4XW0
 
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4XW1
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8QMH
 | | Crystal structure of RNA G2C4 repeats in complex with small synthetic molecule ANP77 | | 分子名称: | 3-(7-azanyl-1,8-naphthyridin-2-yl)-2-[(7-azanyl-1,8-naphthyridin-2-yl)methyl]-~{N}-(3-azanylpropyl)propanamide, CHLORIDE ION, RNA (5'-R(*GP*GP*CP*CP*CP*C)-3') | | 著者 | Kiliszek, A, Ryczek, M, Blaszczyk, L. | | 登録日 | 2023-09-22 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Antisense RNA C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms a triplex-like structure and binds small synthetic ligand.
Nucleic Acids Res., 2024
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5MWI
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3GM7
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6QIS
 | | Crystal structure of CAG repeats with synthetic CMBL3a compound (model II) | | 分子名称: | CMBL3a, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3'), SULFATE ION | | 著者 | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Nakatani, K. | | 登録日 | 2019-01-21 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats.
Nucleic Acids Res., 47, 2019
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6QIV
 | | Crystal structure of seleno-derivative CAG repeats with synthetic CMBL4 compound | | 分子名称: | CMBL4, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3') | | 著者 | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Nakatani, K. | | 登録日 | 2019-01-21 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats.
Nucleic Acids Res., 47, 2019
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6QIQ
 | | Crystal structure of seleno-derivative CAG repeats with synthetic CMBL3a compound | | 分子名称: | CMBL3a, RNA (5'-R(*GP*CP*AP*G)-D(P*(CSL))-R(P*AP*GP*C)-3') | | 著者 | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Micura, R, Nakatani, K. | | 登録日 | 2019-01-21 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.519 Å) | | 主引用文献 | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats.
Nucleic Acids Res., 47, 2019
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6QIT
 | | Crystal structure of CAG repeats with synthetic CMBL3b compound | | 分子名称: | CMBL3a, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3') | | 著者 | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Nakatani, K. | | 登録日 | 2019-01-21 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | | 主引用文献 | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats.
Nucleic Acids Res., 47, 2019
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6QIR
 | | Crystal structure of CAG repeats with synthetic CMBL3a compound (model I) | | 分子名称: | CMBL3a, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3') | | 著者 | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Nakatani, K. | | 登録日 | 2019-01-21 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.531 Å) | | 主引用文献 | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats.
Nucleic Acids Res., 47, 2019
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3GLP
 | | 1.23 A resolution X-ray structure of (GCUGCUGC)2 | | 分子名称: | 5'-R(*GP*CP*UP*GP*CP*UP*GP*C)-3', GLYCEROL, SULFATE ION | | 著者 | Kiliszek, A, Kierzek, R, Krzyzosiak, W.J, Rypniewski, W. | | 登録日 | 2009-03-12 | | 公開日 | 2009-05-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | | 主引用文献 | Structural insights into CUG repeats containing the 'stretched U-U wobble': implications for myotonic dystrophy.
Nucleic Acids Res., 37, 2009
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3NJ7
 | | 1.9 A resolution X-ray structure of (GGCAGCAGCC)2 | | 分子名称: | 5'-R(*GP*GP*CP*AP*GP*CP*AP*GP*CP*C)-3', SULFATE ION | | 著者 | Kiliszek, A, Kierzek, R, Krzyzosiak, W.J, Rypniewski, W. | | 登録日 | 2010-06-17 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | | 主引用文献 | Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseases.
Nucleic Acids Res., 38, 2010
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3NJ6
 | | 0.95 A resolution X-ray structure of (GGCAGCAGCC)2 | | 分子名称: | 5'-R(*GP*GP*CP*AP*GP*CP*AP*GP*CP*C)-3', SULFATE ION | | 著者 | Kiliszek, A, Kierzek, R, Krzyzosiak, W.J, Rypniewski, W. | | 登録日 | 2010-06-17 | | 公開日 | 2010-08-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseases.
Nucleic Acids Res., 38, 2010
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4E58
 | | Crystal structure of GCC(LCG)CCGC duplex containing LNA residue | | 分子名称: | RNA duplex containing CCG repeats, SULFATE ION | | 著者 | Kiliszek, A, Kierzek, R, Krzyzosiak, W.J, Rypniewski, R. | | 登録日 | 2012-03-14 | | 公開日 | 2012-12-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | | 主引用文献 | Crystallographic characterization of CCG repeats.
Nucleic Acids Res., 40, 2012
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4E59
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5EME
 | | Complex of RNA r(GCAGCAGC) with antisense PNA p(CTGCTGC) | | 分子名称: | Antisense PNA strand, CHLORIDE ION, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3') | | 著者 | Kiliszek, A, Banaszak, K, Dauter, Z, Rypniewski, W. | | 登録日 | 2015-11-06 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches-toward anti-sense therapy against TREDs.
Nucleic Acids Res., 44, 2016
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5EMG
 | | Crystal structures of PNA p(GCTGCTGC)2 duplex containing T-T mismatches | | 分子名称: | CHLORIDE ION, GPN-CPN-TPN-GPN-CPN-TPN-GPN-CPN, SODIUM ION | | 著者 | Kiliszek, A, Banaszak, K, Dauter, Z, Rypniewski, W. | | 登録日 | 2015-11-06 | | 公開日 | 2016-01-13 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | | 主引用文献 | The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches-toward anti-sense therapy against TREDs.
Nucleic Acids Res., 44, 2016
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5EMF
 | | Crystal structure of RNA r(GCUGCUGC) with antisense PNA p(GCAGCAGC) | | 分子名称: | CHLORIDE ION, RNA (5'-R(*GP*CP*UP*GP*CP*UP*GP*C)-3'), antisense PNA p(GCAGCAGC) | | 著者 | Kiliszek, A, Banaszak, K, Dauter, Z, Rypniewski, W. | | 登録日 | 2015-11-06 | | 公開日 | 2016-01-13 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | | 主引用文献 | The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches-toward anti-sense therapy against TREDs.
Nucleic Acids Res., 44, 2016
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3R1C
 | | Crystal structure of GCGGCGGC duplex | | 分子名称: | RNA (5'-R(*GP*CP*GP*GP*CP*GP*GP*C)-3'), SULFATE ION | | 著者 | Kiliszek, A, Kierzek, R, Krzyzosiak, W.J, Rypniewski, W. | | 登録日 | 2011-03-10 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.0531 Å) | | 主引用文献 | Crystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndrome.
Nucleic Acids Res., 39, 2011
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3R1D
 | | Crystal structure of GC(8BrG)GCGGCGGC duplex | | 分子名称: | BROMIDE ION, RNA (5'-R(*GP*CP*(GRB)P*GP*CP*GP*GP*CP*GP*GP*C)-3'), SULFATE ION | | 著者 | Kiliszek, A, Kierzek, R, Krzyzosiak, W.J, Rypniewski, W. | | 登録日 | 2011-03-10 | | 公開日 | 2011-06-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndrome.
Nucleic Acids Res., 39, 2011
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3R1E
 | | Crystal structure of GC(8BrG)GCGGC duplex | | 分子名称: | BROMIDE ION, CALCIUM ION, GLYCEROL, ... | | 著者 | Kiliszek, A, Kierzek, R, Krzyzosiak, W.J, Rypniewski, W. | | 登録日 | 2011-03-10 | | 公開日 | 2011-06-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (0.972 Å) | | 主引用文献 | Crystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndrome.
Nucleic Acids Res., 39, 2011
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6HNB
 | | Crystal structure of aminotransferase Aro8 from Candida albicans | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Aromatic amino acid aminotransferase I, CHLORIDE ION, ... | | 著者 | Kiliszek, A, Rzad, K, Rypniewski, W, Milewski, S, Gabriel, I. | | 登録日 | 2018-09-14 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties.
J.Struct.Biol., 205, 2019
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6HND
 | | Crystal structure of the aromatic aminotransferase Aro9 from C. Albicans | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Aromatic-amino-acid:2-oxoglutarate transaminase, POTASSIUM ION, ... | | 著者 | Kiliszek, A, Rzad, K, Rypniewski, W, Milewski, S, Gabriel, I. | | 登録日 | 2018-09-14 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties.
J.Struct.Biol., 205, 2019
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6HNV
 | | Crystal structure of aminotransferase Aro9 from C. Albicans with ligands | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINOHEXANEDIOIC ACID, 2-OXOADIPIC ACID, ... | | 著者 | Kiliszek, A, Rzad, K, Rypniewski, W, Milewski, S, Gabriel, I. | | 登録日 | 2018-09-17 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties.
J.Struct.Biol., 205, 2019
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6HNU
 | | Crystal structure of the aminotransferase Aro8 from C. Albicans with ligands | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Aromatic amino acid aminotransferase I, ... | | 著者 | Kiliszek, A, Rzad, K, Rypniewski, W, Milewski, S, Gabriel, I. | | 登録日 | 2018-09-17 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties.
J.Struct.Biol., 205, 2019
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