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PDB: 33 件

1JMW
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Propagating Conformational Changes Over Long (And Short) Distances
分子名称: methyl-accepting chemotaxis protein II
著者Koshland Jr, D.E, Yu, E.W.
登録日2001-07-20
公開日2001-08-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Propagating conformational changes over long (and short) distances in proteins.
Proc.Natl.Acad.Sci.USA, 98, 2001
9ICD
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BU of 9icd by Molmil
CATALYTIC MECHANISM OF NADP+-DEPENDENT ISOCITRATE DEHYDROGENASE: IMPLICATIONS FROM THE STRUCTURES OF MAGNESIUM-ISOCITRATE AND NADP+ COMPLEXES
分子名称: ISOCITRATE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hurley, J.H, Dean, A.M, Koshland Jr, D.E, Stroud, R.M.
登録日1991-07-29
公開日1991-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Catalytic mechanism of NADP(+)-dependent isocitrate dehydrogenase: implications from the structures of magnesium-isocitrate and NADP+ complexes.
Biochemistry, 30, 1991
2AGG
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BU of 2agg by Molmil
succinyl-AAPK-trypsin acyl-enzyme at 1.28 A resolution
分子名称: CALCIUM ION, Cationic trypsin, SULFATE ION, ...
著者Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E.
登録日2005-07-26
公開日2006-05-16
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Proc.Natl.Acad.Sci.USA, 103, 2006
2AGE
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BU of 2age by Molmil
Succinyl-AAPR-trypsin acyl-enzyme at 1.15 A resolution
分子名称: CALCIUM ION, Cationic trypsin, succinyl-Ala-Ala-Pro-Arg
著者Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E.
登録日2005-07-26
公開日2006-05-16
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Proc.Natl.Acad.Sci.USA, 103, 2006
2AGI
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BU of 2agi by Molmil
The leupeptin-trypsin covalent complex at 1.14 A resolution
分子名称: CALCIUM ION, SULFATE ION, beta-trypsin, ...
著者Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E.
登録日2005-07-26
公開日2006-05-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Proc.Natl.Acad.Sci.USA, 103, 2006
2AH4
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BU of 2ah4 by Molmil
guanidinobenzoyl-trypsin acyl-enzyme at 1.13 A resolution
分子名称: 4-carbamimidamidobenzoic acid, CALCIUM ION, SULFATE ION, ...
著者Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E.
登録日2005-07-26
公開日2006-05-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Proc.Natl.Acad.Sci.USA, 103, 2006
1PB3
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BU of 1pb3 by Molmil
Sites of binding and orientation in a four location model for protein stereospecificity.
分子名称: GLYCEROL, Isocitrate dehydrogenase [NADP], SULFATE ION
著者Mesecar, A.D, Koshland Jr, D.E.
登録日2003-05-14
公開日2003-06-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Sites of Binding and Orientation in a Four-Location Model for Protein Stereospecificity.
IUBMB Life, 49, 2000
1PB1
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A four location model to explain the stereospecificity of proteins.
分子名称: GLYCEROL, ISOCITRIC ACID, Isocitrate dehydrogenase [NADP], ...
著者Mesecar, A.D, Koshland Jr, D.E.
登録日2003-05-14
公開日2003-06-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Biology: A New Model for Protein Stereospecificity.
Nature, 403, 2000
1OYE
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BU of 1oye by Molmil
Structural Basis of Multiple Binding Capacity of the AcrB multidrug Efflux Pump
分子名称: 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID, Acriflavine resistance protein B
著者Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E.
登録日2003-04-03
公開日2003-05-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.48 Å)
主引用文献Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump.
Science, 300, 2003
1OY9
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BU of 1oy9 by Molmil
Structural Basis of Multiple Drug Binding Capacity of the AcrB Multidrug Efflux Pump
分子名称: Acriflavine resistance protein B, ETHIDIUM
著者Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E.
登録日2003-04-03
公開日2003-05-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump.
Science, 300, 2003
1OYD
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BU of 1oyd by Molmil
Structural Basis of Multiple Binding Capacity of the AcrB multidrug Efflux Pump
分子名称: Acriflavine resistance protein B, DEQUALINIUM
著者Yu, E.W, MeDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E.
登録日2003-04-03
公開日2003-05-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump.
Science, 300, 2003
1OY8
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BU of 1oy8 by Molmil
Structural Basis of Multiple Drug Binding Capacity of the AcrB Multidrug Efflux Pump
分子名称: Acriflavine resistance protein B, RHODAMINE 6G
著者Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E.
登録日2003-04-03
公開日2003-05-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.63 Å)
主引用文献Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump.
Science, 300, 2003
1OY6
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BU of 1oy6 by Molmil
Structural Basis of the Multiple Binding Capacity of the AcrB Multidrug Efflux Pump
分子名称: Acriflavine resistance protein B
著者Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E.
登録日2003-04-03
公開日2003-05-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.68 Å)
主引用文献Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump.
Science, 300, 2003
1P8F
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BU of 1p8f by Molmil
A four location model to explain the stereospecificity of proteins.
分子名称: GLYCEROL, ISOCITRIC ACID, Isocitrate dehydrogenase [NADP], ...
著者Mesecar, A.D, Koshland Jr, D.E.
登録日2003-05-07
公開日2003-05-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural biology: A new model for protein stereospecificity.
Nature, 403, 2000
1TMG
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BU of 1tmg by Molmil
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59F mutant
分子名称: CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ...
著者Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
登録日2004-06-10
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1TM1
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BU of 1tm1 by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX OF SUBTILISIN BPN' WITH CHYMOTRYPSIN INHIBITOR 2
分子名称: CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ...
著者Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
登録日2004-06-10
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1TM3
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BU of 1tm3 by Molmil
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59k mutant
分子名称: CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ...
著者Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
登録日2004-06-10
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1TM7
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BU of 1tm7 by Molmil
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59Y mutant
分子名称: CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ...
著者Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
登録日2004-06-10
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1TM4
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BU of 1tm4 by Molmil
crystal structure of the complex of subtilsin BPN'with chymotrypsin inhibitor 2 M59G mutant
分子名称: CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ...
著者Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
登録日2004-06-10
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1TM5
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BU of 1tm5 by Molmil
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59A mutant
分子名称: CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ...
著者Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
登録日2004-06-10
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1TO1
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BU of 1to1 by Molmil
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 Y61A mutant
分子名称: CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ...
著者Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
登録日2004-06-11
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1TO2
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BU of 1to2 by Molmil
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59K, in pH 9 cryosoak
分子名称: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ...
著者Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
登録日2004-06-11
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1LW6
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BU of 1lw6 by Molmil
Crystal Structure of the Complex of Subtilisin BPN' with Chymotrypsin Inhibitor 2 at 1.5 Angstrom Resolution
分子名称: CALCIUM ION, SUBTILISIN BPN', SUBTILISIN-CHYMOTRYPSIN INHIBITOR-2A, ...
著者Radisky, E.S, Koshland JR, D.E.
登録日2002-05-30
公開日2002-08-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A clogged gutter mechanism for protease inhibitors.
Proc.Natl.Acad.Sci.USA, 99, 2002
1Y34
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BU of 1y34 by Molmil
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 E60A mutant
分子名称: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ...
著者Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E.
登録日2004-11-23
公開日2005-05-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
Biochemistry, 44, 2005
1Y4A
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BU of 1y4a by Molmil
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59R/E60S mutant
分子名称: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ...
著者Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E.
登録日2004-11-30
公開日2005-05-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
Biochemistry, 44, 2005

 

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