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PDB: 41 件
5AXD
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Crystal structure of mouse SAHH complexed with ribavirin
分子名称: 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kusakabe, Y, Ishihara, M, Tanaka, N.
登録日2015-07-24
公開日2016-07-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of mouse SAHH complexed with ribavirin
To Be Published
5AXC
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BU of 5axc by Molmil
Crystal structure of mouse SAHH complexed with 3'-keto aristeromycin
分子名称: (2S,3R,5R)-3-(6-amino-9H-purin-9-yl)-2-hydroxy-5-(hydroxymethyl)cyclopentanone, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Kusakabe, Y, Ishihara, M, Tanaka, N.
登録日2015-07-24
公開日2016-07-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of mouse SAHH complexed with 3'-keto aristeromycin
To Be Published
5AXA
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BU of 5axa by Molmil
Crystal structure of mouse SAHH complexed with adenosine
分子名称: ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Kusakabe, Y, Ishihara, M, Tanaka, N.
登録日2015-07-24
公開日2016-07-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of mouse SAHH complexed with adenosine
To Be Published
5AXB
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Crystal structure of mouse SAHH complexed with noraristeromycin
分子名称: (1S,2R,3S,4R)-4-(6-aminopurin-9-yl)cyclopentane-1,2,3-triol, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Kusakabe, Y, Ishihara, M, Tanaka, N.
登録日2015-07-24
公開日2016-07-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of mouse SAHH complexed with noraristeromycin
To Be Published
4X8Y
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Crystal structure of human PGRMC1 cytochrome b5-like domain
分子名称: Membrane-associated progesterone receptor component 1, PROTOPORPHYRIN IX CONTAINING FE
著者Nakane, T, Yamamoto, T, Shimamura, T, Kobayashi, T, Kabe, Y, Suematsu, M.
登録日2014-12-11
公開日2016-03-23
最終更新日2020-02-05
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance
Nat Commun, 7, 2016
4WCO
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BU of 4wco by Molmil
Crystal structure of extracellular domain of human lectin-like transcript 1 (LLT1), the ligand for natural killer receptor-P1A
分子名称: ACETATE ION, C-type lectin domain family 2 member D, SULFATE ION, ...
著者Kita, S, Matsubara, H, Kasai, Y, Tamaoki, T, Okabe, Y, Fukuhara, H, Kamishikiryo, J, Ose, T, Kuroki, K, Maenaka, K.
登録日2014-09-05
公開日2015-06-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Crystal structure of extracellular domain of human lectin-like transcript 1 (LLT1), the ligand for natural killer receptor-P1A
Eur.J.Immunol., 45, 2015
5WS7
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BU of 5ws7 by Molmil
Crystal structure of human MTH1(G2K/C87A/C104S mutant) in complex with 2-oxo-dATP
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-12-05
公開日2017-01-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
6ILI
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BU of 6ili by Molmil
Crystal structure of human MTH1(G2K/D120N mutant) in complex with 8-oxo-dGTP at pH 6.5
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2018-10-18
公開日2018-11-07
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5JR8
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Disposal of Iron by a Mutant form of Siderocalin NGAL
分子名称: GLYCEROL, Neutrophil gelatinase-associated lipocalin, PHOSPHATE ION
著者Rupert, P.B, Strong, R.K, Barasch, J, Hollman, M, Deng, R, Hod, E.A, Abergel, R, Allred, B, Xu, K, Darrah, S, Tekabe, Y, Perlstein, A, Bruck, E, Stauber, J, Corbin, K, Buchen, C, Slavkovich, V, Graziano, J, Spitalnik, S, Qiu, A.
登録日2016-05-05
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Disposal of iron by a mutant form of lipocalin 2.
Nat Commun, 7, 2016
6IMF
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Crystal structure of TOXIN/ANTITOXIN complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cysteine-rich venom protein triflin, GLYCEROL, ...
著者Shioi, N, Tadokoro, T, Shioi, S, Hu, Y, Kurahara, L.H, Okabe, Y, Matsubara, H, Kita, S, Ose, T, Kuroki, K, Maenaka, K, Terada, S.
登録日2018-10-22
公開日2018-12-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the complex between venom toxin and serum inhibitor from Viperidae snake.
J. Biol. Chem., 294, 2019
5GHI
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BU of 5ghi by Molmil
Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-06-20
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.211 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHO
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BU of 5gho by Molmil
Crystal structure of human MTH1(G2K/D120A mutant) in complex with 8-oxo-dGTP
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-06-20
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.191 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHQ
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BU of 5ghq by Molmil
Crystal structure of human MTH1(G2K/D120A mutant) in complex with 2-oxo-dATP under high concentrations of 2-oxo-dATP
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-06-20
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.181 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHJ
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BU of 5ghj by Molmil
Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-06-20
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHP
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BU of 5ghp by Molmil
Crystal structure of human MTH1(G2K/D120A mutant) in complex with 2-oxo-dATP
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-06-20
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.192 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
7EF9
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Crystal structure of mouse MUTYH in complex with DNA containing AP site analogue:8-oxoG (Form II)
分子名称: Adenine DNA glycosylase, DNA (5'-D(*AP*TP*GP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*CP*CP*CP*(3DR)P*GP*TP*CP*TP*C)-3'), ...
著者Nakamura, T, Nakabeppu, Y, Yamagata, Y.
登録日2021-03-21
公開日2021-06-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer.
Nucleic Acids Res., 49, 2021
7EF8
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Crystal structure of mouse MUTYH in complex with DNA containing AP site analogue:8-oxoG (Form I)
分子名称: Adenine DNA glycosylase, DNA (5'-D(*TP*AP*GP*TP*CP*CP*CP*(3DR)P*GP*TP*CP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*CP*T)-3'), ...
著者Nakamura, T, Nakabeppu, Y, Yamagata, Y.
登録日2021-03-21
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer.
Nucleic Acids Res., 49, 2021
7EFA
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Crystal structure of the complex between the C-terminal domain of mouse MUTYH and human PCNA
分子名称: Adenine DNA glycosylase, Proliferating cell nuclear antigen
著者Nakamura, T, Nakabeppu, Y, Yamagata, Y.
登録日2021-03-21
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer.
Nucleic Acids Res., 49, 2021
5GHM
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BU of 5ghm by Molmil
Crystal structure of human MTH1(G2K/D120N mutant) in complex with 8-oxo-dGTP at pH 7.0
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-06-20
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHN
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BU of 5ghn by Molmil
Crystal structure of human MTH1(G2K/D120N mutant) in complex with 2-oxo-dATP
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-06-20
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.391 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
1IRY
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BU of 1iry by Molmil
Solution structure of the hMTH1, a nucleotide pool sanitization enzyme
分子名称: hMTH1
著者Mishima, M, Itoh, N, Sakai, Y, Kamiya, H, Nakabeppu, Y, Shirakawa, M.
登録日2001-10-25
公開日2003-12-23
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of human MTH1, a Nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphates
J.Biol.Chem., 279, 2004
1V8B
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Crystal structure of a hydrolase
分子名称: ADENOSINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, adenosylhomocysteinase
著者Tanaka, N, Nakanishi, M, Kusakabe, Y, Shiraiwa, K, Kitade, Y, Nakamura, K.T.
登録日2004-01-03
公開日2004-10-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of S-Adenosyl-l-Homocysteine Hydrolase from the Human Malaria Parasite Plasmodium falciparum
J.Mol.Biol., 343, 2004
1WDY
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BU of 1wdy by Molmil
Crystal structure of ribonuclease
分子名称: 2-5A-dependent ribonuclease, 5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5')ADENOSINE
著者Tanaka, N, Nakanishi, M, Kusakabe, Y, Goto, Y, Kitade, Y, Nakamura, K.T.
登録日2004-05-19
公開日2004-10-05
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for recognition of 2',5'-linked oligoadenylates by human ribonuclease L
Embo J., 23, 2004
1J2F
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X-ray crystal structure of IRF-3 and its functional implications
分子名称: Interferon regulatory factor 3
著者Takahasi, K, Noda, N, Horiuchi, M, Mori, M, Okabe, Y, Fukuhara, Y, Terasawa, H, Fujita, T, Inagaki, F.
登録日2003-01-04
公開日2003-11-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献X-ray crystal structure of IRF-3 and its functional implications.
Nat.Struct.Biol., 10, 2003
2DLC
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BU of 2dlc by Molmil
Crystal structure of the ternary complex of yeast tyrosyl-tRNA synthetase
分子名称: MAGNESIUM ION, O-(ADENOSINE-5'-O-YL)-N-(L-TYROSYL)PHOSPHORAMIDATE, T-RNA (76-MER), ...
著者Tsunoda, M, Kusakabe, Y, Tanaka, N, Nakamura, K.T.
登録日2006-04-18
公開日2007-06-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for recognition of cognate tRNA by tyrosyl-tRNA synthetase from three kingdoms.
Nucleic Acids Res., 35, 2007

 

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