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PDB: 52 件

1L1M
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SOLUTION STRUCTURE OF A DIMER OF LAC REPRESSOR DNA-BINDING DOMAIN COMPLEXED TO ITS NATURAL OPERATOR O1
分子名称: 5'-D(*AP*AP*AP*TP*TP*GP*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*TP*C)-3', 5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*GP*AP*TP*AP*AP*CP*AP*AP*TP*TP*T)-3', Lactose operon repressor
著者Kalodimos, C.G, Bonvin, A.M.J.J, Salinas, R.K, Wechselberger, R, Boelens, R, Kaptein, R.
登録日2002-02-19
公開日2002-06-26
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Plasticity in protein-DNA recognition: lac repressor interacts with its natural operator 01 through alternative conformations of its DNA-binding domain.
EMBO J., 21, 2002
1OSL
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Solution structure of a dimeric lactose DNA-binding domain complexed to a nonspecific DNA sequence
分子名称: 5'-D(*CP*GP*AP*TP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*AP*TP*CP*G)-3', Lactose operon repressor
著者Kalodimos, C.G, Bonvin, A.M.J.J, Boelens, R, Kaptein, R.
登録日2003-03-20
公開日2004-05-04
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes.
Science, 305, 2004
6AMW
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Abl1b Regulatory Module 'Activating' conformation
分子名称: Tyrosine-protein kinase ABL1
著者Kalodimos, C.G, Rossi, P, Saleh, T.
登録日2017-08-11
公開日2017-09-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Atomic view of the energy landscape in the allosteric regulation of Abl kinase.
Nat. Struct. Mol. Biol., 24, 2017
6AMV
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Abl 1b Regulatory Module 'inhibiting state'
分子名称: Tyrosine-protein kinase ABL1
著者Kalodimos, C.G, Saleh, T, Rossi, P.
登録日2017-08-11
公開日2017-09-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Atomic view of the energy landscape in the allosteric regulation of Abl kinase.
Nat. Struct. Mol. Biol., 24, 2017
2L3Q
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Structure of the prolyl trans isomer of the Crk Protein
分子名称: Trans isomer of Crk protein
著者Kalodimos, C, Sarkar, P, Saleh, T, Tzeng, S, Birge, R.
登録日2010-09-21
公開日2010-12-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for regulation of the Crk signaling protein by a proline switch.
Nat.Chem.Biol., 7, 2011
2L3S
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Structure of the autoinhibited Crk
分子名称: Autoinhibited Crk protein
著者Kalodimos, C.G, Sarkar, P, Saleh, T, Tzeng, S.R, Birge, R.
登録日2010-09-21
公開日2010-12-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for regulation of the Crk signaling protein by a proline switch.
Nat.Chem.Biol., 7, 2011
2L3P
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Structure of the prolyl cis isomer of the Crk Protein
分子名称: Cis isomer of Crk protein
著者Kalodimos, C.G, Sarkar, P, Saleh, T, Tzeng, S.R, Birge, R.
登録日2010-09-21
公開日2010-12-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for regulation of the Crk signaling protein by a proline switch.
Nat.Chem.Biol., 7, 2011
8FTX
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FlgN-FliJ fusion complex
分子名称: Flagella biosynthesis chaperone FlgN, Flagellar FliJ protein fusion
著者Rossi, P, Kalodimos, C.G.
登録日2023-01-13
公開日2023-07-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Chaperone Recycling in Late-Stage Flagellar Assembly.
J.Mol.Biol., 435, 2023
8FTW
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FliT-FliJ fusion complex
分子名称: Flagellar FliT protein, Flagellar FliJ protein fusion
著者Rossi, P, Kalodimos, C.G.
登録日2023-01-13
公開日2023-07-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Chaperone Recycling in Late-Stage Flagellar Assembly.
J.Mol.Biol., 435, 2023
6CH2
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Crystal structure of the cytoplasmic domain of FlhA and FliT-FliD complex
分子名称: Flagellar biosynthesis protein FlhA, Flagellar hook-associated protein 2,Flagellar protein FliT, GLYCEROL
著者Xing, Q, Shi, K, Kalodimos, C.G.
登録日2018-02-21
公開日2018-05-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of chaperone-substrate complexes docked onto the export gate in a type III secretion system.
Nat Commun, 9, 2018
2VDA
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Solution structure of the SecA-signal peptide complex
分子名称: MALTOPORIN, TRANSLOCASE SUBUNIT SECA
著者Gelis, I, Bonvin, A.M.J.J, Keramisanou, D, Koukaki, M, Gouridis, G, Karamanou, S, Economou, A, Kalodimos, C.G.
登録日2007-10-01
公開日2007-11-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Signal-Sequence Recognition by the Translocase Motor Seca as Determined by NMR
Cell(Cambridge,Mass.), 131, 2007
6XR6
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Abl 1b isoform active state
分子名称: Tyrosine-protein kinase ABL1
著者Xie, T, Saleh, T, Rossi, P, Kalodimos, C.G.
登録日2020-07-11
公開日2020-10-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Conformational states dynamically populated by a kinase determine its function.
Science, 370, 2020
6XR7
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Abl isoform 1b inactive1 state
分子名称: Tyrosine-protein kinase ABL1
著者Xie, T, Saleh, T, Rossi, P, Kalodimos, C.G.
登録日2020-07-11
公開日2020-10-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Conformational states dynamically populated by a kinase determine its function.
Science, 370, 2020
6XRG
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Abl 1b isoform inactive2 state
分子名称: Tyrosine-protein kinase ABL1
著者Xie, T, Saleh, T, Rossi, P, Kalodimos, C.G.
登録日2020-07-12
公開日2020-10-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Conformational states dynamically populated by a kinase determine its function.
Science, 370, 2020
2WC2
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Nmr structure of catabolite activator protein in the unliganded state
分子名称: CATABOLITE GENE ACTIVATOR
著者Popovych, N, Tzeng, S.R, Kalodimos, C.G.
登録日2009-03-06
公開日2009-04-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Camp-Mediated Allosteric Control of the Catabolite Activator Protein.
Proc.Natl.Acad.Sci.USA, 106, 2009
6CH1
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Crystal structure of the cytoplasmic domain of FlhA in monomeric form
分子名称: 1,2-ETHANEDIOL, Flagellar biosynthesis protein FlhA
著者Xing, Q, Shi, K, Kalodimos, C.G.
登録日2018-02-21
公開日2018-05-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of chaperone-substrate complexes docked onto the export gate in a type III secretion system.
Nat Commun, 9, 2018
6CH3
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Crystal structure of the cytoplasmic domain of FlhA and FliS-FliC complex
分子名称: Flagellar biosynthesis protein FlhA, Flagellar secretion chaperone FliS,Flagellin
著者Xing, Q, Shi, K, Kalodimos, C.G.
登録日2018-02-21
公開日2018-05-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Structures of chaperone-substrate complexes docked onto the export gate in a type III secretion system.
Nat Commun, 9, 2018
4BH9
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A structural model of CAP mutant (T127L and S128I) in the apo state
分子名称: cAMP-activated global transcriptional regulator CRP
著者Tzeng, S.R, Kalodimos, C.G.
登録日2013-03-30
公開日2013-05-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Allosteric inhibition through suppression of transient conformational states.
Nat. Chem. Biol., 9, 2013
4BHP
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A structural model of CAP mutant (T127L and S128I) in cGMP-bound state
分子名称: CAMP RECEPTOR PROTEIN
著者Tzeng, S.R, Kalodimos, C.G.
登録日2013-04-04
公開日2013-05-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Allosteric Inhibition Through Suppression of Transient Conformational States.
Nat.Chem.Biol., 9, 2013
7N00
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Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 648-1025 in complex with AUG-alpha
分子名称: ALK and LTK ligand 2, ALK tyrosine kinase receptor
著者Reshetnyak, A.V, Myasnikov, A.G, Rossi, P, Miller, D.J, Kalodimos, C.G.
登録日2021-05-24
公開日2021-11-24
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (2.27 Å)
主引用文献Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
7MZY
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Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 673-986
分子名称: ACETATE ION, ALK tyrosine kinase receptor
著者Reshetnyak, A.V, Sowaileh, M, Miller, D.J, Rossi, P, Myasnikov, A.G, Kalodimos, C.G.
登録日2021-05-24
公開日2021-11-24
最終更新日2021-12-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
6D6S
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Solution structure of Trigger Factor dimer
分子名称: Trigger factor
著者Saio, T, Kawagoe, S, Ishimori, K, Kalodimos, C.G.
登録日2018-04-22
公開日2018-06-13
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Oligomerization of a molecular chaperone modulates its activity.
Elife, 7, 2018
5JTN
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The structure of chaperone SecB in complex with unstructured proPhoA binding site c
分子名称: Alkaline phosphatase, Protein-export protein SecB
著者Huang, C, Saio, T, Rossi, P, Kalodimos, C.G.
登録日2016-05-09
公開日2016-08-24
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for the antifolding activity of a molecular chaperone.
Nature, 537, 2016
5JTR
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The structure of chaperone SecB in complex with unstructured MBP binding site e
分子名称: Maltose-binding periplasmic protein, Protein-export protein SecB
著者Huang, C, Saio, T, Rossi, P, Kalodimos, C.G.
登録日2016-05-09
公開日2016-08-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for the antifolding activity of a molecular chaperone.
Nature, 537, 2016
5JTL
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The structure of chaperone SecB in complex with unstructured proPhoA
分子名称: Alkaline phosphatase, Protein-export protein SecB
著者Huang, C, Saio, T, Rossi, P, Kalodimos, C.G.
登録日2016-05-09
公開日2016-08-24
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for the antifolding activity of a molecular chaperone.
Nature, 537, 2016

 

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