (clawed frog,common platanna,platanna) |
| Total number of polymer chains | 2 |
| Total formula weight | 138945.66 |
| Authors | Stsiapanava, A.,Kumar, R.B.,Haeggstrom, J.Z.,Rinaldo-Matthis, A. (deposition date: 2012-07-25, release date: 2013-06-12, Last modification date: 2024-02-28) |
| Primary citation | Stsiapanava, A.,Tholander, F.,Kumar, R.B.,Qureshi, A.A.,Niegowski, D.,Hasan, M.,Thunnissen, M.,Haeggstrom, J.Z.,Rinaldo-Matthis, A. Product formation controlled by substrate dynamics in leukotriene A4 hydrolase. Biochim.Biophys.Acta, 1844:439-446, 2014 Cited by PubMed: 24333438DOI: 10.1016/j.bbapap.2013.12.003 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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