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PDB: 68 件

7KKL
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SARS-CoV-2 Spike in complex with neutralizing nanobody mNb6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Schoof, M.S, Faust, B.F, Saunders, R.A, Sangwan, S, Rezelj, V, Hoppe, N, Boone, M, Billesboelle, C.B, Puchades, C, Azumaya, C.M, Kratochvil, H.T, Zimanyi, M, Desphande, I, Liang, J, Dickinson, S, Nguyen, H.C, Chio, C.M, Merz, G.E, Thompson, M.C, Diwanji, D, Schaefer, K, Anand, A.A, Dobzinski, N, Zha, B.S, Simoneau, C.R, Leon, K, White, K.M, Chio, U.S, Gupta, M, Jin, M, Li, F, Liu, Y, Zhang, K, Bulkley, D, Sun, M, Smith, A.M, Rizo, A.N, Moss, F, Brilot, A.F, Pourmal, S, Trenker, R, Pospiech, T, Gupta, S, Barsi-Rhyne, B, Belyy, V, Barile-Hill, A.W, Nock, S, Liu, Y, Krogan, N.J, Ralston, C.Y, Swaney, D.L, Garcia-Sastre, A, Ott, M, Vignuzzi, M, Walter, P, Manglik, A, QCRG Structural Biology Consortium
登録日2020-10-27
公開日2020-11-11
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 370, 2020
2GSX
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Complement Receptor Type 2
分子名称: Complement receptor type 2
著者Gilbert, H.E, Asokan, R, Holers, V.M, Perkins, S.J.
登録日2006-04-27
公開日2006-09-26
最終更新日2024-02-14
実験手法SOLUTION SCATTERING
主引用文献The 15 SCR Flexible Extracellular Domains of Human Complement Receptor Type 2 can Mediate Multiple Ligand and Antigen Interactions.
J.Mol.Biol., 362, 2006
3CHN
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BU of 3chn by Molmil
Solution structure of human secretory IgA1
分子名称: Ig alpha-1 chain C region, Immunoglobulin kappa light chain, Secretory component
著者Bonner, A, Almogren, A, Furtado, P.B, Kerr, M.A, Perkins, S.J.
登録日2008-03-10
公開日2008-12-30
最終更新日2024-02-21
実験手法SOLUTION SCATTERING
主引用文献Location of secretory component on the Fc edge of dimeric IgA1 reveals insight into the role of secretory IgA1 in mucosal immunity.
Mucosal Immunol, 2, 2009
1TVE
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BU of 1tve by Molmil
Homoserine Dehydrogenase in complex with 4-(4-hydroxy-3-isopropylphenylthio)-2-isopropylphenol
分子名称: 4-(4-HYDROXY-3-ISOPROPYLPHENYLTHIO)-2-ISOPROPYLPHENOL, Homoserine dehydrogenase
著者Ejim, L, Mirza, I.A, Capone, C, Nazi, I, Jenkins, S, Chee, G.L, Berghuis, A.M, Wright, G.D.
登録日2004-06-29
公開日2004-07-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献New phenolic inhibitors of yeast homoserine dehydrogenase
Bioorg.Med.Chem., 12, 2004
1HAQ
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BU of 1haq by Molmil
FOUR MODELS OF HUMAN FACTOR H DETERMINED BY SOLUTION SCATTERING CURVE-FITTING AND HOMOLOGY MODELLING
分子名称: COMPLEMENT FACTOR H
著者Aslam, M, Perkins, S.J.
登録日2001-04-06
公開日2002-04-05
最終更新日2024-05-08
実験手法SOLUTION SCATTERING
主引用文献Folded-Back Solution Structure of Monomeric Factor H of Human Complement by Synchrotron X-Ray and Neutron Scattering, Analytical Ultracentrifugation and Constrained Molecular Modelling.
J.Mol.Biol., 309, 2001
2O6F
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Structure of metal- free rTp34 from Treponema pallidum
分子名称: 1,2-ETHANEDIOL, 34 kDa membrane antigen, CHLORIDE ION, ...
著者Machius, M, Brautigam, C.A, Deka, R.K, Tomchick, D.R, Lumpkins, S.B, Norgard, M.V.
登録日2006-12-07
公開日2006-12-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin.
J.Biol.Chem., 282, 2007
2O6D
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Structure of native rTp34 from Treponema pallidum
分子名称: 1,2-ETHANEDIOL, 34 kDa membrane antigen, CHLORIDE ION, ...
著者Machius, M, Brautigam, C.A, Deka, R.K, Tomchick, D.R, Lumpkins, S.B, Norgard, M.V.
登録日2006-12-07
公開日2006-12-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin.
J.Biol.Chem., 282, 2007
1W2R
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BU of 1w2r by Molmil
Solution structure of CR2 SCR 1-2 by X-ray scattering
分子名称: COMPLEMENT RECEPTOR TYPE 2 PRECURSOR,
著者Gilbert, H.E, Hannan, J.P, Holers, V.M, Perkins, S.J.
登録日2004-07-08
公開日2005-09-29
最終更新日2024-05-08
実験手法SOLUTION SCATTERING
主引用文献Solution Structure of the Complex between Cr2 Scr 1-2 and C3D of Human Complement: An X-Ray Scattering and Sedimentation Modelling Study.
J.Mol.Biol., 346, 2005
1W2S
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Solution structure of CR2 SCR 1-2 in its complex with C3d by X-ray scattering
分子名称: COMPLEMENT C3 PRECURSOR, COMPLEMENT RECEPTOR TYPE 2 PRECURSOR,
著者Gilbert, H.E, Hannan, J.P, Holers, V.M, Perkins, S.J.
登録日2004-07-08
公開日2005-09-29
最終更新日2024-05-08
実験手法SOLUTION SCATTERING
主引用文献Solution Structure of the Complex between Cr2 Scr 1-2 and C3D of Human Complement: An X-Ray Scattering and Sedimentation Modelling Study.
J.Mol.Biol., 346, 2005
2ATY
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BU of 2aty by Molmil
Complement receptor chimaeric conjugate CR2-Ig
分子名称: Complement receptor chimeric conjugate CR2-Ig
著者Gilbert, H.E, Aslam, M, Guthridge, J.M, Holers, V.M, Perkins, S.J.
登録日2005-08-26
公開日2006-01-31
最終更新日2024-02-14
実験手法SOLUTION SCATTERING
主引用文献Extended Flexible Linker Structures in the Complement Chimaeric Conjugate CR2-Ig by Scattering, Analytical Ultracentrifugation and Constrained Modelling: Implications for Function and Therapy.
J.Mol.Biol., 356, 2006
2QFG
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Solution Structure of the N-terminal SCR-1/5 fragment of Complement Factor H.
分子名称: Complement factor H
著者Okemefuna, A.I, Gilbert, H.E, Griggs, K.M, Ormsby, R.J, Gordon, D.L, Perkins, S.J.
登録日2007-06-27
公開日2007-09-25
最終更新日2024-02-21
実験手法SOLUTION SCATTERING
主引用文献The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties.
J.Mol.Biol., 375, 2008
2PIS
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BU of 2pis by Molmil
Efforts toward Expansion of the Genetic Alphabet: Structure and Replication of Unnatural Base Pairs
分子名称: DNA (5'-D(*CP*GP*(CBR)P*GP*AP*AP*(FFD)P*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
著者Matsuda, S, Fillo, J.D, Henry, A.A, Wilkins, S.J, Rai, P, Dwyer, T.J, Geierstanger, B.H, Wemmer, D.E, Schultz, P.G, Spraggon, G, Romesberg, F.E.
登録日2007-04-13
公開日2007-10-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs.
J.Am.Chem.Soc., 129, 2007
7KKK
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BU of 7kkk by Molmil
SARS-CoV-2 Spike in complex with neutralizing nanobody Nb6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Schoof, M.S, Faust, B.F, Saunders, R.A, Sangwan, S, Rezelj, V, Hoppe, N, Boone, M, Billesboelle, C.B, Puchades, C, Azumaya, C.M, Kratochvil, H.T, Zimanyi, M, Desphande, I, Liang, J, Dickinson, S, Nguyen, H.C, Chio, C.M, Merz, G.E, Thompson, M.C, Diwanji, D, Schaefer, K, Anand, A.A, Dobzinski, N, Zha, B.S, Simoneau, C.R, Leon, K, White, K.M, Chio, U.S, Gupta, M, Jin, M, Li, F, Liu, Y, Zhang, K, Bulkley, D, Sun, M, Smith, A.M, Rizo, A.N, Moss, F, Brilot, A.F, Pourmal, S, Trenker, R, Pospiech, T, Gupta, S, Barsi-Rhyne, B, Belyy, V, Barile-Hill, A.W, Nock, S, Liu, Y, Krogan, N.J, Ralston, C.Y, Swaney, D.L, Garcia-Sastre, A, Ott, M, Vignuzzi, M, Walter, P, Manglik, A, QCRG Structural Biology Consortium
登録日2020-10-27
公開日2020-11-11
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 370, 2020
2O6C
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BU of 2o6c by Molmil
Structure of selenomethionyl rTp34 from Treponema pallidum
分子名称: 1,2-ETHANEDIOL, 34 kDa membrane antigen, CHLORIDE ION, ...
著者Machius, M, Brautigam, C.A, Deka, R.K, Tomchick, D.R, Lumpkins, S.B, Norgard, M.V.
登録日2006-12-07
公開日2006-12-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin.
J.Biol.Chem., 282, 2007
2O6E
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BU of 2o6e by Molmil
Structure of native rTp34 from Treponema pallidum from zinc-soaked crystals
分子名称: 1,2-ETHANEDIOL, 34 kDa membrane antigen, CHLORIDE ION, ...
著者Machius, M, Brautigam, C.A, Deka, R.K, Tomchick, D.R, Lumpkins, S.B, Norgard, M.V.
登録日2006-12-07
公開日2006-12-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin.
J.Biol.Chem., 282, 2007
2QFH
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Solution Structure of the C-terminal SCR-16/20 fragment of Complement Factor H.
分子名称: Complement factor H
著者Okemefuna, A.I, Gilbert, H.E, Griggs, K.M, Ormsby, R.J, Gordon, D.L, Perkins, S.J.
登録日2007-06-27
公開日2007-09-25
最終更新日2024-02-21
実験手法SOLUTION SCATTERING
主引用文献The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties.
J.Mol.Biol., 375, 2008
1ZLG
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Solution structure of the extracellular matrix protein anosmin-1
分子名称: Anosmin 1
著者Hu, Y, Sun, Z, Eaton, J.T, Bouloux, P.M, Perkins, S.J.
登録日2005-05-06
公開日2006-05-09
最終更新日2024-05-22
実験手法SOLUTION SCATTERING
主引用文献Extended and Flexible Domain Solution Structure of the Extracellular Matrix Protein Anosmin-1 by X-ray Scattering, Analytical Ultracentrifugation and Constrained Modelling.
J.Mol.Biol., 350, 2005
2IC4
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BU of 2ic4 by Molmil
Solution structure of the His402 allotype of the Factor H SCR6-SCR7-SCR8 fragment
分子名称: Complement factor H
著者Fernando, A.N, Furtado, P.B, Gilbert, H.E, Clark, S.J, Day, A.J, Sim, R.B, Perkins, S.J.
登録日2006-09-12
公開日2007-04-10
最終更新日2024-02-21
実験手法SOLUTION SCATTERING
主引用文献Associative and Structural Properties of the Region of Complement Factor H Encompassing the Tyr402His Disease-related Polymorphism and its Interactions with Heparin.
J.Mol.Biol., 368, 2007
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