Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 8 results
3P9J
DownloadVisualize
BU of 3p9j by Molmil
Aurora A kinase domain with phthalazinone pyrazole inhibitor
Descriptor: 4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenylphthalazin-1(2H)-one, Serine/threonine-protein kinase 6
Authors:Kairies, N.A, Oliveira, T, Engh, R.A.
Deposit date:2010-10-17
Release date:2011-03-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Phthalazinone pyrazoles as potent, selective, and orally bioavailable inhibitors of aurora-a kinase.
J.Med.Chem., 54, 2011
3W2C
DownloadVisualize
BU of 3w2c by Molmil
Structure of Aurora kinase A complexed to benzoimidazole-indazole inhibitor XV
Descriptor: 2-{4-[3-(1H-benzimidazol-2-yl)-1H-indazol-6-yl]-1H-pyrazol-1-yl}-N-(3-methylbutyl)acetamide, Aurora kinase A
Authors:Oliveira, T.M, Kairies, N.A, Engh, R.A.
Deposit date:2012-11-28
Release date:2014-02-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Flexibility and multiple conformations of the activation and glycine rich loops of aurora A accompanying inhibitor binding
To be Published
1YOJ
DownloadVisualize
BU of 1yoj by Molmil
Crystal structure of Src kinase domain
Descriptor: proto-oncogene tyrosine-protein kinase SRC
Authors:Breitenlechner, C.B, Kairies, N.A, Honold, K, Scheiblich, S, Koll, H, Greiter, E, Koch, S, Schaefer, W, Huber, R, Engh, R.A.
Deposit date:2005-01-27
Release date:2006-01-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures of active SRC kinase domain complexes
J.Mol.Biol., 353, 2005
1YOL
DownloadVisualize
BU of 1yol by Molmil
Crystal structure of Src kinase domain in complex with CGP77675
Descriptor: 1-{4-[4-AMINO-5-(3-METHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL]BENZYL}PIPERIDIN-4-OL, Proto-oncogene tyrosine-protein kinase Src
Authors:Breitenlechner, C.B, Kairies, N.A, Honold, K, Scheiblich, S, Koll, H, Greiter, E, Koch, S, Schaefer, W, Huber, R, Engh, R.A.
Deposit date:2005-01-27
Release date:2006-01-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of active SRC kinase domain complexes
J.Mol.Biol., 353, 2005
1YOM
DownloadVisualize
BU of 1yom by Molmil
Crystal structure of Src kinase domain in complex with Purvalanol A
Descriptor: 2-({6-[(3-CHLOROPHENYL)AMINO]-9-ISOPROPYL-9H-PURIN-2-YL}AMINO)-3-METHYLBUTAN-1-OL, Proto-oncogene tyrosine-protein kinase Src
Authors:Breitenlechner, C.B, Kairies, N.A, Honold, K, Scheiblich, S, Koll, H, Greiter, E, Koch, S, Schaefer, W, Huber, R, Engh, R.A.
Deposit date:2005-01-27
Release date:2006-01-27
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of active SRC kinase domain complexes
J.Mol.Biol., 353, 2005
3W16
DownloadVisualize
BU of 3w16 by Molmil
Structure of Aurora kinase A complexed to pyrazole-aminoquinoline inhibitor III
Descriptor: 4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenylphthalazin-1(2H)-one, Aurora kinase A
Authors:Oliveira, T.M, Kairies, N.A, Engh, R.A.
Deposit date:2012-11-07
Release date:2014-02-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Flexibility and multiple conformations of the activation and glycine rich loops of Aurora A accompanying inhibitor binding
To be Published
3W10
DownloadVisualize
BU of 3w10 by Molmil
Aurora kinase A complexed to pyrazole aminoquinoline I
Descriptor: 1-(3-methoxyphenyl)-N-(5-methyl-1H-pyrazol-3-yl)isoquinolin-3-amine, Aurora kinase A
Authors:Oliveira, T.M, Kairies, N.A, Engh, R.A.
Deposit date:2012-11-06
Release date:2014-02-05
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Flexibility and multiple conformations of the activation and glycine rich loops of Aurora A accompanying inhibitor binding
To be Published
3W18
DownloadVisualize
BU of 3w18 by Molmil
Structure of Aurora kinase A complexed to benzoimidazole-indazole inhibitor XIII
Descriptor: 2-{3-[3-(1H-benzimidazol-2-yl)-1H-indazol-6-yl]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide, Aurora kinase A
Authors:Oliveira, T.M, Kairies, N.A, Engh, R.A.
Deposit date:2012-11-09
Release date:2014-02-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Flexibility and multiple conformations of the activation and glycine rich loops of Aurora A accompanying inhibitor binding
To be Published

227561

PDB entries from 2024-11-20

PDB statisticsPDBj update infoContact PDBjnumon