2RQC
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![BU of 2rqc by Molmil](/molmil-images/mine/2rqc) | Solution Structure of RNA-binding domain 3 of CUGBP1 in complex with RNA (UG)3 | Descriptor: | 5'-R(*UP*GP*UP*GP*UP*G)-3', CUG-BP- and ETR-3-like factor 1 | Authors: | Tsuda, K, Kuwasako, K, Takahashi, M, Someya, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2009-04-09 | Release date: | 2009-08-04 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural basis for the sequence-specific RNA-recognition mechanism of human CUG-BP1 RRM3 Nucleic Acids Res., 37, 2009
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3VYW
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![BU of 3vyw by Molmil](/molmil-images/mine/3vyw) | Crystal structure of MNMC2 from Aquifex Aeolicus | Descriptor: | BENZAMIDINE, MNMC2, S-ADENOSYLMETHIONINE | Authors: | Shibata, R, Bessho, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2012-10-03 | Release date: | 2012-10-17 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Characterization and structure of the Aquifex aeolicus protein DUF752: a bacterial tRNA-methyltransferase (MnmC2) functioning without the usually fused oxidase domain (MnmC1). J.Biol.Chem., 287, 2012
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3WE4
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![BU of 3we4 by Molmil](/molmil-images/mine/3we4) | |
3CQ1
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![BU of 3cq1 by Molmil](/molmil-images/mine/3cq1) | Structure of the DTDP-4-Keto-L-Rhamnose Reductase related protein (TT1362) from Thermus Thermophilus HB8 | Descriptor: | Putative uncharacterized protein TTHB138 | Authors: | Jeyakanthan, J, Satoh, S, Kitamura, Y, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-04-02 | Release date: | 2009-04-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the DTDP-4-Keto-L-Rhamnose Reductase related protein (TT1362) from Thermus Thermophilus HB8 To be Published
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3WF6
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![BU of 3wf6 by Molmil](/molmil-images/mine/3wf6) | Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative 4-[4-(1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]-1H-pyrazolo[3,4-d]pyrimidine | Descriptor: | 4-[4-(1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]-1H-pyrazolo[3,4-d]pyrimidine, Ribosomal protein S6 kinase beta-1, ZINC ION | Authors: | Niwa, H, Shirouzu, M, Yokoyama, S. | Deposit date: | 2013-07-17 | Release date: | 2014-08-06 | Last modified: | 2014-10-29 | Method: | X-RAY DIFFRACTION (2.031 Å) | Cite: | Crystal structures of the S6K1 kinase domain in complexes with inhibitors J.Struct.Funct.Genom., 15, 2014
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3WNC
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![BU of 3wnc by Molmil](/molmil-images/mine/3wnc) | Crystal structure of EF-Pyl in complex with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein translation elongation factor 1A | Authors: | Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2013-12-08 | Release date: | 2014-12-10 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.). J. Struct. Funct. Genomics, 16, 2015
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3WNB
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![BU of 3wnb by Molmil](/molmil-images/mine/3wnb) | Crystal structure of EF-Pyl in complex with GMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein translation elongation factor 1A | Authors: | Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2013-12-08 | Release date: | 2014-12-10 | Last modified: | 2020-05-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.). J. Struct. Funct. Genomics, 16, 2015
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3W9Y
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![BU of 3w9y by Molmil](/molmil-images/mine/3w9y) | Crystal structure of the human DLG1 guanylate kinase domain | Descriptor: | Disks large homolog 1 | Authors: | Mori, S, Tezuka, Y, Arakawa, A, Handa, N, Shirouzu, M, Akiyama, T, Yokoyama, S. | Deposit date: | 2013-04-18 | Release date: | 2013-06-26 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the guanylate kinase domain from discs large homolog 1 (DLG1/SAP97) Biochem.Biophys.Res.Commun., 435, 2013
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3WF7
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![BU of 3wf7 by Molmil](/molmil-images/mine/3wf7) | Crystal structure of S6K1 kinase domain in complex with a purine derivative 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide | Descriptor: | 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide, GLYCEROL, Ribosomal protein S6 kinase beta-1, ... | Authors: | Niwa, H, Shirouzu, M, Yokoyama, S. | Deposit date: | 2013-07-17 | Release date: | 2014-08-06 | Last modified: | 2014-10-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structures of the S6K1 kinase domain in complexes with inhibitors J.Struct.Funct.Genom., 15, 2014
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3WF5
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![BU of 3wf5 by Molmil](/molmil-images/mine/3wf5) | Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine | Descriptor: | 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine, Ribosomal protein S6 kinase beta-1, ZINC ION | Authors: | Niwa, H, Shirouzu, M, Yokoyama, S. | Deposit date: | 2013-07-17 | Release date: | 2014-08-06 | Last modified: | 2014-10-29 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | Crystal structures of the S6K1 kinase domain in complexes with inhibitors J.Struct.Funct.Genom., 15, 2014
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3WHE
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![BU of 3whe by Molmil](/molmil-images/mine/3whe) | A new conserved neutralizing epitope at the globular head of hemagglutinin in H3N2 influenza viruses | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Fujii, Y, Sumida, T, Shirouzu, M, Yokoyama, S. | Deposit date: | 2013-08-25 | Release date: | 2014-04-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Conserved neutralizing epitope at globular head of hemagglutinin in H3N2 influenza viruses. J.Virol., 88, 2014
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1NZ9
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![BU of 1nz9 by Molmil](/molmil-images/mine/1nz9) | Solution Structure of the N-utilization substance G (NusG) C-terminal (NGC) domain from Thermus thermophilus | Descriptor: | TRANSCRIPTION ANTITERMINATION PROTEIN NUSG | Authors: | Reay, P, Yamasaki, K, Terada, T, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-02-17 | Release date: | 2004-04-06 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural and sequence comparisons arising from the solution structure of the transcription elongation factor NusG from Thermus thermophilus Proteins, 56, 2004
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8IFJ
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![BU of 8ifj by Molmil](/molmil-images/mine/8ifj) | |
3WCO
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![BU of 3wco by Molmil](/molmil-images/mine/3wco) | |
3WCN
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![BU of 3wcn by Molmil](/molmil-images/mine/3wcn) | |
5H12
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1PMS
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![BU of 1pms by Molmil](/molmil-images/mine/1pms) | PLECKSTRIN HOMOLOGY DOMAIN OF SON OF SEVENLESS 1 (SOS1) WITH GLYCINE-SERINE ADDED TO THE N-TERMINUS, NMR, 20 STRUCTURES | Descriptor: | SOS 1 | Authors: | Koshiba, S, Kigawa, T, Kim, J, Shirouzu, M, Bowtell, D, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 1997-02-18 | Release date: | 1997-05-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The solution structure of the pleckstrin homology domain of mouse Son-of-sevenless 1 (mSos1). J.Mol.Biol., 269, 1997
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3WF8
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![BU of 3wf8 by Molmil](/molmil-images/mine/3wf8) | Crystal structure of S6K1 kinase domain in complex with a quinoline derivative 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carboxylate | Descriptor: | 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carboxylate, GLYCEROL, Ribosomal protein S6 kinase beta-1, ... | Authors: | Niwa, H, Shirouzu, M, Yokoyama, S. | Deposit date: | 2013-07-17 | Release date: | 2014-08-06 | Last modified: | 2014-10-29 | Method: | X-RAY DIFFRACTION (1.975 Å) | Cite: | Crystal structures of the S6K1 kinase domain in complexes with inhibitors J.Struct.Funct.Genom., 15, 2014
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1QQT
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![BU of 1qqt by Molmil](/molmil-images/mine/1qqt) | METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI | Descriptor: | METHIONYL-TRNA SYNTHETASE, ZINC ION | Authors: | Mechulam, Y, Schmitt, E, Maveyraud, L, Zelwer, C, Nureki, O, Yokoyama, S, Konno, M, Blanquet, S. | Deposit date: | 1999-06-08 | Release date: | 2000-01-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features. J.Mol.Biol., 294, 1999
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5AYF
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![BU of 5ayf by Molmil](/molmil-images/mine/5ayf) | Crystal structure of SET7/9 in complex with cyproheptadine | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(dibenzo[1,2-a:2',1'-d][7]annulen-11-ylidene)-1-methyl-piperidine, Histone-lysine N-methyltransferase SETD7, ... | Authors: | Niwa, H, Handa, N, Takemoto, Y, Ito, A, Tomabechi, Y, Umehara, T, Shirouzu, M, Yoshida, M, Yokoyama, S. | Deposit date: | 2015-08-20 | Release date: | 2016-04-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.005 Å) | Cite: | Identification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent Transcription J.Med.Chem., 59, 2016
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5X50
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![BU of 5x50 by Molmil](/molmil-images/mine/5x50) | RNA Polymerase II from Komagataella Pastoris (Type-2 crystal) | Descriptor: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit, ... | Authors: | Ehara, H, Umehara, T, Sekine, S, Yokoyama, S. | Deposit date: | 2017-02-14 | Release date: | 2017-05-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (4.293 Å) | Cite: | Crystal structure of RNA polymerase II from Komagataella pastoris Biochem. Biophys. Res. Commun., 487, 2017
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5X51
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![BU of 5x51 by Molmil](/molmil-images/mine/5x51) | RNA Polymerase II from Komagataella Pastoris (Type-3 crystal) | Descriptor: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit, ... | Authors: | Ehara, H, Umehara, T, Sekine, S, Yokoyama, S. | Deposit date: | 2017-02-14 | Release date: | 2017-05-17 | Method: | X-RAY DIFFRACTION (6.996 Å) | Cite: | Crystal structure of RNA polymerase II from Komagataella pastoris Biochem. Biophys. Res. Commun., 487, 2017
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3UFZ
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![BU of 3ufz by Molmil](/molmil-images/mine/3ufz) | Crystal structure of a Trp-less green fluorescent protein translated by the universal genetic code | Descriptor: | Green fluorescent protein | Authors: | Kawahara-Kobayashi, A, Araiso, Y, Matsuda, T, Yokoyama, S, Kigawa, T, Nureki, O, Kiga, D. | Deposit date: | 2011-11-02 | Release date: | 2012-10-17 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Simplification of the genetic code: restricted diversity of genetically encoded amino acids. Nucleic Acids Res., 40, 2012
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5X4Z
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![BU of 5x4z by Molmil](/molmil-images/mine/5x4z) | RNA Polymerase II from Komagataella Pastoris (Type-1 crystal) | Descriptor: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit, ... | Authors: | Ehara, H, Umehara, T, Sekine, S, Yokoyama, S. | Deposit date: | 2017-02-14 | Release date: | 2017-05-17 | Method: | X-RAY DIFFRACTION (7.8 Å) | Cite: | Crystal structure of RNA polymerase II from Komagataella pastoris Biochem. Biophys. Res. Commun., 487, 2017
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3WND
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![BU of 3wnd by Molmil](/molmil-images/mine/3wnd) | Crystal structure of EF-Pyl | Descriptor: | CITRIC ACID, Protein translation elongation factor 1A | Authors: | Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2013-12-08 | Release date: | 2014-12-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.). J. Struct. Funct. Genomics, 16, 2015
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