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PDB: 17 件
6MWN
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Crystal structure of hepatitis A virus IRES domain V in complex with Fab HAVx
分子名称: Fab HAVx Heavy Chain, Fab HAVx Light Chain, HAV dV RNA (92-MER)
著者Koirala, D, Shao, Y, Piccirilli, J.A.
登録日2018-10-29
公開日2019-08-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.838 Å)
主引用文献A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites.
Nat Commun, 10, 2019
6U8K
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Crystal structure of hepatitis C virus IRES junction IIIabc in complex with Fab HCV3
分子名称: Heavy chain of Fab HCV3, JIIIabc RNA (68-MER), Light chain of Fab HCV3
著者Koirala, D, Lewicka, A, Koldobskaya, Y, Huang, H, Piccirilli, J.A.
登録日2019-09-05
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Synthetic Antibody Binding to a Preorganized RNA Domain of Hepatitis C Virus Internal Ribosome Entry Site Inhibits Translation.
Acs Chem.Biol., 15, 2020
6U8D
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Crystal structure of hepatitis C virus IRES junction IIIabc in complex with Fab HCV2
分子名称: Heavy chain of Fab HCV2, JIIIabc RNA (68-MER), Light chain of Fab HCV2
著者Koirala, D, Lewicka, A, Koldobskaya, Y, Huang, H, Piccirilli, J.A.
登録日2019-09-04
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.807 Å)
主引用文献Synthetic Antibody Binding to a Preorganized RNA Domain of Hepatitis C Virus Internal Ribosome Entry Site Inhibits Translation.
Acs Chem.Biol., 15, 2020
6XJQ
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Crystal structure of a self-alkylating ribozyme - alkylated form with biotinylated epoxide substrate
分子名称: 2-{[(4R)-4-hydroxyhexyl]oxy}ethyl 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate, Fab HAVx Heavy Chain, Fab HAVx Light Chain, ...
著者Koirala, D, Piccirilli, J.A.
登録日2020-06-24
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.708 Å)
主引用文献Structural basis for substrate binding and catalysis by a self-alkylating ribozyme.
Nat.Chem.Biol., 18, 2022
6XJW
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Crystal structure of a self-alkylating ribozyme - alkylated form without biotin moiety
分子名称: 2-{[(4R)-4-hydroxyhexyl]oxy}ethyl pentanoate, Fab HAVx Heavy Chain, Fab HAVx Light Chain, ...
著者Koirala, D, Piccirilli, J.A.
登録日2020-06-24
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.918 Å)
主引用文献Structural basis for substrate binding and catalysis by a self-alkylating ribozyme.
Nat.Chem.Biol., 18, 2022
6XJY
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Crystal structure of a self-alkylating ribozyme - short time incubation with the epoxide substrate
分子名称: Fab HAVx Heavy Chain, Fab HAVx Light Chain, Self-alkylating ribozyme (58-MER)
著者Koirala, D, Piccirilli, J.A.
登録日2020-06-24
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.156 Å)
主引用文献Structural basis for substrate binding and catalysis by a self-alkylating ribozyme.
Nat.Chem.Biol., 18, 2022
6XJZ
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BU of 6xjz by Molmil
Crystal structure of a self-alkylating ribozyme - apo form
分子名称: Fab HAVx Heavy Chain, Fab HAVx Light Chain, Self-alkylating ribozyme (58-MER)
著者Koirala, D, Piccirilli, J.A.
登録日2020-06-24
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.488 Å)
主引用文献Structural basis for substrate binding and catalysis by a self-alkylating ribozyme.
Nat.Chem.Biol., 18, 2022
8DP3
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Crystal structure of coxsackievirus B3 cloverleaf RNA replication element
分子名称: Fab BL3-6 Heavy Chain, Fab BL3-6 Light Chain, PHOSPHATE ION, ...
著者Das, N.K, Koirala, D.
登録日2022-07-14
公開日2023-04-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Crystal structure of a highly conserved enteroviral 5' cloverleaf RNA replication element.
Nat Commun, 14, 2023
8VM9
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The crystal structure of rhinovirus B14 RNA replication element sD-loop mutant in complex with Fab BL3-6
分子名称: Heavy Chain of Fab BL3-6, Light Chain of Fab BL3-6, RNA (85-MER)
著者Das, N.K, Koirala, D.
登録日2024-01-13
公開日2024-07-24
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for a highly conserved RNA-mediated enteroviral genome replication.
Nucleic Acids Res., 2024
8VM8
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The crystal structure of coxsackievirus B3 RNA replication element sD-loop mutant in complex with Fab BL3-6
分子名称: Heavy Chain of Fab BL3-6, Light Chain of Fab BL3-6, RNA (93-MER)
著者Das, N.K, Koirala, D.
登録日2024-01-13
公開日2024-07-24
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structural basis for a highly conserved RNA-mediated enteroviral genome replication.
Nucleic Acids Res., 2024
8VMA
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The crystal structure of rhinovirus C15 RNA replication element sD-loop mutant in complex with Fab BL3-6
分子名称: Heavy Chain of Fab BL3-6, Light Chain of Fab BL3-6, RNA (88-MER)
著者Das, N.K, Koirala, D.
登録日2024-01-13
公開日2024-07-24
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structural basis for a highly conserved RNA-mediated enteroviral genome replication.
Nucleic Acids Res., 2024
8VMB
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The crystal structure of rhinovirus C15 RNA replication element sB-loop mutant in complex with Fab BL3-6
分子名称: Heavy Chain of Fab BL3-6, Light Chain of Fab BL3-6, RNA (83-MER)
著者Das, N.K, Koirala, D.
登録日2024-01-13
公開日2024-07-24
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Structural basis for a highly conserved RNA-mediated enteroviral genome replication.
Nucleic Acids Res., 2024
8T2B
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BU of 8t2b by Molmil
Crystal structure of SCV PTE G18C mutant RNA in complex with Fab BL3-6
分子名称: BL3-6 Fab heavy chain, BL3-6 Fab light chain, RNA (90-MER)
著者Ojha, M, Koirala, D.
登録日2023-06-05
公開日2024-01-10
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Structure of saguaro cactus virus 3' translational enhancer mimics 5' cap for eIF4E binding.
Proc.Natl.Acad.Sci.USA, 121, 2024
8T2A
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Crystal structure of SCV PTE G18A mutant RNA in complex with Fab BL3-6
分子名称: BL3-6 Fab heavy chain, BL3-6 Fab light chain, RNA (90-MER)
著者Ojha, M, Koirala, D.
登録日2023-06-05
公開日2024-01-10
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Structure of saguaro cactus virus 3' translational enhancer mimics 5' cap for eIF4E binding.
Proc.Natl.Acad.Sci.USA, 121, 2024
8T2O
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Crystal structure of SCV PTE G18U RNA in complex with Fab BL3-6
分子名称: BL3-6 Fab heavy chain, BL3-6 Fab light chain, RNA (90-MER)
著者Ojha, M, Koirala, D.
登録日2023-06-06
公開日2024-01-10
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献Structure of saguaro cactus virus 3' translational enhancer mimics 5' cap for eIF4E binding.
Proc.Natl.Acad.Sci.USA, 121, 2024
8T29
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BU of 8t29 by Molmil
Crystal structure of SCV PTE RNA in complex with Fab BL3-6
分子名称: BL3-6 Fab heavy chain, BL3-6 Fab light chain, RNA (90-MER)
著者Ojha, M, Koirala, D.
登録日2023-06-05
公開日2024-01-10
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献Structure of saguaro cactus virus 3' translational enhancer mimics 5' cap for eIF4E binding.
Proc.Natl.Acad.Sci.USA, 121, 2024
6B3K
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Crystal structure of mutant Spinach RNA aptamer in complex with Fab BL3-6
分子名称: Heavy chain of Fab BL3-6, Light chain of Fab BL3-6, MAGNESIUM ION, ...
著者DasGupta, S, Koirala, D, Shelke, S.A, Piccirilli, J.A.
登録日2017-09-22
公開日2017-12-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography.
Nucleic Acids Res., 46, 2018

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件を2024-08-28に公開中

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