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PDB: 48 results

1NYS
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Crystal Structure of Activin A Bound to the ECD of ActRIIB P41
Descriptor: Inhibin beta A chain, activin receptor
Authors:Thompson, T.B, Woodruff, T.K, Jardetzky, T.S.
Deposit date:2003-02-13
Release date:2003-04-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions
EMBO J., 22, 2003
7RAM
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Cryo-EM Structure of the HCMV gHgLgO Trimer Derived from AD169 and TR strains in complex with PDGFRalpha
Descriptor: Envelope glycoprotein H, Envelope glycoprotein L, Envelope glycoprotein O, ...
Authors:Liu, J, Vanarsdall, A.L, Chen, D, Johnson, D.C, Jardetzky, T.S.
Deposit date:2021-07-02
Release date:2022-06-08
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha.
Mbio, 12, 2021
4GRG
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Crystal structure of IgE complexed with E2_79, an anti-IgE inhibitor
Descriptor: ANTI-IGE INHIBITOR E2_79, Ig epsilon chain C region
Authors:Kim, B, Jardetzky, T.S.
Deposit date:2012-08-24
Release date:2012-12-12
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (4.24 Å)
Cite:Accelerated disassembly of IgE-receptor complexes by a disruptive macromolecular inhibitor.
Nature, 491, 2012
4GIP
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Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 (PIV5) fusion protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1, Fusion glycoprotein F2
Authors:Welch, B.D, Liu, Y, Kors, C.A, Leser, G.P, Jardetzky, T.S, Lamb, R.A.
Deposit date:2012-08-08
Release date:2012-09-19
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GT7
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An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, non-receptor binding conformation
Descriptor: Ig epsilon chain C region, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Wurzburg, B.A, Kim, B.K, Jardetzky, T.S.
Deposit date:2012-08-28
Release date:2012-09-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, nonreceptor binding conformation.
J.Biol.Chem., 287, 2012
4FZH
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Structure of the Ulster Strain Newcastle Disease Virus Hemagglutinin-Neuraminidase Reveals Auto-Inhibitory Interactions Associated with Low Virulence
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-neuraminidase
Authors:Yuan, P, Paterson, R.G, Leser, G.P, Lamb, R.A, Jardetzky, T.S.
Deposit date:2012-07-06
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.5008 Å)
Cite:Structure of the ulster strain newcastle disease virus hemagglutinin-neuraminidase reveals auto-inhibitory interactions associated with low virulence.
Plos Pathog., 8, 2012
4JF7
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Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Welch, B.D, Yuan, P, Bose, S, Kors, C.A, Lamb, R.A, Jardetzky, T.S.
Deposit date:2013-02-27
Release date:2013-09-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5018 Å)
Cite:Structure of the Parainfluenza Virus 5 (PIV5) Hemagglutinin-Neuraminidase (HN) Ectodomain.
Plos Pathog., 9, 2013
7SHT
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Structure of a partially disrupted IgE high affinity receptor complex bound to an omalizumab variant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, ...
Authors:Pennington, L.F, Jardetzky, T.S.
Deposit date:2021-10-11
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (7.29 Å)
Cite:Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.
Nat Commun, 12, 2021
1F6A
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Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)ri(alpha)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ...
Authors:Garman, S.C, Wurzburg, B.A, Tarchevskaya, S.S, Kinet, J.P, Jardetzky, T.S.
Deposit date:2000-06-20
Release date:2000-07-20
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc (epsilon) RI (alpha).
Nature, 406, 2000
1FP5
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CRYSTAL STRUCTURE ANALYSIS OF THE HUMAN IGE-FC CEPSILON3-CEPSILON4 FRAGMENT.
Descriptor: IGE HEAVY CHAIN EPSILON-1
Authors:Wurzburg, B.A, Garman, S.C, Jardetzky, T.S.
Deposit date:2000-08-30
Release date:2000-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the human IgE-Fc C epsilon 3-C epsilon 4 reveals conformational flexibility in the antibody effector domains.
Immunity, 13, 2000
1F2Q
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CRYSTAL STRUCTURE OF THE HUMAN HIGH-AFFINITY IGE RECEPTOR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Garman, S.C, Kinet, J.P, Jardetzky, T.S.
Deposit date:2000-05-28
Release date:2000-06-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the human high-affinity IgE receptor.
Cell(Cambridge,Mass.), 95, 1998
1J87
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HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), HEXAGONAL CRYSTAL FORM 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ...
Authors:Garman, S.C, Sechi, S, Kinet, J.P, Jardetzky, T.S.
Deposit date:2001-05-20
Release date:2001-08-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
J.Mol.Biol., 311, 2001
1J89
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HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), TETRAGONAL CRYSTAL FORM 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ...
Authors:Garman, S.C, Sechi, S, Kinet, J.P, Jardetzky, T.S.
Deposit date:2001-05-20
Release date:2001-08-29
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
J.Mol.Biol., 311, 2001
1Z4Z
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA(soaked with sialic acid, pH7.0))
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z50
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with sialic acid, pH 8.0)
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4Y
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) (pH 8.0)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1ZTM
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Structure of the Uncleaved Paramyxovirus (hPIV3) Fusion Protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein
Authors:Yin, H.S, Paterson, R.G, Wen, X, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-05-27
Release date:2005-07-19
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein
Proc.Natl.Acad.Sci.USA, 102, 2005
2B0U
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The Structure of the Follistatin:Activin Complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Follistatin, IRIDIUM (III) ION, ...
Authors:Thompson, T.B, Lerch, T.F, Cook, R.W, Woodruff, T.K, Jardetzky, T.S.
Deposit date:2005-09-14
Release date:2005-10-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding.
Dev.Cell, 9, 2005
1Z4V
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with DANA, pH 7.0)
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
2B9B
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Structure of the Parainfluenza Virus 5 F Protein in its Metastable, Pre-fusion Conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
Authors:Yin, H.-S, Wen, X, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-10-11
Release date:2006-01-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation
Nature, 439, 2006
1Z4X
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand Sialyllactose (soaked with Sialyllactose, pH8.0)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4W
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with DANA, pH8.0)
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1SVF
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PARAMYXOVIRUS SV5 FUSION PROTEIN CORE
Descriptor: CHLORIDE ION, PROTEIN (FUSION GLYCOPROTEIN)
Authors:Baker, K.A, Dutch, R.E, Lamb, R.A, Jardetzky, T.S.
Deposit date:1999-02-27
Release date:1999-03-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis for paramyxovirus-mediated membrane fusion.
Mol.Cell, 3, 1999
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