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PDB: 276 件

2NZW
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Crystal Structure of alpha1,3-Fucosyltransferase
分子名称: Alpha1,3-fucosyltransferase, SULFATE ION
著者Sun, H.Y, Ko, T.P.
登録日2006-11-27
公開日2007-01-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design.
J. Biol. Chem., 282, 2007
2NZX
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Crystal Structure of alpha1,3-Fucosyltransferase with GDP
分子名称: Alpha1,3-fucosyltransferase, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION
著者Sun, H.Y, Ko, T.P.
登録日2006-11-27
公開日2007-01-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design.
J. Biol. Chem., 282, 2007
2NZY
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Crystal Structure of alpha1,3-Fucosyltransferase with GDP-fucose
分子名称: Alpha1,3-Fucosyltransferase, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, ...
著者Sun, H.Y, Ko, T.P.
登録日2006-11-27
公開日2007-01-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design.
J. Biol. Chem., 282, 2007
2AFX
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Crystal structure of human glutaminyl cyclase in complex with 1-benzylimidazole
分子名称: 1-BENZYL-1H-IMIDAZOLE, Glutaminyl-peptide cyclotransferase, SULFATE ION, ...
著者Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J.
登録日2005-07-26
公開日2005-08-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation
Proc.Natl.Acad.Sci.Usa, 102, 2005
2AFM
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Crystal structure of human glutaminyl cyclase at pH 6.5
分子名称: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
著者Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J.
登録日2005-07-26
公開日2005-08-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation
Proc.Natl.Acad.Sci.Usa, 102, 2005
2AFS
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Crystal structure of the genetic mutant R54W of human glutaminyl cyclase
分子名称: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
著者Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J.
登録日2005-07-26
公開日2005-08-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation
Proc.Natl.Acad.Sci.Usa, 102, 2005
2AFZ
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Crystal structure of human glutaminyl cyclase in complex with 1-vinylimidazole
分子名称: 1-VINYLIMIDAZOLE, Glutaminyl-peptide cyclotransferase, SULFATE ION, ...
著者Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J.
登録日2005-07-26
公開日2005-08-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation
Proc.Natl.Acad.Sci.Usa, 102, 2005
2AFU
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Crystal structure of human glutaminyl cyclase in complex with glutamine t-butyl ester
分子名称: Glutaminyl-peptide cyclotransferase, TERT-BUTYL D-ALPHA-GLUTAMINATE, ZINC ION
著者Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J.
登録日2005-07-26
公開日2005-08-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation
Proc.Natl.Acad.Sci.Usa, 102, 2005
2AZJ
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Crystal structure for the mutant D81C of Sulfolobus solfataricus hexaprenyl pyrophosphate synthase
分子名称: Geranylgeranyl pyrophosphate synthetase
著者Sun, H.Y, Ko, T.P, Kuo, C.J, Guo, R.T, Chou, C.C, Liang, P.H, Wang, A.H.J.
登録日2005-09-11
公開日2006-03-14
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures
J.Bacteriol., 187, 2005
2AZK
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Crystal structure for the mutant W136E of Sulfolobus solfataricus hexaprenyl pyrophosphate synthase
分子名称: Geranylgeranyl pyrophosphate synthetase
著者Sun, H.Y, Ko, T.P, Kuo, C.J, Guo, R.T, Chou, C.C, Liang, P.H, Wang, A.H.J.
登録日2005-09-12
公開日2006-03-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures
J.Bacteriol., 187, 2005
2AZL
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Crystal structure for the mutant F117E of Thermotoga maritima octaprenyl pyrophosphate synthase
分子名称: octoprenyl-diphosphate synthase
著者Sun, H.Y, Ko, T.P, Kuo, C.J, Guo, R.T, Chou, C.C, Liang, P.H, Wang, A.H.
登録日2005-09-12
公開日2006-03-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures
J.Bacteriol., 187, 2005
2AFO
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Crystal structure of human glutaminyl cyclase at pH 8.0
分子名称: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
著者Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J.
登録日2005-07-26
公開日2005-08-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation
Proc.Natl.Acad.Sci.Usa, 102, 2005
2AFW
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Crystal structure of human glutaminyl cyclase in complex with N-acetylhistamine
分子名称: Glutaminyl-peptide cyclotransferase, N-[2-(1H-IMIDAZOL-4-YL)ETHYL]ACETAMIDE, SULFATE ION, ...
著者Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J.
登録日2005-07-26
公開日2005-08-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation
Proc.Natl.Acad.Sci.Usa, 102, 2005
1VG6
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Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima F132A/L128A/I123A mutant
分子名称: octoprenyl-diphosphate synthase
著者Guo, R.T, Kuo, C.J, Ko, T.P, Chou, C.C, Liang, P.H, Wang, A.H.-J.
登録日2004-04-23
公開日2004-05-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products
Biochemistry, 43, 2004
1VG2
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Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima A76Y mutant
分子名称: octoprenyl-diphosphate synthase
著者Guo, R.T, Kuo, C.J, Ko, T.P, Chou, C.C, Liang, P.H, Wang, A.H.-J.
登録日2004-04-23
公開日2004-05-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products
Biochemistry, 43, 2004
1VG7
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Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima F132A/L128A/I123A/D62A mutant
分子名称: octoprenyl-diphosphate synthase
著者Guo, R.T, Kuo, C.J, Ko, T.P, Chou, C.C, Liang, P.H, Wang, A.H.-J.
登録日2004-04-23
公開日2004-05-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products
Biochemistry, 43, 2004
1VG3
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Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima A76Y/S77F mutant
分子名称: SULFATE ION, octoprenyl-diphosphate synthase
著者Guo, R.T, Kuo, C.J, Ko, T.P, Chou, C.C, Liang, P.H, Wang, A.H.-J.
登録日2004-04-23
公開日2004-05-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products
Biochemistry, 43, 2004
1VG4
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Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima F132A/L128A mutant
分子名称: octoprenyl-diphosphate synthase
著者Guo, R.T, Kuo, C.J, Ko, T.P, Chou, C.C, Liang, P.H, Wang, A.H.-J.
登録日2004-04-23
公開日2004-05-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products
Biochemistry, 43, 2004
3PHL
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The apo-form UDP-glucose 6-dehydrogenase
分子名称: UDP-glucose 6-dehydrogenase
著者Chen, Y.Y, Ko, T.P, Lin, C.H, Chen, W.H, Wang, A.H.J.
登録日2010-11-04
公開日2011-09-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
J.Struct.Biol., 175, 2011
2DFL
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Crystal structure of left-handed RadA filament
分子名称: DNA repair and recombination protein radA
著者Chen, L.T, Ko, T.P, Wang, T.F, Wang, A.H.J.
登録日2006-03-02
公開日2007-01-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the left-handed archaeal RadA helical filament: identification of a functional motif for controlling quaternary structures and enzymatic functions of RecA family proteins
Nucleic Acids Res., 35, 2007
2DTN
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Crystal structure of Helicobacter pylori undecaprenyl pyrophosphate synthase complexed with pyrophosphate
分子名称: DIPHOSPHATE, undecaprenyl pyrophosphate synthase
著者Guo, R.T, Kuo, C.J, Chen, C.L, Ko, T.P, Liang, P.H, Wang, A.H.-J.
登録日2006-07-13
公開日2007-06-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Biochemical characterization, crystal structure, and inhibitors of Helicobacter pylori undecaprenyl pyrophosphate synthase
To be Published
2E99
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E. coli undecaprenyl pyrophosphate synthase in complex with BPH-608
分子名称: (1-HYDROXY-1-PHOSPHONO-2-[1,1';3',1'']TERPHENYL-3-YL-ETHYL)-PHOSPHONIC ACID, Undecaprenyl pyrophosphate synthetase
著者Guo, R.T, Ko, T.P, Cao, R, Liang, P.H, Oldfield, E, Wang, A.H.J.
登録日2007-01-24
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E8X
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S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and GPP
分子名称: GERANYL DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION
著者Guo, R.T, Ko, T.P, Chen, C.K.-M, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J.
登録日2007-01-24
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E93
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S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with BPH-629
分子名称: Geranylgeranyl pyrophosphate synthetase, [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID
著者Guo, R.T, Cao, R, Ko, T.P, Chen, C.K.-M, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J.
登録日2007-01-24
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E8T
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S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium, FsPP and IPP
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, ...
著者Guo, R.T, Ko, T.P, Chen, C.K.-M, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J.
登録日2007-01-23
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007

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