6DKS
 
 | | Structure of the Rbpj-SHARP-DNA Repressor Complex | | 分子名称: | DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), Maltose/maltodextrin-binding periplasmic protein, ... | | 著者 | Kovall, R.A, VanderWielen, B.D, Yuan, Z. | | 登録日 | 2018-05-30 | | 公開日 | 2019-01-02 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | Structural and Functional Studies of the RBPJ-SHARP Complex Reveal a Conserved Corepressor Binding Site.
Cell Rep, 26, 2019
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5E24
 | | Structure of the Su(H)-Hairless-DNA Repressor Complex | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), ... | | 著者 | Kovall, R.A, Yuan, Z. | | 登録日 | 2015-09-30 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Structure and Function of the Su(H)-Hairless Repressor Complex, the Major Antagonist of Notch Signaling in Drosophila melanogaster.
Plos Biol., 14, 2016
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6WQU
 | | CSL (RBPJ) bound to Notch3 RAM and DNA | | 分子名称: | DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*CP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), Neurogenic locus notch homolog protein 3, ... | | 著者 | Kovall, R.A, Gagliani, E, Hall, D. | | 登録日 | 2020-04-29 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | PIM-induced phosphorylation of Notch3 promotes breast cancer tumorigenicity in a CSL-independent fashion.
J.Biol.Chem., 296, 2021
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3MXG
 | | Structure of Shiga Toxin type 2 (Stx2) B Pentamer Mutant Q40L | | 分子名称: | D-xylose, Shiga-like toxin 2 subunit B | | 著者 | Kovall, R.A, Vander Wielen, B.D, Friedmann, D.R, Flagler, M.J. | | 登録日 | 2010-05-07 | | 公開日 | 2011-01-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Molecular basis of differential B-pentamer stability of Shiga toxins 1 and 2.
Plos One, 5, 2010
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1AVQ
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1TTU
 | | Crystal Structure of CSL bound to DNA | | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3', 5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3', ... | | 著者 | Kovall, R.A, Hendrickson, W.A. | | 登録日 | 2004-06-23 | | 公開日 | 2004-08-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA
Embo J., 23, 2004
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1I6S
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8EML
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2FO1
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4E37
 | | Crystal Structure of P. aeruginosa catalase, KatA tetramer | | 分子名称: | Catalase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | VanderWielen, B.D, Wilson, J.J, Kovall, R.A. | | 登録日 | 2012-03-09 | | 公開日 | 2013-03-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | KatA, the Major Catalase in Pseudomonas aeruginosa, Assists in Protecting Anaerobic Bacteria From Metabolic and Exogenous Nitric Oxide
To be Published
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7RTI
 | | X-ray structure of RBPJ-L3MBTL3(dT62)-DNA complex | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*CP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), ... | | 著者 | Hall, D.P, Kovall, R.A, Yuan, Z. | | 登録日 | 2021-08-13 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The structure, binding and function of a Notch transcription complex involving RBPJ and the epigenetic reader protein L3MBTL3.
Nucleic Acids Res., 50, 2022
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7RTE
 | | X-ray structure of wild type RBPJ-L3MBTL3-DNA complex | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*CP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), ... | | 著者 | Hall, D.P, Kovall, R.A, Yuan, Z. | | 登録日 | 2021-08-13 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | The structure, binding and function of a Notch transcription complex involving RBPJ and the epigenetic reader protein L3MBTL3.
Nucleic Acids Res., 50, 2022
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3IAG
 | | CSL (RBP-Jk) bound to HES-1 nonconsensus site | | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*AP*CP*AP*CP*GP*AP*T)-3', 5'-D(*TP*TP*AP*TP*CP*GP*TP*GP*TP*GP*AP*AP*AP*GP*A)-3', ... | | 著者 | Friedmann, D.R, Kovall, R.A. | | 登録日 | 2009-07-13 | | 公開日 | 2009-11-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Thermodynamic and structural insights into CSL-DNA complexes.
Protein Sci., 19, 2010
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3BRD
 | | CSL (Lag-1) bound to DNA with Lin-12 RAM peptide, P212121 | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*DAP*DAP*DTP*DCP*DTP*DTP*DTP*DCP*DCP*DCP*DAP*DCP*DAP*DGP*DT)-3'), DNA (5'-D(*DTP*DTP*DAP*DCP*DTP*DGP*DTP*DGP*DGP*DGP*DAP*DAP*DAP*DGP*DA)-3'), ... | | 著者 | Wilson, J.J, Kovall, R.A. | | 登録日 | 2007-12-21 | | 公開日 | 2008-04-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex.
J.Biol.Chem., 283, 2008
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3BRG
 | | CSL (RBP-Jk) bound to DNA | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*DAP*DAP*DTP*DCP*DTP*DTP*DTP*DCP*DCP*DCP*DAP*DCP*DAP*DGP*DT)-3'), DNA (5'-D(*DTP*DTP*DAP*DCP*DTP*DGP*DTP*DGP*DGP*DGP*DAP*DAP*DAP*DGP*DA)-3'), ... | | 著者 | Friedmann, D.R, Kovall, R.A. | | 登録日 | 2007-12-21 | | 公開日 | 2008-04-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex.
J.Biol.Chem., 283, 2008
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3BRF
 | | CSL (Lag-1) bound to DNA with Lin-12 RAM peptide, C2221 | | 分子名称: | DNA (5'-D(*DAP*DAP*DTP*DCP*DTP*DTP*DTP*DCP*DCP*DCP*DAP*DCP*DAP*DGP*DT)-3'), DNA (5'-D(*DTP*DTP*DAP*DCP*DTP*DGP*DTP*DGP*DGP*DGP*DAP*DAP*DAP*DGP*DA)-3'), Lin-12 and glp-1 phenotype protein 1, ... | | 著者 | Wilson, J.J, Kovall, R.A. | | 登録日 | 2007-12-21 | | 公開日 | 2008-04-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex.
J.Biol.Chem., 283, 2008
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4J2X
 | | CSL (RBP-Jk) with corepressor KyoT2 bound to DNA | | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3', 5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3', ... | | 著者 | Collins, K.J, Kovall, R.A. | | 登録日 | 2013-02-05 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structure and Function of the CSL-KyoT2 Corepressor Complex: A Negative Regulator of Notch Signaling.
Structure, 22, 2014
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1R5L
 | | Crystal Structure of Human Alpha-Tocopherol Transfer Protein Bound to its Ligand | | 分子名称: | (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL, PROTEIN (Alpha-tocopherol transfer protein) | | 著者 | Min, K.C, Kovall, R.A, Hendrickson, W.A. | | 登録日 | 2003-10-10 | | 公開日 | 2003-11-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of human alpha-tocopherol transfer protein bound to its ligand: Implications for ataxia with vitamin E deficiency
Proc.Natl.Acad.Sci.USA, 100, 2003
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5EG6
 | | CSL-RITA complex bound to DNA | | 分子名称: | 1,2-ETHANEDIOL, 1,4-BUTANEDIOL, DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3'), ... | | 著者 | Tabaja, N.H, Kovall, R.A. | | 登録日 | 2015-10-26 | | 公開日 | 2017-04-26 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.094 Å) | | 主引用文献 | CSL-RITA complex bound to DNA
To Be Published
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