4YAA
| YopH W354Y Yersinia enterocolitica PTPase apo form | Descriptor: | ACETATE ION, SULFATE ION, Tyrosine-protein phosphatase YopH | Authors: | Moise, G.E, Johnson, S.J, Hengge, A.C. | Deposit date: | 2015-02-17 | Release date: | 2015-10-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Conservative Tryptophan Mutants of the Protein Tyrosine Phosphatase YopH Exhibit Impaired WPD-Loop Function and Crystallize with Divanadate Esters in Their Active Sites. Biochemistry, 54, 2015
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3PSI
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4Z6B
| YopH W354H Yersinia enterocolitica PTPase in the apo form | Descriptor: | ACETATE ION, GLYCEROL, Tyrosine-protein phosphatase YopH | Authors: | Moise, G.E, Johnson, S.J, Hengge, A.C. | Deposit date: | 2015-04-04 | Release date: | 2015-10-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Conservative Tryptophan Mutants of the Protein Tyrosine Phosphatase YopH Exhibit Impaired WPD-Loop Function and Crystallize with Divanadate Esters in Their Active Sites. Biochemistry, 54, 2015
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3F9A
| W354F Yersinia enterocolitica PTPase complexed with tungstate | Descriptor: | TUNGSTATE(VI)ION, Tyrosine-protein phosphatase yopH | Authors: | Brandao, T.A.S, Robinson, H, Johnson, S.J, Hengge, A.C. | Deposit date: | 2008-11-13 | Release date: | 2009-01-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Impaired acid catalysis by mutation of a protein loop hinge residue in a YopH mutant revealed by crystal structures. J.Am.Chem.Soc., 131, 2009
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3F9B
| W354F Yersinia enterocolitica PTPase complexed with divanadate | Descriptor: | Divanadate ion, GLYCEROL, Tyrosine-protein phosphatase yopH, ... | Authors: | Brandao, T.A.S, Robinson, H, Johnson, S.J, Hengge, A.C. | Deposit date: | 2008-11-13 | Release date: | 2009-01-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Impaired acid catalysis by mutation of a protein loop hinge residue in a YopH mutant revealed by crystal structures. J.Am.Chem.Soc., 131, 2009
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3F99
| W354F Yersinia enterocolitica PTPase apo form | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase yopH | Authors: | Brandao, T.A.S, Robinson, H, Johnson, S.J, Hengge, A.C. | Deposit date: | 2008-11-13 | Release date: | 2009-01-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Impaired acid catalysis by mutation of a protein loop hinge residue in a YopH mutant revealed by crystal structures. J.Am.Chem.Soc., 131, 2009
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4H43
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4HAH
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4ITU
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3QKP
| Protein Tyrosine Phosphatase 1B - Apo W179F mutant with open WPD-loop | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Tyrosine-protein phosphatase non-receptor type 1 | Authors: | Brandao, T.A.S, Johnson, S.J, Hengge, A.C. | Deposit date: | 2011-02-01 | Release date: | 2012-08-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The molecular details of WPD-loop movement differ in the protein-tyrosine phosphatases YopH and PTP1B. Arch.Biochem.Biophys., 525, 2012
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3QKQ
| Protein Tyrosine Phosphatase 1B - W179F mutant bound with vanadate | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Tyrosine-protein phosphatase non-receptor type 1, ... | Authors: | Brandao, T.A.S, Johnson, S.J, Hengge, A.C. | Deposit date: | 2011-02-01 | Release date: | 2012-08-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The molecular details of WPD-loop movement differ in the protein-tyrosine phosphatases YopH and PTP1B. Arch.Biochem.Biophys., 525, 2012
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6BB8
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6YSF
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6YSL
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6DT6
| Crystal Structure of the YopH PTP1B Chimera 3 PTPase bound to vanadate | Descriptor: | Targeted effector protein, VANADATE ION | Authors: | Morales, Y, Johnson, S.J, Hengge, A.C. | Deposit date: | 2018-06-15 | Release date: | 2018-08-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases. Biochemistry, 57, 2018
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6DRB
| Crystal Structure of the YopH PTP1B WPD loop Chimera 3 PTPase bound to tungstate | Descriptor: | TUNGSTATE(VI)ION, Targeted effector protein | Authors: | Morales, Y, Johnson, S.J, Hengge, A.C. | Deposit date: | 2018-06-11 | Release date: | 2018-08-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.745 Å) | Cite: | A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases. Biochemistry, 57, 2018
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6DR1
| YopH PTP1B Chimera 2 PTPase | Descriptor: | Targeted effector protein | Authors: | Morales, Y, Johnson, S.J, Hengge, A.C. | Deposit date: | 2018-06-11 | Release date: | 2018-08-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases. Biochemistry, 57, 2018
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6DR7
| YopH PTP1B WPD loop Chimera 2 PTPase bound to vanadate | Descriptor: | ACETATE ION, Targeted effector protein, VANADATE ION | Authors: | Moise, G, Morales, Y, Johnson, S.J, Hengge, A.C. | Deposit date: | 2018-06-11 | Release date: | 2018-08-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.849 Å) | Cite: | A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases. Biochemistry, 57, 2018
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6DR9
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5SYR
| Crystal Structure of ATPase delta1-79 Spa47 R350A | Descriptor: | Probable ATP synthase SpaL/MxiB, SULFATE ION | Authors: | Morales, Y, Johnson, S.J, Burgess, J.L, Burgess, R.A, Dickenson, N.E. | Deposit date: | 2016-08-11 | Release date: | 2016-11-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and Biochemical Characterization of Spa47 Provides Mechanistic Insight into Type III Secretion System ATPase Activation and Shigella Virulence Regulation. J. Biol. Chem., 291, 2016
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5SYP
| Crystal Structure of ATPase delta1-79 Spa47 K165A | Descriptor: | Probable ATP synthase SpaL/MxiB, SULFATE ION | Authors: | Morales, Y, Johnson, S.J, Burgess, J.L, Burgess, R.A, Dickenson, N.E. | Deposit date: | 2016-08-11 | Release date: | 2016-11-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural and Biochemical Characterization of Spa47 Provides Mechanistic Insight into Type III Secretion System ATPase Activation and Shigella Virulence Regulation. J. Biol. Chem., 291, 2016
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5SWJ
| Crystal Structure of ATPase delta1-79 Spa47 | Descriptor: | Probable ATP synthase SpaL/MxiB, SULFATE ION | Authors: | Morales, Y, Johnson, S.J, Burgess, J.L, Burgess, R.A, Dickenson, N.E. | Deposit date: | 2016-08-08 | Release date: | 2016-11-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Structural and Biochemical Characterization of Spa47 Provides Mechanistic Insight into Type III Secretion System ATPase Activation and Shigella Virulence Regulation. J. Biol. Chem., 291, 2016
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5SWL
| Crystal Structure of ATPase delta1-79 Spa47 E188A | Descriptor: | Probable ATP synthase SpaL/MxiB, SULFATE ION | Authors: | Morales, Y, Johnson, S.J, Burgess, J.L, Burgess, R.A, Dickenson, N.E. | Deposit date: | 2016-08-08 | Release date: | 2016-11-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Biochemical Characterization of Spa47 Provides Mechanistic Insight into Type III Secretion System ATPase Activation and Shigella Virulence Regulation. J. Biol. Chem., 291, 2016
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3I7Z
| Protein Tyrosine Phosphatase 1B - Transition state analog for the first catalytic step | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, EGFR receptor fragment, GLYCEROL, ... | Authors: | Brandao, T.A.S, Johnson, S.J, Hengge, A.C. | Deposit date: | 2009-07-09 | Release date: | 2010-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Insights into the reaction of protein-tyrosine phosphatase 1B: crystal structures for transition state analogs of both catalytic steps. J.Biol.Chem., 285, 2010
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3I80
| Protein Tyrosine Phosphatase 1B - Transition state analog for the second catalytic step | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Tyrosine-protein phosphatase non-receptor type 1, ... | Authors: | Brandao, T.A.S, Johnson, S.J, Hengge, A.C. | Deposit date: | 2009-07-09 | Release date: | 2010-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Insights into the reaction of protein-tyrosine phosphatase 1B: crystal structures for transition state analogs of both catalytic steps. J.Biol.Chem., 285, 2010
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