4IVG
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![BU of 4ivg by Molmil](/molmil-images/mine/4ivg) | Crystal structure of mitochondrial Hsp90 (TRAP1) NTD-Middle domain dimer with AMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Partridge, J.R, Lavery, L.A, Agard, D.A. | Deposit date: | 2013-01-22 | Release date: | 2014-01-22 | Last modified: | 2014-08-27 | Method: | X-RAY DIFFRACTION (1.749 Å) | Cite: | Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism. Mol.Cell, 53, 2014
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4EDY
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![BU of 4edy by Molmil](/molmil-images/mine/4edy) | Crystal structure of hH-PGDS with water displacing inhibitor | Descriptor: | 4-[2-(hydroxymethyl)naphthalen-1-yl]-N-[2-(morpholin-4-yl)ethyl]benzamide, DIMETHYL SULFOXIDE, GLUTATHIONE, ... | Authors: | Day, J.E, Thorarensen, A, Trujillo, J.I, Kiefer, J.R. | Deposit date: | 2012-03-27 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Investigation of the binding pocket of human hematopoietic prostaglandin (PG) D2 synthase (hH-PGDS): a tale of two waters. Bioorg.Med.Chem.Lett., 22, 2012
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2ZO0
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![BU of 2zo0 by Molmil](/molmil-images/mine/2zo0) | mouse NP95 SRA domain DNA specific complex 1 | Descriptor: | DNA (5'-D(*DGP*DTP*DCP*DAP*DGP*(5CM)P*DGP*DCP*DAP*DAP*DTP*DGP*DG)-3'), DNA (5'-D(*DTP*DCP*DCP*DAP*DTP*DGP*DCP*DGP*DCP*DTP*DGP*DAP*DC)-3'), E3 ubiquitin-protein ligase UHRF1 | Authors: | Hashimoto, H, Horton, J.R, Cheng, X. | Deposit date: | 2008-05-05 | Release date: | 2008-09-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix Nature, 455, 2008
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2ZRC
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![BU of 2zrc by Molmil](/molmil-images/mine/2zrc) | MsRecA Q196N Form IV | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, PHOSPHATE ION, ... | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-27 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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2ZRK
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![BU of 2zrk by Molmil](/molmil-images/mine/2zrk) | MsRecA Q196A dATP form IV | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Protein recA | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-27 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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4DD0
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![BU of 4dd0 by Molmil](/molmil-images/mine/4dd0) | EVAL processed HEWL, cisplatin aqueous glycerol | Descriptor: | GLYCEROL, Lysozyme C | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | Deposit date: | 2012-01-18 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012
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2ZRE
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![BU of 2zre by Molmil](/molmil-images/mine/2zre) | MsRecA Q196N ATPgS form IV | Descriptor: | GLYCEROL, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-27 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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2ZRM
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![BU of 2zrm by Molmil](/molmil-images/mine/2zrm) | MsRecA dATP form IV | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, GLYCEROL, Protein recA | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-27 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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4DLI
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![BU of 4dli by Molmil](/molmil-images/mine/4dli) | Human p38 MAP kinase in complex with RL87 | Descriptor: | Mitogen-activated protein kinase 14, N~4~-cyclopropyl-2-phenylquinazoline-4,7-diamine | Authors: | Gruetter, C, Getlik, M, Simard, J.R, Rauh, D. | Deposit date: | 2012-02-06 | Release date: | 2013-01-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Fluorophore labeled kinase detects ligands that bind within the MAPK insert of p38alpha kinase. Plos One, 7, 2012
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4A33
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![BU of 4a33 by Molmil](/molmil-images/mine/4a33) | CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A PYRAZOLE SULPHONAMIDE LIGAND | Descriptor: | 2,6-DICHLORO-4-(6-PIPERAZIN-1-YLPYRIDIN-3-YL)-N-(1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)BENZENESULFONAMIDE, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, TETRADECANOYL-COA | Authors: | Robinson, D.A, Brand, S, Cleghorn, L.A.T, McElroy, S.P, Smith, V.C, Hallyburton, I, Harrison, J.R, Norcross, N.R, Norval, S, Spinks, D, Stojanovski, L, Torrie, L.S, Frearson, J.A, Brenk, R, Fairlamb, A.H, Ferguson, M.A.J, Read, K.D, Wyatt, P.G, Gilbert, I.H. | Deposit date: | 2011-09-29 | Release date: | 2011-12-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors. J. Med. Chem., 55, 2012
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4DDB
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![BU of 4ddb by Molmil](/molmil-images/mine/4ddb) | EVAL processed HEWL, cisplatin DMSO paratone pH 6.5 | Descriptor: | Cisplatin, DIMETHYL SULFOXIDE, Lysozyme C | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | Deposit date: | 2012-01-18 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012
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4IYN
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![BU of 4iyn by Molmil](/molmil-images/mine/4iyn) | Structure of mitochondrial Hsp90 (TRAP1) with ADP-ALF4- | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, MAGNESIUM ION, ... | Authors: | Partridge, J.R, Lavery, L.A, Agard, D.A. | Deposit date: | 2013-01-28 | Release date: | 2014-01-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.312 Å) | Cite: | Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism. Mol.Cell, 53, 2014
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3BJZ
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![BU of 3bjz by Molmil](/molmil-images/mine/3bjz) | Crystal structure of Pseudomonas aeruginosa phosphoheptose isomerase | Descriptor: | CHLORIDE ION, Phosphoheptose isomerase, SULFATE ION | Authors: | Walker, J.R, Evdokimova, E, Kudritska, M, Osipiuk, J, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-12-05 | Release date: | 2007-12-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and Function of Sedoheptulose-7-phosphate Isomerase, a Critical Enzyme for Lipopolysaccharide Biosynthesis and a Target for Antibiotic Adjuvants. J.Biol.Chem., 283, 2008
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3BQO
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![BU of 3bqo by Molmil](/molmil-images/mine/3bqo) | Crystal Structure of TRF1 TRFH domain and TIN2 peptide complex | Descriptor: | TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 1 | Authors: | Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. | Deposit date: | 2007-12-20 | Release date: | 2008-02-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins. Science, 319, 2008
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3BPR
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![BU of 3bpr by Molmil](/molmil-images/mine/3bpr) | Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor C52 | Descriptor: | 2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE, CHLORIDE ION, Proto-oncogene tyrosine-protein kinase MER, ... | Authors: | Walker, J.R, Huang, X, Finerty Jr, P.J, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2007-12-19 | Release date: | 2008-01-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural insights into the inhibited states of the Mer receptor tyrosine kinase. J.Struct.Biol., 165, 2009
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4AXP
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![BU of 4axp by Molmil](/molmil-images/mine/4axp) | NMR structure of Hsp12, a protein induced by and required for dietary restriction-induced lifespan extension in yeast. | Descriptor: | 12 KDA HEAT SHOCK PROTEIN | Authors: | Herbert, A.P, Riesen, M, Bloxam, L, Kosmidou, E, Wareing, B.M, Johnson, J.R, Phelan, M.M, Pennington, S.R, Lian, L.Y, Morgan, A. | Deposit date: | 2012-06-13 | Release date: | 2012-08-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR Structure of Hsp12, a Protein Induced by and Required for Dietary Restriction-Induced Lifespan Extension in Yeast. Plos One, 7, 2012
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2ZO2
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![BU of 2zo2 by Molmil](/molmil-images/mine/2zo2) | Mouse NP95 SRA domain non-specific DNA complex | Descriptor: | DNA (5'-D(*DAP*DAP*DCP*DTP*DGP*DCP*DGP*DCP*DAP*DGP*DTP*DT)-3'), E3 ubiquitin-protein ligase UHRF1, PHOSPHATE ION | Authors: | Hashimoto, H, Horton, J.R, Cheng, X. | Deposit date: | 2008-05-05 | Release date: | 2008-09-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix Nature, 455, 2008
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2ZRI
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![BU of 2zri by Molmil](/molmil-images/mine/2zri) | MsRecA Q196A ADP form IV | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Protein recA | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-27 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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2ZRB
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![BU of 2zrb by Molmil](/molmil-images/mine/2zrb) | MsRecA Q196E Form II' | Descriptor: | PHOSPHATE ION, Protein recA | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-27 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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2ZRJ
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![BU of 2zrj by Molmil](/molmil-images/mine/2zrj) | MsRecA Q196A ATPgS form IV | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-08-27 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallogr.,Sect.D, 64, 2008
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2ZTC
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![BU of 2ztc by Molmil](/molmil-images/mine/2ztc) | MtRuvA Form II | Descriptor: | GLYCEROL, Holliday junction ATP-dependent DNA helicase ruvA | Authors: | Prabu, J.R, Thamotharan, S, Khanduja, J.S, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2008-10-01 | Release date: | 2009-05-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystallographic and modelling studies on Mycobacterium tuberculosis RuvA Additional role of RuvB-binding domain and inter species variability Biochim.Biophys.Acta, 1794, 2009
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4IMV
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![BU of 4imv by Molmil](/molmil-images/mine/4imv) | |
4EQR
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![BU of 4eqr by Molmil](/molmil-images/mine/4eqr) | Crystal structure of the Y361F mutant of Staphylococcus aureus CoADR | Descriptor: | CHLORIDE ION, COENZYME A, Coenzyme A disulfide reductase, ... | Authors: | Wallace, B.D, Edwards, J.S, Wallen, J.R, Claiborne, A, Redinbo, M.R. | Deposit date: | 2012-04-19 | Release date: | 2012-10-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Turnover-Dependent Covalent Inactivation of Staphylococcus aureus Coenzyme A-Disulfide Reductase by Coenzyme A-Mimetics: Mechanistic and Structural Insights. Biochemistry, 51, 2012
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4IGB
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![BU of 4igb by Molmil](/molmil-images/mine/4igb) | Crystal structure of the N-terminal domain of the Streptococcus gordonii adhesin Sgo0707 | Descriptor: | ACETATE ION, GLYCEROL, LPXTG cell wall surface protein, ... | Authors: | Nylander, A, Svensater, G, Senadheera, D.B, Cvitkovitch, D.G, Davies, J.R, Persson, K. | Deposit date: | 2012-12-17 | Release date: | 2013-06-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structural and Functional Analysis of the N-terminal Domain of the Streptococcus gordonii Adhesin Sgo0707 Plos One, 8, 2013
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4ELL
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![BU of 4ell by Molmil](/molmil-images/mine/4ell) | |