1TG6
 
 | | Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP | | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, GLYCEROL, ... | | Authors: | Kang, S.G, Maurizi, M.R, Thompson, M, Mueser, T, Ahvazi, B. | | Deposit date: | 2004-05-28 | | Release date: | 2005-03-22 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP
J.Struct.Biol., 148, 2004
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5X3T
 | | VapBC from Mycobacterium tuberculosis | | Descriptor: | Antitoxin VapB26, MAGNESIUM ION, Ribonuclease VapC26 | | Authors: | Kang, S.M, Kim, D.H, Yoon, H.J, Lee, B.J. | | Deposit date: | 2017-02-07 | | Release date: | 2017-06-07 | | Last modified: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Functional details of the Mycobacterium tuberculosis VapBC26 toxin-antitoxin system based on a structural study: insights into unique binding and antibiotic peptides.
Nucleic Acids Res., 45, 2017
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2BCN
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5YRZ
 | | Toxin-Antitoxin complex from Streptococcus pneumoniae | | Descriptor: | GLYCEROL, HicA, HicB, ... | | Authors: | Kang, S.M, Kim, D.H. | | Deposit date: | 2017-11-11 | | Release date: | 2018-05-23 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.304 Å) | | Cite: | Functional insights into the Streptococcus pneumoniae HicBA toxin-antitoxin system based on a structural study.
Nucleic Acids Res., 46, 2018
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1ZHC
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2B0Z
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2B12
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2B11
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2B10
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3TCX
 | | Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation | | Descriptor: | Integrin alpha-L, Intercellular adhesion molecule 1, MAGNESIUM ION | | Authors: | Kang, S, Kim, C.U, Gu, X, Owens, R.M, van Rijn, S.J, Boonyaleepun, V, Mao, Y, Springer, T.A, Jin, M.M. | | Deposit date: | 2011-08-09 | | Release date: | 2011-08-31 | | Last modified: | 2014-11-12 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity L Integrin I Domain of Native C-Terminal Helix Conformation
To be Published
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2IP6
 | | Crystal structure of PedB | | Descriptor: | PapB, SULFATE ION | | Authors: | Kang, S.O, Kim, I.K, Kim, M.K, Kim, J.H, Yim, H.S, Cha, S.S. | | Deposit date: | 2006-10-12 | | Release date: | 2007-10-02 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | High resolution crystal structure of PedB: a structural basis for the classification of pediocin-like immunity proteins
Bmc Struct.Biol., 7, 2007
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8D4W
 | | Asymmetric ene-reduction of alpha,beta-unsaturated compounds using MSMEG_2850 | | Descriptor: | Cell entry (Mce) related family protein, DI(HYDROXYETHYL)ETHER, GLYCEROL | | Authors: | Kang, S.W, Frkic, R.L, Jackson, C. | | Deposit date: | 2022-06-02 | | Release date: | 2023-01-25 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Asymmetric Ene-Reduction of alpha , beta-Unsaturated Compounds by F 420 -Dependent Oxidoreductases A Enzymes from Mycobacterium smegmatis .
Biochemistry, 62, 2023
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7CZO
 | | N-terminal domain of HipA toxin | | Descriptor: | CHLORIDE ION, Uncharacterized protein HI_0666 | | Authors: | Kang, S.M. | | Deposit date: | 2020-09-09 | | Release date: | 2021-09-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The Haemophilus influenzae HipBA toxin-antitoxin system adopts an unusual three-com-ponent regulatory mechanism
Iucrj, 9, 2022
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6A4W
 | | AcrR from Mycobacterium tuberculosis | | Descriptor: | GLYCEROL, SODIUM ION, SULFATE ION, ... | | Authors: | Kang, S.M, Kim, D.H. | | Deposit date: | 2018-06-21 | | Release date: | 2019-06-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.587 Å) | | Cite: | The crystal structure of AcrR from Mycobacterium tuberculosis reveals a one-component transcriptional regulation mechanism.
Febs Open Bio, 9, 2019
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7BY3
 | | Toxin-antitoxin complex from klebsiella pneumoniae | | Descriptor: | CopG family transcriptional regulator, Ribonuclease VapC, SULFATE ION | | Authors: | Kang, S.M. | | Deposit date: | 2020-04-21 | | Release date: | 2021-04-28 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Toxin-antitoxin complex from klebsiella pneumoniae
To Be Published
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7BYE
 | | Toxin-antitoxin complex from klebsiella pneumoniae | | Descriptor: | Antitoxin MazE, PHOSPHATE ION, Uncharacterized protein | | Authors: | Kang, S.M. | | Deposit date: | 2020-04-22 | | Release date: | 2021-04-28 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Toxin-antitoxin complex from klebsiella pneumoniae
To Be Published
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7BY2
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6A4L
 | | AcrR from Mycobacterium tuberculosis | | Descriptor: | SODIUM ION, SULFATE ION, TetR family transcriptional regulator | | Authors: | Kang, S.M. | | Deposit date: | 2018-06-20 | | Release date: | 2019-06-26 | | Last modified: | 2020-04-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The crystal structure of AcrR from Mycobacterium tuberculosis reveals a one-component transcriptional regulation mechanism.
Febs Open Bio, 9, 2019
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6AF4
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7BXY
 | | mRNA interferase from Bacillus cereus | | Descriptor: | mRNA interferase | | Authors: | Kang, S.M. | | Deposit date: | 2020-04-21 | | Release date: | 2021-04-28 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | mRNA interferase from Bacillus cereus
To Be Published
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6AF3
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7C04
 | | Crystal structure of human Trap1 with DN203492 | | Descriptor: | 4-chloranyl-1-[[2-methoxy-4-(trifluoromethyl)phenyl]methyl]pyrazolo[3,4-d]pyrimidin-6-amine, Heat shock protein 75 kDa, mitochondrial | | Authors: | Kim, D, Kim, D, Kim, S.Y, Lee, J.H, Kang, B.H, Kang, S, Lee, C. | | Deposit date: | 2020-04-30 | | Release date: | 2020-07-08 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models.
Bioorg.Chem., 101, 2020
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7C05
 | | Crystal structure of human Trap1 with DN203495 | | Descriptor: | 1-[(4-bromanyl-2-fluoranyl-phenyl)methyl]-4-chloranyl-pyrazolo[3,4-d]pyrimidin-6-amine, Heat shock protein 75 kDa, mitochondrial | | Authors: | Kim, D, Kim, D, Kim, S.Y, Lee, J.H, Kang, B.H, Kang, S, Lee, C. | | Deposit date: | 2020-04-30 | | Release date: | 2020-07-08 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models.
Bioorg.Chem., 101, 2020
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1JTD
 | | Crystal structure of beta-lactamase inhibitor protein-II in complex with TEM-1 beta-lactamase | | Descriptor: | CALCIUM ION, TEM-1 beta-lactamase, beta-lactamase inhibitor protein II | | Authors: | Lim, D.C, Park, H.U, De Castro, L, Kang, S.G, Lee, H.S, Jensen, S, Lee, K.J, Strynadka, N.C.J. | | Deposit date: | 2001-08-20 | | Release date: | 2001-10-03 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure and kinetic analysis of beta-lactamase inhibitor protein-II in complex with TEM-1 beta-lactamase.
Nat.Struct.Biol., 8, 2001
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5Y3N
 | | Structure of TRAP1 complexed with DN401 | | Descriptor: | 1-[(6-bromanyl-1,3-benzodioxol-5-yl)methyl]-4-chloranyl-pyrazolo[3,4-d]pyrimidin-6-amine, Heat shock protein 75 kDa, mitochondrial | | Authors: | Jeong, H, Park, H.K, Kang, S, Kang, B.H, Lee, C. | | Deposit date: | 2017-07-29 | | Release date: | 2017-08-30 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors.
J. Med. Chem., 60, 2017
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