1TVE
Homoserine Dehydrogenase in complex with 4-(4-hydroxy-3-isopropylphenylthio)-2-isopropylphenol
Summary for 1TVE
Entry DOI | 10.2210/pdb1tve/pdb |
Related | 1EBF 1EBU 1Q7G |
Descriptor | Homoserine dehydrogenase, 4-(4-HYDROXY-3-ISOPROPYLPHENYLTHIO)-2-ISOPROPYLPHENOL (2 entities in total) |
Functional Keywords | antifungal; small molecule screening; amino acid biosynthesis, oxidoreductase |
Biological source | Saccharomyces cerevisiae (baker's yeast) |
Total number of polymer chains | 2 |
Total formula weight | 77432.39 |
Authors | Ejim, L.,Mirza, I.A.,Capone, C.,Nazi, I.,Jenkins, S.,Chee, G.L.,Berghuis, A.M.,Wright, G.D. (deposition date: 2004-06-29, release date: 2004-07-13, Last modification date: 2023-08-23) |
Primary citation | Ejim, L.,Mirza, I.A.,Capone, C.,Nazi, I.,Jenkins, S.,Chee, G.L.,Berghuis, A.M.,Wright, G.D. New phenolic inhibitors of yeast homoserine dehydrogenase Bioorg.Med.Chem., 12:3825-3830, 2004 Cited by PubMed: 15210149DOI: 10.1016/j.bmc.2004.05.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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