7U8K
| Magic Angle Spinning NMR Structure of Human Cofilin-2 Assembled on Actin Filaments | Descriptor: | Actin, alpha skeletal muscle, Cofilin-2 | Authors: | Kraus, J, Russell, R, Kudryashova, E, Xu, C, Katyal, N, Kudryashov, D, Perilla, J.R, Polenova, T. | Deposit date: | 2022-03-08 | Release date: | 2023-08-16 | Last modified: | 2024-02-28 | Method: | SOLID-STATE NMR | Cite: | Magic angle spinning NMR structure of human cofilin-2 assembled on actin filaments reveals isoform-specific conformation and binding mode. Nat Commun, 13, 2022
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7M0G
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1JBQ
| STRUCTURE OF HUMAN CYSTATHIONINE BETA-SYNTHASE: A UNIQUE PYRIDOXAL 5'-PHOSPHATE DEPENDENT HEMEPROTEIN | Descriptor: | CYSTATHIONINE BETA-SYNTHASE, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Meier, M, Janosik, M, Kery, V, Kraus, J.P, Burkhard, P. | Deposit date: | 2001-06-06 | Release date: | 2001-08-12 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of human cystathionine beta-synthase: a unique pyridoxal 5'-phosphate-dependent heme protein. EMBO J., 20, 2001
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5OHX
| Structure of active cystathionine B-synthase from Apis mellifera | Descriptor: | Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Gimenez-Mascarell, P, Majtan, T, Oyenarte, I, Ereno-Orbea, J, Majtan, J, Kraus, J.P, Klaudiny, J, Martinez-Cruz, L.A. | Deposit date: | 2017-07-18 | Release date: | 2018-01-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of cystathionine beta-synthase from honeybee Apis mellifera. J. Struct. Biol., 202, 2018
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4L28
| Crystal structure of delta516-525 human cystathionine beta-synthase D444N mutant containing C-terminal 6xHis tag | Descriptor: | Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Ereno, J, Majtan, T, Oyenarte, I, Kraus, J.P, Martinez, L.A. | Deposit date: | 2013-06-04 | Release date: | 2013-09-18 | Last modified: | 2013-10-16 | Method: | X-RAY DIFFRACTION (2.626 Å) | Cite: | Structural basis of regulation and oligomerization of human cystathionine beta-synthase, the central enzyme of transsulfuration. Proc.Natl.Acad.Sci.USA, 110, 2013
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4L27
| Crystal structure of delta1-39 and delta516-525 human cystathionine beta-synthase D444N mutant containing C-terminal 6xHis tag | Descriptor: | Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Ereno, J, Majtan, T, Oyenarte, I, Kraus, J.P, Martinez, L.A. | Deposit date: | 2013-06-04 | Release date: | 2013-09-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.391 Å) | Cite: | Structural basis of regulation and oligomerization of human cystathionine beta-synthase, the central enzyme of transsulfuration. Proc.Natl.Acad.Sci.USA, 110, 2013
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4L0D
| Crystal structure of delta516-525 human cystathionine beta-synthase containing C-terminal 6xHis-tag | Descriptor: | Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Ereno, J, Majtan, T, Oyenarte, I, Kraus, J.P, Martinez-Cruz, L.A. | Deposit date: | 2013-05-31 | Release date: | 2013-09-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Structural basis of regulation and oligomerization of human cystathionine beta-synthase, the central enzyme of transsulfuration. Proc.Natl.Acad.Sci.USA, 110, 2013
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4L3V
| Crystal structure of delta516-525 human cystathionine beta-synthase | Descriptor: | Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Ereno, J, Majtan, T, Oyenarte, I, Kraus, J.P, Martinez, L.A. | Deposit date: | 2013-06-07 | Release date: | 2013-09-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.628 Å) | Cite: | Structural basis of regulation and oligomerization of human cystathionine beta-synthase, the central enzyme of transsulfuration. Proc.Natl.Acad.Sci.USA, 110, 2013
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4PCU
| Crystal structure of delta516-525 E201S human cystathionine beta-synthase with AdoMet | Descriptor: | Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Ereno-Orbea, J, Majtan, T, Oyenarte, I, Kraus, J.P, Martinez-Cruz, L.A. | Deposit date: | 2014-04-16 | Release date: | 2014-09-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.578 Å) | Cite: | Structural insight into the molecular mechanism of allosteric activation of human cystathionine beta-synthase by S-adenosylmethionine. Proc.Natl.Acad.Sci.USA, 111, 2014
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3TIK
| Sterol 14-alpha demethylase (CYP51) from Trypanosoma brucei in complex with the tipifarnib derivative 6-((4-chlorophenyl)(methoxy)(1-methyl-1H-imidazol-5-yl)methyl)-4-(2,6-difluorophenyl)-1-methylquinolin-2(1H)-one | Descriptor: | 6-[(R)-(4-chlorophenyl)(methoxy)(1-methyl-1H-imidazol-5-yl)methyl]-4-(2,6-difluorophenyl)-1-methylquinolin-2(1H)-one, PROTOPORPHYRIN IX CONTAINING FE, sterol 14-alpha demethylase (CYP51) | Authors: | Hargrove, T.Y, Wawrzak, Z, Kraus, J.M, Gelb, M.H, Buckner, F.S, Waterman, M.R, Lepesheva, G.I. | Deposit date: | 2011-08-20 | Release date: | 2012-07-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Pharmacological characterization, structural studies, and in vivo activities of anti-chagas disease lead compounds derived from tipifarnib. Antimicrob.Agents Chemother., 56, 2012
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