4DYM
 
 | | Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00135 | | Descriptor: | 1-(3-{6-[(CYCLOPROPYLMETHYL)AMINO]IMIDAZO[1,2-B]PYRIDAZIN-3-YL}PHENYL)ETHANONE, Activin receptor type-1, GLYCEROL, ... | | Authors: | Chaikuad, A, Sanvitale, C, Cooper, C, Canning, P, Mahajan, P, Daga, N, Petrie, K, Alfano, I, Gileadi, O, Fedorov, O, Krojer, T, Filippakopoulos, P, Muniz, J.R.C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) | | Deposit date: | 2012-02-29 | | Release date: | 2012-03-21 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00135
To be Published
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3TJ1
 | | Crystal Structure of RNA Polymerase I Transcription Initiation Factor Rrn3 | | Descriptor: | RNA polymerase I-specific transcription initiation factor RRN3 | | Authors: | Blattner, C, Jennebach, S, Herzog, F, Mayer, A, Cheung, A.C.M, Witte, G, Lorenzen, K, Hopfner, K.-P, Heck, A.J.R, Aebersold, R, Cramer, P. | | Deposit date: | 2011-08-23 | | Release date: | 2011-09-28 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth.
Genes Dev., 25, 2011
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3U23
 | | Atomic resolution crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide from human RIN3 | | Descriptor: | 1,2-ETHANEDIOL, CD2-associated protein, Ras and Rab interactor 3 | | Authors: | Simister, P.C, Rouka, E, Janning, M, Muniz, J.R.C, Kirsch, K.H, Knapp, S, von Delft, F, Filippakopoulos, P, Arrowsmith, C.H, Krojer, T, Edwards, A.M, Weigelt, J, Bountra, C, Feller, S.M, Structural Genomics Consortium (SGC) | | Deposit date: | 2011-09-30 | | Release date: | 2011-12-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.11 Å) | | Cite: | Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3).
J.Biol.Chem., 290, 2015
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3VMR
 | | Crystal structure of Staphylococcus aureus membrane-bound transglycosylase in complex with moenomycin | | Descriptor: | MOENOMYCIN, Monofunctional glycosyltransferase | | Authors: | Huang, C.Y, Shih, H.W, Lin, L.Y, Tien, Y.W, Cheng, T.J.R, Cheng, W.C, Wong, C.H, Ma, C. | | Deposit date: | 2011-12-15 | | Release date: | 2012-04-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.688 Å) | | Cite: | Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism
Proc.Natl.Acad.Sci.USA, 109, 2012
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3VRF
 | | The crystal structure of hemoglobin from woolly mammoth in the carbonmonoxy forms | | Descriptor: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, ... | | Authors: | Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H. | | Deposit date: | 2012-04-09 | | Release date: | 2012-11-07 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structures of haemoglobin from woolly mammoth in liganded and unliganded states.
Acta Crystallogr.,Sect.D, 68, 2012
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3VMS
 | | Crystal structure of Staphylococcus aureus membrane-bound transglycosylase in complex with NBD-Lipid II | | Descriptor: | Monofunctional glycosyltransferase | | Authors: | Huang, C.Y, Shih, H.W, Lin, L.Y, Tien, Y.W, Cheng, T.J.R, Cheng, W.C, Wong, C.H, Ma, C. | | Deposit date: | 2011-12-15 | | Release date: | 2012-04-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.202 Å) | | Cite: | Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism
Proc.Natl.Acad.Sci.USA, 109, 2012
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3VUS
 | | Escherichia coli PgaB N-terminal domain | | Descriptor: | ACETATE ION, MERCURY (II) ION, Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase, ... | | Authors: | Nishiyama, T, Noguchi, H, Yoshida, H, Park, S.-Y, Tame, J.R.H. | | Deposit date: | 2012-07-05 | | Release date: | 2012-11-14 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | The structure of the deacetylase domain of Escherichia coli PgaB, an enzyme required for biofilm formation: a circularly permuted member of the carbohydrate esterase 4 family
Acta Crystallogr.,Sect.D, 69, 2013
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3WWF
 | | Crystal structure of the computationally designed Pizza2-SR protein | | Descriptor: | pizza2sr-pb protein | | Authors: | Voet, A.R.D, Noguchi, H, Addy, C, Simoncini, D, Terada, D, Unzai, S, Park, S.Y, Zhang, K.Y.J, Tame, J.R.H. | | Deposit date: | 2014-06-17 | | Release date: | 2014-10-08 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.601 Å) | | Cite: | Computational design of a self-assembling symmetrical beta-propeller protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3WW9
 | | Crystal structure of the computationally designed Pizza6 protein | | Descriptor: | GLYCEROL, SULFATE ION, pizza6 protein | | Authors: | Voet, A.R.D, Noguchi, H, Addy, C, Simoncini, D, Terada, D, Unzai, S, Park, S.Y, Zhang, K.Y.J, Tame, J.R.H. | | Deposit date: | 2014-06-17 | | Release date: | 2014-10-08 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.33 Å) | | Cite: | Computational design of a self-assembling symmetrical beta-propeller protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3WBA
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3WBE
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3WMU
 | | The structure of an anti-cancer lectin mytilec apo-form from the mussel Mytilus galloprovincialis | | Descriptor: | GLYCEROL, Lectin | | Authors: | Terada, D, Kawai, F, Noguchi, H, Unzai, S, Park, S.-Y, Ozeki, Y, Tame, J.R.H. | | Deposit date: | 2013-11-27 | | Release date: | 2014-12-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Crystal structure of MytiLec, a galactose-binding lectin from the mussel Mytilus galloprovincialis with cytotoxicity against certain cancer cell types
Sci Rep, 6, 2016
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3WW7
 | | Crystal structure of the computationally designed Pizza2 protein | | Descriptor: | GLYCEROL, Pizza2 protein | | Authors: | Voet, A.R.D, Noguchi, H, Addy, C, Simoncini, D, Terada, D, Unzai, S, Park, S.Y, Zhang, K.Y.J, Tame, J.R.H. | | Deposit date: | 2014-06-17 | | Release date: | 2014-10-08 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.697 Å) | | Cite: | Computational design of a self-assembling symmetrical beta-propeller protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3WW8
 | | Crystal structure of the computationally designed Pizza3 protein | | Descriptor: | GLYCEROL, Pizza3 protein, SULFATE ION | | Authors: | Voet, A.R.D, Noguchi, H, Addy, C, Simoncini, D, Terada, D, Unzai, S, Park, S.Y, Zhang, K.Y.J, Tame, J.R.H. | | Deposit date: | 2014-06-17 | | Release date: | 2014-10-08 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.402 Å) | | Cite: | Computational design of a self-assembling symmetrical beta-propeller protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3ZRS
 | | X-ray crystal structure of a KirBac potassium channel highlights a mechanism of channel opening at the bundle-crossing gate. | | Descriptor: | ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10, CHLORIDE ION, POTASSIUM ION | | Authors: | Bavro, V.N, De Zorzi, R, Schmidt, M.R, Muniz, J.R.C, Zubcevic, L, Sansom, M.S.P, Venien-Bryan, C, Tucker, S.J. | | Deposit date: | 2011-06-17 | | Release date: | 2012-01-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Structure of a Kirbac Potassium Channel with an Open Bundle Crossing Indicates a Mechanism of Channel Gating
Nat.Struct.Mol.Biol., 19, 2012
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3X1W
 | | Ras-related protein Rap1B with GDP | | Descriptor: | CADMIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Noguchi, H, Ikegami, T, Akashi, S, Park, S.Y, Tame, J.R.H, Unzai, S. | | Deposit date: | 2014-12-02 | | Release date: | 2015-06-03 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | The structure and conformational switching of Rap1B
Biochem.Biophys.Res.Commun., 462, 2015
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3X1Y
 | | Ras-related protein Rap1B(L9V) with GppNHp | | Descriptor: | CADMIUM ION, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Noguchi, H, Ikegami, T, Park, S.Y, Tame, J.R.H, Unzai, S. | | Deposit date: | 2014-12-02 | | Release date: | 2015-06-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.168 Å) | | Cite: | The structure and conformational switching of Rap1B
Biochem.Biophys.Res.Commun., 462, 2015
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3X1X
 | | Ras-related protein Rap1B with GppNHp | | Descriptor: | CADMIUM ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Noguchi, H, Ikegami, T, Park, S.Y, Tame, J.R.H, Unzai, S. | | Deposit date: | 2014-12-02 | | Release date: | 2015-06-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | The structure and conformational switching of Rap1B
Biochem.Biophys.Res.Commun., 462, 2015
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3X1Z
 | | Ras-related protein Rap1B(T65A) with GppNHp | | Descriptor: | GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Noguchi, H, Ikegami, T, Park, S.Y, Tame, J.R.H, Unzai, S. | | Deposit date: | 2014-12-02 | | Release date: | 2015-06-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | The structure and conformational switching of Rap1B
Biochem.Biophys.Res.Commun., 462, 2015
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3ZW5
 | | Crystal structure of the human Glyoxalase domain-containing protein 5 | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYOXALASE DOMAIN-CONTAINING PROTEIN 5, ... | | Authors: | Muniz, J.R.C, Kiyani, W, Froese, S, Vollmar, M, von Delft, F, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Yue, W.W. | | Deposit date: | 2011-07-28 | | Release date: | 2011-08-10 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal Structure of the Human Glyoxalase Domain-Containing Protein 5
To be Published
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3VMQ
 | | Crystal structure of Staphylococcus aureus membrane-bound transglycosylase: Apoenzyme | | Descriptor: | MAGNESIUM ION, Monofunctional glycosyltransferase | | Authors: | Huang, C.Y, Shih, H.W, Lin, L.Y, Tien, Y.W, Cheng, T.J.R, Cheng, W.C, Wong, C.H, Ma, C. | | Deposit date: | 2011-12-15 | | Release date: | 2012-04-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.518 Å) | | Cite: | Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism
Proc.Natl.Acad.Sci.USA, 109, 2012
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3VMT
 | | Crystal structure of Staphylococcus aureus membrane-bound transglycosylase in complex with a Lipid II analog | | Descriptor: | MAGNESIUM ION, Monofunctional glycosyltransferase, [(2R,3R,4R,5S,6R)-4-[(2R)-1-[[(2S)-1-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxidanylidene-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethylamino]-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-propan-2-yl]oxy-3-acetamido-5-[(2S,3R,4R,5R,6R)-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-(hydroxymethyl)oxan-2-yl] [oxidanyl(3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,14,18,22,26,30,34,38,42-undecaenoxy)phosphoryl] hydrogen phosphate | | Authors: | Huang, C.Y, Shih, H.W, Lin, L.Y, Tien, Y.W, Cheng, T.J.R, Cheng, W.C, Wong, C.H, Ma, C. | | Deposit date: | 2011-12-15 | | Release date: | 2012-04-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.299 Å) | | Cite: | Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism
Proc.Natl.Acad.Sci.USA, 109, 2012
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3VRE
 | | The crystal structure of hemoglobin from woolly mammoth in the deoxy form | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H. | | Deposit date: | 2012-04-09 | | Release date: | 2012-11-07 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structures of haemoglobin from woolly mammoth in liganded and unliganded states.
Acta Crystallogr.,Sect.D, 68, 2012
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3VRG
 | | The crystal structure of hemoglobin from woolly mammoth in the met form | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H. | | Deposit date: | 2012-04-09 | | Release date: | 2012-11-07 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structures of haemoglobin from woolly mammoth in liganded and unliganded states.
Acta Crystallogr.,Sect.D, 68, 2012
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3ZTG
 | | Solution structure of the RING finger-like domain of Retinoblastoma Binding Protein-6 (RBBP6) | | Descriptor: | E3 UBIQUITIN-PROTEIN LIGASE RBBP6, ZINC ION | | Authors: | Kappo, M.A, Ab, E, Atkinson, R.A, Faro, A, Muleya, V, Mulaudzi, T, Poole, J.O, McKenzie, J.M, Pugh, D.J.R. | | Deposit date: | 2011-07-07 | | Release date: | 2011-12-07 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the Ring Finger-Like Domain of Retinoblastoma Binding Protein-6 (Rbbp6) Suggests It Functions as a U-Box
J.Biol.Chem., 287, 2012
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