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PDB: 56 件

8EBP
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HMPV F dimer bound to RSV-199 Fab
分子名称: Fusion glycoprotein F0, RSV-199 heavy chain protein, RSV-199 light chain protein
著者Wen, X, Jardetzky, T.S.
登録日2022-08-31
公開日2023-08-16
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
8E2U
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HMPV F monomer bound to RSV-199 Fab
分子名称: Fusion glycoprotein F0, RSV-199 heavy chain, RSV-199 light chain
著者Wen, X, Jardetzky, T.S.
登録日2022-08-16
公開日2023-08-16
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
2B0U
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The Structure of the Follistatin:Activin Complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Follistatin, IRIDIUM (III) ION, ...
著者Thompson, T.B, Lerch, T.F, Cook, R.W, Woodruff, T.K, Jardetzky, T.S.
登録日2005-09-14
公開日2005-10-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding.
Dev.Cell, 9, 2005
7SHU
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IgE-Fc in complex with omalizumab variant C02
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin heavy constant epsilon, ...
著者Pennington, L.F, Jardetzky, T.J, Kleinboelting, S.
登録日2021-10-11
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.
Nat Commun, 12, 2021
5W0K
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Crystal structure of EBV gHgL/CL40/gp42 N-domain
分子名称: CL40 IgG heavy chain, CL40 IgG light chain, Envelope glycoprotein H, ...
著者Sathiyamoorthy, K, Jardetzky, T.S.
登録日2017-05-31
公開日2017-10-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3QW9
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Crystal structure of betaglycan ZP-C domain
分子名称: Transforming growth factor beta receptor type 3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Lin, S.J, Jardetzky, T.S.
登録日2011-02-27
公開日2011-04-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of betaglycan zona pellucida (ZP)-C domain provides insights into ZP-mediated protein polymerization and TGF-{beta} binding.
Proc.Natl.Acad.Sci.USA, 108, 2011
3PHF
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Crystal Structure of the Epstein-Barr virus gH and gL complex
分子名称: Envelope glycoprotein H, Envelope glycoprotein L
著者Matsuura, H, Kirschner, A.N, Jardetzky, T.S.
登録日2010-11-04
公開日2011-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.58 Å)
主引用文献Crystal structure of the Epstein-Barr virus (EBV) glycoprotein H/glycoprotein L (gH/gL) complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
4GIP
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Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 (PIV5) fusion protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1, Fusion glycoprotein F2
著者Welch, B.D, Liu, Y, Kors, C.A, Leser, G.P, Jardetzky, T.S, Lamb, R.A.
登録日2012-08-08
公開日2012-09-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein.
Proc.Natl.Acad.Sci.USA, 109, 2012
7RAM
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Cryo-EM Structure of the HCMV gHgLgO Trimer Derived from AD169 and TR strains in complex with PDGFRalpha
分子名称: Envelope glycoprotein H, Envelope glycoprotein L, Envelope glycoprotein O, ...
著者Liu, J, Vanarsdall, A.L, Chen, D, Johnson, D.C, Jardetzky, T.S.
登録日2021-07-02
公開日2022-06-08
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha.
Mbio, 12, 2021
1FP5
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CRYSTAL STRUCTURE ANALYSIS OF THE HUMAN IGE-FC CEPSILON3-CEPSILON4 FRAGMENT.
分子名称: IGE HEAVY CHAIN EPSILON-1
著者Wurzburg, B.A, Garman, S.C, Jardetzky, T.S.
登録日2000-08-30
公開日2000-09-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the human IgE-Fc C epsilon 3-C epsilon 4 reveals conformational flexibility in the antibody effector domains.
Immunity, 13, 2000
4FZH
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Structure of the Ulster Strain Newcastle Disease Virus Hemagglutinin-Neuraminidase Reveals Auto-Inhibitory Interactions Associated with Low Virulence
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-neuraminidase
著者Yuan, P, Paterson, R.G, Leser, G.P, Lamb, R.A, Jardetzky, T.S.
登録日2012-07-06
公開日2012-09-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.5008 Å)
主引用文献Structure of the ulster strain newcastle disease virus hemagglutinin-neuraminidase reveals auto-inhibitory interactions associated with low virulence.
Plos Pathog., 8, 2012
4GRG
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Crystal structure of IgE complexed with E2_79, an anti-IgE inhibitor
分子名称: ANTI-IGE INHIBITOR E2_79, Ig epsilon chain C region
著者Kim, B, Jardetzky, T.S.
登録日2012-08-24
公開日2012-12-12
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (4.24 Å)
主引用文献Accelerated disassembly of IgE-receptor complexes by a disruptive macromolecular inhibitor.
Nature, 491, 2012
4GT7
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An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, non-receptor binding conformation
分子名称: Ig epsilon chain C region, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Wurzburg, B.A, Kim, B.K, Jardetzky, T.S.
登録日2012-08-28
公開日2012-09-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, nonreceptor binding conformation.
J.Biol.Chem., 287, 2012
2B9B
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Structure of the Parainfluenza Virus 5 F Protein in its Metastable, Pre-fusion Conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
著者Yin, H.-S, Wen, X, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
登録日2005-10-11
公開日2006-01-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation
Nature, 439, 2006
3T1E
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The structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a 4-helix bundle stalk
分子名称: Hemagglutinin-neuraminidase
著者Yuan, P, Swanson, K, Leser, G.P, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
登録日2011-07-21
公開日2011-09-07
最終更新日2011-09-21
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalk.
Proc.Natl.Acad.Sci.USA, 108, 2011
1BXT
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STREPTOCOCCAL SUPERANTIGEN (SSA) FROM STREPTOCOCCUS PYOGENES
分子名称: PROTEIN (STREPTOCOCCAL SUPERANTIGEN)
著者Sundberg, E, Jardetzky, T.
登録日1998-10-08
公開日1998-10-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis for HLA-DQ binding by the streptococcal superantigen SSA.
Nat.Struct.Biol., 6, 1999
1SVF
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PARAMYXOVIRUS SV5 FUSION PROTEIN CORE
分子名称: CHLORIDE ION, PROTEIN (FUSION GLYCOPROTEIN)
著者Baker, K.A, Dutch, R.E, Lamb, R.A, Jardetzky, T.S.
登録日1999-02-27
公開日1999-03-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis for paramyxovirus-mediated membrane fusion.
Mol.Cell, 3, 1999
7SHT
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Structure of a partially disrupted IgE high affinity receptor complex bound to an omalizumab variant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, ...
著者Pennington, L.F, Jardetzky, T.S.
登録日2021-10-11
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (7.29 Å)
主引用文献Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.
Nat Commun, 12, 2021
1J88
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HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), TETRAGONAL CRYSTAL FORM 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ...
著者Garman, S.C, Sechi, S, Kinet, J.P, Jardetzky, T.S.
登録日2001-05-20
公開日2001-08-29
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
J.Mol.Biol., 311, 2001
1Z4X
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand Sialyllactose (soaked with Sialyllactose, pH8.0)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
登録日2005-03-16
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4V
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with DANA, pH 7.0)
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
登録日2005-03-16
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4Z
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA(soaked with sialic acid, pH7.0))
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
登録日2005-03-16
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4W
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with DANA, pH8.0)
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
登録日2005-03-16
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z50
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with sialic acid, pH 8.0)
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
登録日2005-03-16
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4Y
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) (pH 8.0)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
登録日2005-03-16
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005

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