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PDB: 71 件

3ZOT
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Structure of E.coli rhomboid protease GlpG in complex with monobactam L29 (data set 2)
分子名称: CHLORIDE ION, RHOMBOID PROTEASE GLPG, nonyl beta-D-glucopyranoside, ...
著者Vinothkumar, K.R, Pierrat, O.A, Large, J.M, Freeman, M.
登録日2013-02-24
公開日2013-05-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献Structure of Rhomboid Protease in Complex with Beta-Lactam Inhibitors Defines the S2' Cavity.
Structure, 21, 2013
3ZMH
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Structure of E.coli rhomboid protease GlpG in complex with monobactam L62
分子名称: CHLORIDE ION, CYCLOPENTYL 2-OXO-4-PHENYLAZETIDINE-1-CARBOXYLATE, RHOMBOID PROTEASE GLPG, ...
著者Vinothkumar, K.R, Pierrat, O.A, Large, J.M, Freeman, M.
登録日2013-02-11
公開日2013-05-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of rhomboid protease in complex with beta-lactam inhibitors defines the S2' cavity.
Structure, 21, 2013
3ZMJ
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Structure of E.coli rhomboid protease GlpG in complex with monobactam L61
分子名称: 2-methylpropyl N-[(1R)-3-oxidanylidene-1-phenyl-propyl]carbamate, CHLORIDE ION, RHOMBOID PROTEASE GLPG, ...
著者Vinothkumar, K.R, Pierrat, O, Large, J.M, Freeman, M.
登録日2013-02-11
公開日2013-05-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of Rhomboid Protease in Complex with Beta-Lactam Inhibitors Defines the S2' Cavity.
Structure, 21, 2013
3ZEB
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A complex of GlpG with isocoumarin inhibitor covalently bonded to serine 201 and histidine 150
分子名称: 2-phenylethyl 2-(4-azanyl-2-methanoyl-phenyl)ethanoate, CHLORIDE ION, RHOMBOID PROTEASE GLPG, ...
著者Vinothkumar, K.R, voskya, O, Kuettler, E.V, Brouwer, A.J, Liskamp, R.M.J, Verhelst, S.H.L.
登録日2012-12-04
公開日2013-02-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Activity-Based Probes for Rhomboid Proteases Discovered in a Mass Spectrometry-Based Assay.
Proc.Natl.Acad.Sci.USA, 110, 2013
4CKD
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BU of 4ckd by Molmil
Model of complex between the E.coli enzyme beta-galactosidase and four single chain Fv antibody domains scFv13R4.
分子名称: BETA-GALACTOSIDASE, SCFV13R4 ANTIBODY FV HEAVY CHAIN, SCFV13R4 ANTIBODY FV LIGHT CHAIN
著者Vinothkumar, K.R, McMullan, G, Henderson, R.
登録日2014-01-03
公開日2014-01-15
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (13 Å)
主引用文献Molecular Mechanism of Antibody-Mediated Activation of Beta-Galactosidase.
Structure, 22, 2014
3ZMI
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BU of 3zmi by Molmil
Structure of E.coli rhomboid protease GlpG in complex with monobactam L29
分子名称: RHOMBOID PROTEASE GLPG, nonyl beta-D-glucopyranoside, phenyl N-[(1R)-3-oxidanylidene-1-phenyl-propyl]carbamate
著者Vinothkumar, K.R, Pierrat, O.A, Large, J.M, Freeman, M.
登録日2013-02-11
公開日2013-05-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Rhomboid Protease in Complex with Beta-Lactam Inhibitors Defines the S2' Cavity.
Structure, 21, 2013
7W8J
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Dimethylformamidase, 2x(A2B2)
分子名称: FE (III) ION, N,N-dimethylformamidase large subunit, N,N-dimethylformamidase small subunit
著者Vinothkumar, K.R, Subramanian, R, Arya, C, Ramanathan, G.
登録日2021-12-07
公開日2022-04-06
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Dimethylformamidase with a Unique Iron Center
To Be Published
5LDX
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Structure of mammalian respiratory Complex I, class3.
分子名称: Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ...
著者Vinothkumar, K.R, Zhu, J, Hirst, J.
登録日2016-06-28
公開日2016-09-14
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Structure of mammalian respiratory complex I.
Nature, 536, 2016
5LQY
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BU of 5lqy by Molmil
Structure of F-ATPase from Pichia angusta, in state2
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase OSCP subunit, ...
著者Vinothkumar, K.R, Montgomery, M.G, Liu, S, Walker, J.E.
登録日2016-08-17
公開日2016-11-16
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Structure of the mitochondrial ATP synthase fromPichia angustadetermined by electron cryo-microscopy.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5LQX
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BU of 5lqx by Molmil
Structure of F-ATPase from Pichia angusta, state3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase AAP1 subunit, ...
著者Vinothkumar, K.R, Montgomery, M.G, Liu, S, Walker, J.E.
登録日2016-08-17
公開日2016-11-16
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Structure of the mitochondrial ATP synthase fromPichia angustadetermined by electron cryo-microscopy.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5LDW
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BU of 5ldw by Molmil
Structure of mammalian respiratory Complex I, class1
分子名称: Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ...
著者Vinothkumar, K.R, Zhu, J, Hirst, J.
登録日2016-06-28
公開日2016-09-07
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (4.27 Å)
主引用文献Structure of mammalian respiratory complex I.
Nature, 536, 2016
5LC5
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BU of 5lc5 by Molmil
Structure of mammalian respiratory Complex I, class2
分子名称: Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ...
著者Vinothkumar, K.R, Zhu, J, Hirst, J.
登録日2016-06-19
公開日2016-09-07
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.35 Å)
主引用文献Structure of mammalian respiratory complex I.
Nature, 536, 2016
5LQZ
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BU of 5lqz by Molmil
Structure of F-ATPase from Pichia angusta, state1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase OSCP subunit, ...
著者Vinothkumar, K.R, Montgomery, M.G, Liu, S, Walker, J.E.
登録日2016-08-17
公開日2016-11-16
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Structure of the mitochondrial ATP synthase fromPichia angustadetermined by electron cryo-microscopy.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5MT6
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BU of 5mt6 by Molmil
Structure of E.coli GlpG in complex with peptide derived inhibitor Ac-RVRHA-phenylethyl-ketoamide
分子名称: ACE-ARG-VAL-ARG-HIS-ALA-V9C, Rhomboid protease GlpG, nonyl beta-D-glucopyranoside
著者Vinothkumar, K.R.
登録日2017-01-06
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献General and Modular Strategy for Designing Potent, Selective, and Pharmacologically Compliant Inhibitors of Rhomboid Proteases.
Cell Chem Biol, 24, 2017
5MT8
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BU of 5mt8 by Molmil
Structure of E.coli GlpG in complex with peptide derived inhibitor Ac-RVRHA-cmk
分子名称: ACE-ARG-VAL-ARG-HIS-ALA-0QE, CHLORIDE ION, Rhomboid protease GlpG, ...
著者Vinothkumar, K.R.
登録日2017-01-06
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献General and Modular Strategy for Designing Potent, Selective, and Pharmacologically Compliant Inhibitors of Rhomboid Proteases.
Cell Chem Biol, 24, 2017
5MT7
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BU of 5mt7 by Molmil
Structure of E.coli GlpG in complex with peptide derived inhibitor Ac-VRHA-cmk
分子名称: ACE-VAL-ARG-HIS-ALA-0QE, Rhomboid protease GlpG
著者Vinothkumar, K.R.
登録日2017-01-06
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献General and Modular Strategy for Designing Potent, Selective, and Pharmacologically Compliant Inhibitors of Rhomboid Proteases.
Cell Chem Biol, 24, 2017
4UQ8
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BU of 4uq8 by Molmil
Electron cryo-microscopy of bovine Complex I
分子名称: ACYL CARRIER PROTEIN, MITOCHONDRIAL, FE2/S2 (INORGANIC) CLUSTER, ...
著者Vinothkumar, K.R, Zhu, J, Hirst, J.
登録日2014-06-21
公開日2014-10-01
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.95 Å)
主引用文献Architecture of Mammalian Respiratory Complex I.
Nature, 515, 2014
2XOW
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BU of 2xow by Molmil
Structure of GlpG in complex with a mechanism-based isocoumarin inhibitor
分子名称: 5-AMINO-2-(2-METHOXY-2-OXOETHYL)BENZOIC ACID, RHOMBOID PROTEASE GLPG, nonyl beta-D-glucopyranoside
著者Vinothkumar, K.R, Strisovsky, K, Andreeva, A, Christova, Y, Verhelst, S, Freeman, M.
登録日2010-08-24
公開日2010-10-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The Structural Basis for Catalysis and Substrate Specificity of a Rhomboid Protease
Embo J., 29, 2010
2XOV
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BU of 2xov by Molmil
Crystal Structure of E.coli rhomboid protease GlpG, native enzyme
分子名称: GLYCEROL, RHOMBOID PROTEASE GLPG, nonyl beta-D-glucopyranoside
著者Vinothkumar, K.R, Strisovsky, K, Andreeva, A, Christova, Y, Verhelst, S, Freeman, M.
登録日2010-08-24
公開日2010-10-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The structural basis for catalysis and substrate specificity of a rhomboid protease.
EMBO J., 29, 2010
2XTU
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BU of 2xtu by Molmil
Structure of E.coli rhomboid protease GlpG active site mutant, S201T in trigonal crystal form
分子名称: RHOMBOID PROTEASE GLPG, nonyl beta-D-glucopyranoside
著者Vinothkumar, K.R.
登録日2010-10-12
公開日2011-02-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of Rhomboid Protease in a Lipid Environment
J.Mol.Biol., 407, 2011
2XTV
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BU of 2xtv by Molmil
Structure of E.coli rhomboid protease GlpG, active site mutant, S201T, orthorhombic crystal form
分子名称: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, RHOMBOID PROTEASE GLPG
著者Vinothkumar, K.R.
登録日2010-10-12
公開日2011-02-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of rhomboid protease in a lipid environment.
J. Mol. Biol., 407, 2011
7FD9
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BU of 7fd9 by Molmil
Thermostabilised full length human mGluR5-5M with orthosteric antagonist, LY341495
分子名称: 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5
著者Vinothkumar, K.R, Cannone, G, Lebon, G.
登録日2021-07-16
公開日2021-09-08
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations.
Cell Rep, 36, 2021
7FD8
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BU of 7fd8 by Molmil
Thermostabilised full length human mGluR5-5M bound with L-quisqualic acid
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
著者Vinothkumar, K.R, Cannone, G, Lebon, G.
登録日2021-07-16
公開日2021-09-08
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations.
Cell Rep, 36, 2021
3BOY
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BU of 3boy by Molmil
Crystal structure of the HutP antitermination complex bound to the HUT mRNA
分子名称: 5'-R(*UP*UP*UP*AP*GP*UP*UP*UP*UP*UP*AP*GP*UP*UP*UP*UP*UP*AP*GP*UP*UP*U)-3', HISTIDINE, Hut operon positive regulatory protein, ...
著者Kumarevel, T.S, Balasundaresan, D, Jeyakanthan, J, Shinkai, A, Yokoyama, S, Kumar, P.K.R, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-12-18
公開日2008-01-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of HutP complexed with the 55-mer RNA
To be Published
1WRQ
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BU of 1wrq by Molmil
Crystal Structure of HutP-Antitermination complex
分子名称: 5'-R(*UP*UP*UP*AP*GP*UP*U)-3', HISTIDINE, Hut operon positive regulatory protein, ...
著者Kumarevel, T, Mizuno, H, Kumar, P.K.R.
登録日2004-10-25
公開日2005-08-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the HutP-antitermination complex
To be published

 

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