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PDB: 66 件

6O7E
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Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with AMPPNP in type III-A CRISPR-Cas system
分子名称: Csm1, Csm2, Csm3, ...
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
6O7I
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BU of 6o7i by Molmil
Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system
分子名称: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm2, Csm3, ...
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
6O6X
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BU of 6o6x by Molmil
Crystal structure of Csm6 W14A/E337A mutant in complex with cA4 by cocrystallization
分子名称: Csm6, Cyclic RNA cA4
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity.
Mol.Cell, 75, 2019
6O6S
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BU of 6o6s by Molmil
Crystal structure of Apo Csm6
分子名称: Csm6
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity.
Mol.Cell, 75, 2019
6O7H
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BU of 6o7h by Molmil
Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system
分子名称: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm2, Csm3, ...
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
6O74
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Crystal structure of Csm1-Csm4 cassette in complex with AMPPNP
分子名称: Csm1, Csm4, MANGANESE (II) ION, ...
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
6O7D
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BU of 6o7d by Molmil
Crystal structure of Csm1-Csm4 cassette in complex with one ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm4, ...
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
6OV0
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Crystal structure of Csm6 in complex with A4>p by soaking A4>p into Csm6
分子名称: RNA (5'-R(*AP*AP*AP*(A23))-3'), Uncharacterized protein
著者Jia, N, Patel, D.J.
登録日2019-05-06
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity.
Mol.Cell, 75, 2019
6PPR
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BU of 6ppr by Molmil
Cryo-EM structure of AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP and DNA
分子名称: ATP-dependent DNA helicase (UvrD/REP), DNA (70-MER), IRON/SULFUR CLUSTER, ...
著者Jia, N, Unciuleac, M, Shuman, S, Patel, D.J.
登録日2019-07-08
公開日2019-11-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection.
Proc.Natl.Acad.Sci.USA, 116, 2019
6PPJ
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BU of 6ppj by Molmil
Cryo-EM structure of AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP
分子名称: ATP-dependent DNA helicase (UvrD/REP), IRON/SULFUR CLUSTER, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Jia, N, Unciuleac, M, Shuman, S, Patel, D.J.
登録日2019-07-07
公開日2019-11-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection.
Proc.Natl.Acad.Sci.USA, 116, 2019
6PPU
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BU of 6ppu by Molmil
Cryo-EM structure of AdnAB-AMPPNP-DNA complex
分子名称: ATP-dependent DNA helicase (UvrD/REP), DNA (29-MER), IRON/SULFUR CLUSTER, ...
著者Jia, N, Unciuleac, M, Shuman, S, Patel, D.J.
登録日2019-07-08
公開日2019-11-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection.
Proc.Natl.Acad.Sci.USA, 116, 2019
5Y6K
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BU of 5y6k by Molmil
Human serum trnasferrin bound to a fluorescent probe
分子名称: (2S)-6-[2-(7-azido-4-methyl-2-oxidanylidene-chromen-3-yl)ethanoylamino]-2-[bis(2-hydroxy-2-oxoethyl)amino]hexanoic acid, FE (III) ION, MALONATE ION, ...
著者Jiang, N, Cheng, T, Wang, M, Chan, G.C.F, Jin, L, Li, H, Sun, H.
登録日2017-08-12
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Tracking iron-associated proteomes in pathogens by a fluorescence approach.
Metallomics, 10, 2018
8K34
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BU of 8k34 by Molmil
Cryo-EM structure of SPARTA gRNA binary complex
分子名称: MAGNESIUM ION, Piwi domain-containing protein, RNA (5'-R(P*AP*AP*AP*CP*GP*GP*CP*UP*CP*UP*AP*AP*UP*CP*UP*AP*UP*UP*AP*GP*U)-3'), ...
著者Zhang, J.T, Jia, N.
登録日2023-07-14
公開日2024-01-17
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
8WYF
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BU of 8wyf by Molmil
Cryo-EM structure of DSR2-DSAD1-NAD+ (partial) complex
分子名称: Bacillus phage SPbeta DSAD1 protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2 family protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WYC
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BU of 8wyc by Molmil
Cryo-EM structure of DSR2 (H171A)-tube-NAD+ (partial) complex
分子名称: Bacillus phage SPR Tube protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WYE
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BU of 8wye by Molmil
Cryo-EM structure of DSR2-DSAD1 (partial) complex
分子名称: Bacillus phage SPbeta DSAD1 protein, SIR2 family protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.49 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WYB
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BU of 8wyb by Molmil
Cryo-EM structure of DSR2 (H171A)-tube-NAD+ complex
分子名称: Bacillus phage SPR Tube protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WYA
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BU of 8wya by Molmil
Cryo-EM structure of DSR2-tube complex
分子名称: Bacillus phage SPbeta tube protein, SIR2 family protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WY8
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BU of 8wy8 by Molmil
Cryo-EM structure of DSR2 apo complex
分子名称: SIR2 family protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WY9
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BU of 8wy9 by Molmil
Cryo-EM structure of DSR2 apo (partial) complex
分子名称: SIR2 family protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.57 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WYD
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BU of 8wyd by Molmil
Cryo-EM structure of DSR2-DSAD1 complex
分子名称: Bacillus phage SPbeta DSAD1 protein, SIR2 family protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.56 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
4QLA
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BU of 4qla by Molmil
Crystal structure of juvenile hormone epoxide hydrolase from the silkworm Bombyx mori
分子名称: Juvenile hormone epoxide hydrolase, PENTAETHYLENE GLYCOL
著者Zhou, K, Jia, N, Hu, C, Jiang, Y.L, Yang, J.P, Chen, Y, Li, S, Zhou, C.Z.
登録日2014-06-11
公開日2014-09-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of juvenile hormone epoxide hydrolase from the silkworm Bombyx mori.
Proteins, 82, 2014
7Y85
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BU of 7y85 by Molmil
CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA in complex with TPR-CHAT protease bound to self RNA target
分子名称: CHAT domain protein, MAGNESIUM ION, RAMP superfamily protein, ...
著者Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
登録日2022-06-22
公開日2022-12-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase.
Nat Commun, 13, 2022
7Y81
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BU of 7y81 by Molmil
CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA complex bound to non-self RNA target
分子名称: MAGNESIUM ION, Non-self RNA target, RAMP superfamily protein, ...
著者Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
登録日2022-06-22
公開日2022-12-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.54 Å)
主引用文献Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase.
Nat Commun, 13, 2022
7Y80
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BU of 7y80 by Molmil
CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA binary complex
分子名称: MAGNESIUM ION, RAMP superfamily protein, ZINC ION, ...
著者Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
登録日2022-06-22
公開日2022-12-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.71 Å)
主引用文献Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase.
Nat Commun, 13, 2022

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